Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

Audit Committee, Board of Directors and Stockholders
Home BancShares, Inc.
Conway, Arkansas

We consent to the incorporation by reference in the Registration Statements on Forms S-8 (Nos. 333-136645, 333-148763 and 333-151843) and Forms S-3 (Nos. 333-157165, 333-161198 and 333-164341) of our report dated May 21, 2010, on our audit of the statement of assets acquired and liabilities assumed by Centennial Bank (a wholly owned subsidiary of Home BancShares, Inc., Inc.) pursuant to the purchase and assumption agreement dated March 12, 2010 and included in this Form 8-K/A.

/s/ BKD, LLP  

Little Rock, Arkansas
May 21, 2010