Exhibit 15.1

Awareness of Independent Registered
Public Accounting Firm

We are aware that our reports dated May 6, 2009 and August 5, 2009, included with the Quarterly Report on Form 10-Q for the quarters ended March 31, 2009 and June 30, 2009, respectively, are incorporated by reference in this registration statement of Home BancShares, Inc. on Form S-3. Pursuant to Rule 436(c) under the Securities Act of 1933, these reports should not be considered a part of the registration statement prepared or certified by us within the meaning of Sections 7 and 11 of that Act.

/s/ BKD, LLP  

Little Rock, Arkansas
August 10, 2009