ADAMAS PHARMACEUTICALS, INC.

1900 Powell Street, Suite 1000

Emeryville, CA 94608

(510) 450-3500

November 25, 2019

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attn: Ada D. Sarmento

Joe McCann

RE: Adamas Pharmaceuticals, Inc.
Registration Statement on Form S-3
File No. 333-234570

Ladies and Gentlemen:

Adamas Pharmaceuticals, Inc. hereby requests that the Securities and Exchange Commission take appropriate action to cause the above-referenced Registration Statement on Form S-3 to become effective on December 2, 2019, at 4:00 p.m., Eastern Time, or as soon thereafter as is practicable.

Very truly yours,

Adamas Pharmaceuticals, Inc.

By: /s/ Christopher B. Prentiss     Christopher B. Prentiss

Chief Financial Officer