8-K

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

FORM 8-K

CURRENT REPORT PURSUANT
TO SECTION 13 OR 15(D) OF THE
SECURITIES EXCHANGE ACT OF 1934

Date of report (Date of earliest event reported) November 19, 2010

Home BancShares, Inc.

(Exact name of registrant as specified in its charter)

Arkansas
(State or other jurisdiction of incorporation)

000-51904
(Commission File Number) 71-0682831
(IRS Employer Identification No.)

719 Harkrider, Suite 100, Conway, Arkansas
(Address of principal executive offices) 72032
(Zip Code)

(501) 328-4770
(Registrant’s telephone number, including area code)

Not Applicable
(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 7.01 Regulation FD Disclosure.

     On November 19, 2010, Home BancShares, Inc. issued a press release announcing that its wholly owned subsidiary Centennial Bank has acquired the banking operations of Gulf State Community Bank through a loss-sharing agreement with the Federal Deposit Insurance Corporation. Copies of the press release and related supplemental materials are attached as Exhibits 99.1 and 99.2 to this Current Report and are incorporated by reference herein.

Item 9.01 Financial Statements and Exhibits.

     (d) Exhibits

99.1	Press Release: Home BancShares and Centennial Bank Further Enhance Florida Panhandle Franchise With Strategic In-Market Acquisition.
99.2	Supplemental materials to Press Release dated November 19, 2010.

SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	Home BancShares, Inc. (Registrant)
Date: November 19, 2010	/s/ Randy Mayor
	Randy Mayor
	Chief Financial Officer

EX-99.1

Exhibit 99.1

For Immediate Release: November 19, 2010

Home BancShares and Centennial Bank Further Enhance Florida Panhandle
Franchise With Strategic In-Market Acquisition

     Conway, AR — November 19, 2010 — Centennial Bank, a wholly-owned subsidiary of Home BancShares, Inc. (NASDAQ GS: HOMB) announced today it has acquired the banking operations of Gulf State Community Bank (“Gulf State”) headquartered in Carrabelle, Florida, through loss-sharing agreements with the Federal Deposit Insurance Corporation (“FDIC”).

     Depositors of Gulf State will automatically become depositors of Centennial Bank, and their deposits will continue to be insured by the FDIC up to $250,000. Customers may access their accounts through automated teller machine transactions, checks, online banking and debit card transactions. Gulf State locations normally open on Saturday will open under regular business hours on Saturday, November 20, 2010, as branches of Centennial Bank. All remaining locations will open under regular business hours on Monday, November 22, 2010, as branches of Centennial Bank. Additionally, checks drawn on Gulf State will continue to be processed, and loan customers should continue to make their payments as usual.

     During the transition period, Gulf State customer accounts will be transitioned to Centennial Bank accounts with customers ultimately enjoying the benefits of Centennial Bank’s convenient locations, plus an extensive selection of products and services. Customers may continue banking as usual and feel confident their deposits are secure, now backed by one of the country’s strongest and safest financial institutions. Employees and vendors should continue to operate business as usual.

     “We continue to execute on our very successful acquisition strategy in Florida and are happy to report yet another strategic in-market acquisition which is additive to the Coastal Community Bank, Bayside Savings Bank and Wakulla Bank transactions in the Florida Panhandle. This core deposit franchise will further enhance our strong presence in Wakulla and Franklin counties. Gulf State has been focused on the customers and the communities it serves for four decades, and this will continue under the Centennial Bank umbrella. We look forward to serving the needs of the Franklin County communities in addition to Wakulla”, said Randy Sims, Chief Executive Officer of Home BancShares and Centennial Bank.

     “We are very excited to continue building our Panhandle franchise. The regional economy continues to grow, and the unemployment rate remains well below the Florida state average in the Panhandle area. We again anticipate a smooth and seamless transition, similar to our experiences with our previously announced FDIC-assisted acquisitions. We cordially welcome Gulf State customers to the Centennial Bank family. Our local Centennial Bank team along with management from Home BancShares has been deployed to assist in the weekend resolution process.”

