CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)	3 Months Ended
	Mar. 31, 2012	Mar. 31, 2011
Revenue	$ 6,149,052	$ 6,337,722
Operating expenses:
Research and development	4,705,357	5,820,374
General and administrative	2,948,481	4,939,654
Depreciation and amortization	85,910	117,629
Total operating expenses	7,739,748	10,877,657
Loss from operations	(1,590,696)	(4,539,935)
Other income (expense):
Interest income	2,988	3,154
Interest expense	(3,028)	(15,435)
Other income (expense)	52,915	(11,906)
Change in fair value of derivative instruments	(991,662)	2,488,465
Total other income (expense)	(938,787)	2,464,278
Net loss before income taxes	(2,529,483)	(2,075,657)
Income tax expense	(150,405)
Net loss	$ (2,679,888)	$ (2,075,657)
Basic and diluted net loss per share	$ (0.06)	$ (0.04)
Weighted average shares used in calculation of basic and diluted net loss per share	48,269,894	46,276,874