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Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity - USD ($)
Total
Public Offering [Member]
Series B Redeemable Convertible Preferred Stock [Member]
Common Stock [Member]
Common Stock [Member]
Public Offering [Member]
Additional Paid-In Capital [Member]
Additional Paid-In Capital [Member]
Public Offering [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Loss [Member]
Beginning Balance at Dec. 31, 2017 $ 39,395,823     $ 61   $ 121,657,587   $ (77,684,839) $ (4,576,986)
Beginning Balance (in shares) at Dec. 31, 2017     12,177            
Beginning Balance at Dec. 31, 2017     $ 9,281,767            
Beginning Balance (in shares) at Dec. 31, 2017       608,499          
Stock based compensation 762,162         762,162      
Vesting and accelerated vesting of restricted stock, net 11,203         11,203      
Vesting and accelerated vesting of restricted stock, net (in shares)       284          
Exercises of stock options 22,898     $ 1   22,897      
Exercises of stock options (in shares)       9,540          
Accretion of Series B redeemable convertible preferred stock (2,894,885)         (2,894,885)      
Accretion of Series B redeemable convertible preferred stock     $ 2,894,885            
Conversion of Series B redeemable convertible preferred stock into common stock 9,790,367     $ 50   9,790,317      
Conversion of Series B redeemable convertible preferred stock into common stock (in shares)     (9,813)            
Conversion of Series B redeemable convertible preferred stock into common stock     $ (9,790,367)            
Conversion of Series B redeemable convertible preferred stock into common stock (in shares)       502,078          
Redemption of Series B redeemable convertible preferred stock for cash and release of embedded derivative 23,292         23,292      
Redemption of Series B redeemable convertible preferred stock for cash and release of embedded derivative (in shares)     (2,364)            
Redemption of Series B redeemable convertible preferred stock for cash and release of embedded derivative     $ (2,386,285)            
Issuance of common stock for the exchange of warrants 3,433,041     $ 32   3,433,009      
Issuance of common stock for the exchange of warrants (in shares)       318,668          
Issuance of common stock and units, net of offerings cost 26,735,488 $ 10,667,506   $ 491 $ 241 26,734,997 $ 10,667,265    
Issuance of common stock and units, net of offering costs (in shares)       4,916,263 2,400,000        
Foreign currency translation adjustments (463,177)               (463,177)
Net loss (39,171,152)             (39,171,152)  
Ending Balance at Dec. 31, 2018 48,312,566     $ 876   170,207,844   (116,855,991) (5,040,163)
Ending Balance (in shares) at Dec. 31, 2018       9,078,238          
Stock based compensation 1,264,231         1,264,231      
Vesting and accelerated vesting of restricted stock, net (47,120)     $ 6   (47,126)      
Vesting and accelerated vesting of restricted stock, net (in shares)       (25,691)          
Issuance of common stock upon exercise of warrants 30,324     $ 1   30,323      
Issuance of common stock upon exercise of warrants (in shares)       11,000          
Issuance of common stock and units, net of offerings cost 12,668,784     $ 436   12,668,348      
Issuance of common stock and units, net of offering costs (in shares)       4,361,370          
Issuance of common stock for acquired in-process research and development 3,791,485     $ 189   3,791,296      
Issuance of common stock for acquired in-process research and development (in shares)       1,887,250          
Unrealized gain on short term investments 20,007               20,007
Net loss (20,520,131)             (20,520,131)  
Ending Balance at Dec. 31, 2019 $ 45,520,146     $ 1,508   $ 187,914,916   $ (137,376,122) $ (5,020,156)
Ending Balance (in shares) at Dec. 31, 2019       15,312,167