Financial Highlights
(based on data as of September 30, 2010)

• The acquisition is expected to provide Centennial Bank:

• Assets of approximately $112 million,

• Loans of approximately $74 million (before loan discounts and FDIC receivables),

• Investment securities of approximately $11 million,

• Deposits of approximately $100 million.

• The FDIC provides 80% loss coverage on the covered Single Family Residential and Commercial loans

• Pro forma for completion of this transaction, including the Company’s other recent acquisitions in the Florida panhandle, Centennial Bank will have #1 deposit market share in both Franklin County and Wakulla County.

• This transaction is expected to have the following financial impact on the Company:

• Immediately accretive to net income and diluted earnings per share,

• Immediately accretive to book value per share and tangible book value per share.

     Upon completion of the acquisition, the Company will continue to remain well in excess of “well capitalized” by regulatory standards, with no additional capital required to support this transaction.

     Additional information regarding the acquisition is provided in a supplemental presentation available on the Company’s website at www.homebancshares.com, under the “Investor Relations” section.

General

     Home BancShares, Inc. is a bank holding company, headquartered in Conway, Arkansas. Our wholly-owned subsidiary Centennial Bank provides a broad range of commercial and retail banking and related financial services to businesses, real estate developers and investors, individuals and municipalities. Centennial Bank has locations in central Arkansas, north central Arkansas, southern Arkansas, the Florida Keys, southwestern Florida, central Florida and the Florida Panhandle. The Company’s common stock is traded through the NASDAQ Global Select Market under the symbol “HOMB.”

     This release contains forward-looking statements regarding the Company’s plans, expectations, goals and outlook for the future. Statements in this press release that are not historical facts should be considered forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements of this type speak only as of the date of this news release. By nature, forward-looking statements involve inherent risk and uncertainties. Various factors, including, but not limited to, economic conditions, credit quality, interest rates, loan demand and changes in the assumptions used in making the forward-looking statements, could cause actual results to differ materially from those contemplated by the forward-looking statements. Additional information on factors that might affect Home BancShares, Inc.’s financial results are included in its Annual Report on Form 10-K for the year ended December 31, 2009, and in its Quarterly Reports on Form 10-Q for the quarters ended March 31, 2010 and June 30, 2010 filed with the Securities and Exchange Commission.

FOR MORE INFORMATION CONTACT:

Randy Sims	Randy Mayor
Chief Executive Officer	Chief Financial Officer
(501) 472-9571	(501) 472-1849

EX-99.2

Exhibit 99.2

FDIC-Assisted Acquisition Gulf State Community Bank November 19, 2010 NASDAQ: HOMB www.homebancshares.com

Forward Looking Statements This presentation contains forward-looking statements that relate to expectations, beliefs, projections, future plans and strategies, anticipated events or trends and similar expressions concerning matters that are not historical facts. The forward-looking statements contained herein reflect our current views about future events and financial performance and are subject to risks, uncertainties, assumptions and changes in circumstances that may cause our actual results to differ significantly from historical results and those expressed in any forward-looking statement. Some factors that could cause actual results to differ materially from historical or expected results include: factors listed in the Company's 10-K as filed with the Securities and Exchange Commission; changes in general economic conditions, either nationally or locally in the areas in which we conduct or will conduct our business; inflation, interest rate, market and monetary fluctuations; increases in competitive pressures among financial institutions and businesses offering similar products and services; higher defaults on our loan portfolio than we expect; changes in management's estimate of the adequacy of the allowance for loan losses; legislative or regulatory changes or changes in accounting principles, policies or guidelines; management's estimates and projections of interest rates and interest rate policy; the execution of our business plan; and other factors affecting the financial services industry generally or the banking industry in particular. We do not intend and disclaim any duty or obligation to update or revise any industry information or forward-looking statements set forth in this presentation to reflect new information, future events or otherwise.

