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Description of Business and Basis of Presentation - Additional Information (Detail) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Jan. 01, 2016
Dec. 31, 2015
Organization Consolidation And Presentation Of Financial Statements [Abstract]        
Accumulated deficit $ (358,876)   $ 31,000 $ (250,376)
Net cash used in operating activities $ (27,840) $ (14,361)