Exhibit 21.1

Subsidiaries of Registrant

  1. NewQuest, Inc. - Delaware

  2. NewQuest, LLC - Texas

  3. GulfQuest, L.P. - Texas

  4. HealthSpring Employer Services, Inc. - Tennessee

  5. HealthSpring of Tennessee, Inc. - Tennessee

  6. HealthSpring Management, Inc. - Tennessee

  7. HealthSpring of Alabama, Inc. - Alabama

  8. HealthSpring of Illinois I, Inc. - Illinois

  9. HealthSpring USA, LLC - Tennessee

10. HouQuest, L.L.C. - Delaware

11. NewQuest Management of Alabama, LLC - Alabama

12. NewQuest Management of Illinois, LLC - Illinois

13. Signature Health Alliance, Inc. - Tennessee

14. Texas HealthSpring, LLC - Texas

15. TexQuest, L.L.C. - Delaware

16. Tennessee Quest, LLC - Tennessee

17. NewQuest Management of Florida, LLC - Florida

18. HealthSpring Life & Health Insurance Company, Inc. - Texas

19. HealthSpring Management of America, LLC - Delaware