Transaction Overview Purchased and assumed select assets and liabilities from the FDIC of Gulf State Community Bank Acquired approximately $112 million in assets & assumed approximately $100 million in deposits Loss share protection on approximately $70 million of covered loans and approximately $10 million of covered foreclosed assets Consumer loans of approximately $4 million are not covered under the loss sharing agreement Acquired branches will operate as Centennial Bank, a wholly-owned subsidiary of Home BancShares, Inc. Branches normally open on Saturday will be open under regular business hours on Saturday, November 20

Florida Panhandle Presence Eastpoint (1+2) Apalachicola Carrabelle (1+1) Port St. Joe (2) Lynn Haven Panama City (2) St. George Island (1+1) Panama City Beach Mexico Beach Southport Blountstown (2) Bristol Tallahassee (5) Panacea Crawfordville (3+1) Coastal-Bayside-Wakulla Acquisitions Gulf State Acquisition

Strategic Opportunity Additive to current Florida footprint Complements recent Panhandle transactions Coastal Community / Bayside Savings / Wakulla Bank Popular long-time vacation destination for many Arkansans Enhances franchise in Wakulla and Franklin counties Financially compelling transaction - immediately accretive to: Net income Earnings per share Book value Tangible book value Leverages a portion of our excess capital

Overview of Gulf State Established on January 6, 1971 5 full service locations in two Florida counties - Franklin and Wakulla Core funded franchise ranked #2 in aggregate market share across its counties of operations Source: Core deposits defined as total deposits less jumbo time deposits MRQ as of 9/30/10 Core Deposits ($mm) Acquired Gulf State Branches Existing Branches Pro Forma Panhandle Branch Network

Deposit Market Share Deposit Market Share (1) Gulf State ranked 2nd with aggregate market share of 22.1% in Franklin and Wakulla counties combined Ranked 2 in Franklin county and 3 Wakulla county On a pro forma basis, top 2 deposit market share in HOMB combined counties of operation in Florida panhandle Source: SNL Financial. Data as of 6/30/10 (1) Deposit market share for HOMB counties of operation in Florida Panhandle: Bay, Calhoun, Franklin, Gulf, Leon, Liberty, and Wakulla.

DDA NOW MM&S Retail Jumbo East 37 13 38 12 West 30.6 38.6 31 31.6 North 45.9 46.9 45 43.9 Deposit Composition DDA NOW MM&S Retail Jumbo East 8 41 20 31 West 30.6 38.6 31 31.6 North 45.9 46.9 45 43.9 DD NOW MM&S R J East 10 0 38 23 29 West 30.6 38.6 34.6 31.6 North 45.9 46.9 45 43.9 HOMB(1) Gulf State HOMB - Pro Forma (Dollars in Millions) HOMB(1) (9/30/2010) Acquired Deposits HOMB Pro Forma Transaction Accounts $ 298 $ 37 $ 335 Money Market & Savings 1,179 13 1,192 Retail Time Deposits 610 38 648 Jumbo Time Deposits 832 12 844 $ 2,919 $ 100 $ 3,019 29% 40% 21% 10% 12% 38% 21% 40% 11% Transaction Accounts Money Market & Savings Jumbo Time Deposits Retail Time Deposits 37% 13% 28% HOMB pro forma for previously announced acquisition of Wakulla Bank

Loan Composition Loan Type HOMB (2) (9/30/10) Acquired Amount (3) (9/30/10) HOMB Pro-forma Total % of Pro-forma Total Loans Commercial RE (Non-farm/non-residential & agri.) $ 1,023 $25 $1,048 39% Construction/Land Development 533 23 556 21% Residential Real Estate 623 19 642 24% Commercial & Industrial (1) 318 4 322 12% Consumer 57 3 60 2% Other 53 0 53 2% Total $ 2,607 $74 $2,681 100% Includes Agricultural HOMB pro forma for previously announced acquisition of Wakulla Bank Before loan discounts and FDIC receivables (Dollars in Millions)

FLORIDA Port Charlotte Punta Gorda Marco Island Key Largo Islamorada Marathon (2) Big Pine Key West (3) Summerland 47 Branches (As of November 2010) Orlando (2) Winter Park Longwood (2) Clermont Eastpoint (1+2) Apalachicola Carrabelle (1+1) Port St. Joe (2) Lynn Haven Panama City (2) St. George Island (1+1) Panama City Beach Mexico Beach Southport ' Blountstown (2) Bristol Tallahassee (5) Panacea Crawfordville (3+1) Florida Pro-Forma Footprint Branch Locations Acquired Branches Existing Branches Leon County, FL - 5 Wakulla County, FL 1 4 Calhoun County, FL - 2 Liberty County, FL - 1 Bay County, FL - 6 Franklin County, FL 4 4 Gulf County, FL - 2 Charlotte County, FL - 2 Collier County, FL - 1 Lake County, FL - 1 Monroe County, FL - 9 Orange County, FL - 3 Seminole County, FL - 2 Total 5 42 Acquired Branch Locations Existing Branch Locations

Florida Deposit Market Share Selected Markets Branch Count HOMB Pro-forma Deposits (6/30/10) Total Deposits in Market Deposit Market Share Rank Deposit Market Share % Franklin County, FL 8 $225 $264 1 85.2% Wakulla County, FL 5 196 259 1 75.8 Liberty County, FL 1 15 43 2 34.8 Gulf County, FL 2 68 226 2 30.3 Bay County, FL 6 229 2,403 3 9.5 Calhoun County, FL 2 20 135 4 15.0 Key West, FL MSA 9 296 2,258 4 13.1 Leon County, FL 5 172 5,089 10 3.4 Punta Gorda MSA 2 17 3,266 16 0.5 Lake County, FL 1 55 4,783 17 1.2 Orange County, FL 3 120 21,972 19 0.6 Seminole County, FL 2 41 6,125 26 0.7 Naples - Marco Island MSA 1 24 11,056 36 0.2 (Dollars in Millions) Source: FDIC as of 6/30/10 Home BancShares Inc. Pro-Forma

Historical Acquisitions Year Acquired Bank Location Assets ($mm) 2003 Community Bank Cabot, AR $326 2005 Twin City Bank North Little Rock, AR $633 2005 Marine Bank Marathon, FL $258 2005 Bank of Mountain View Mountain View, AR $203 2008 Centennial Bank Little Rock, AR $234 2010 Old Southern Bank Orlando, FL $335 2010 Key West Bank Key West, FL $97 2010 Coastal Community Bank Panama City, FL $362 2010 Bayside Savings Bank Port Saint Joe, FL $63 2010 Wakulla Bank Crawfordville, FL $353

Florida Tallahassee Jacksonville Orlando Miami Tampa Potential Future Opportunities Potential Opportunity Total Institutions: 53 Total Assets: $17.0bn Median Age: 11 years Potential Opportunities Asset Size Distribution Source: SNL Financial Includes regulated depositories headquartered in Florida with assets less than $2.0 billion and Texas Ratio greater than 100% as of 9/30/2010. City

Conclusion Enhances Florida franchise Acquisition provides scale in Florida Panhandle Logical extension of existing HOMB franchise Financially attractive transaction Accretive to earnings, book value, tangible book value with conservative assumptions Acquisition is consistent with HOMB's operating strategy Stable core deposit base in Arkansas enhanced by higher-growth Florida markets Seamless integration expected HOMB has formed a dedicated team to lead the integration process for its FDIC-Assisted transactions in Florida

Contact Information Corporate Headquarters Home BancShares, Inc. 719 Harkrider St., Suite 100 P.O. Box 966 Conway, AR 72033 Financial Information Randy Mayor Chief Financial Officer (501) 472-1849 rmayor@homebancshares.com Website www.homebancshares.com

FDIC-Assisted Acquisition Gulf State Community Bank November 19, 2010 NASDAQ: HOMB www.homebancshares.com