UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

(Rule 14a-101)

INFORMATION REQUIRED IN PROXY STATEMENT

SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

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☐ Preliminary Proxy Statement

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☐ Definitive Proxy Statement

☒ Definitive Additional Materials

☐ Soliciting Material Pursuant to §240.14a-12

AVEO PHARMACEUTICALS, INC.

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than The Registrant)

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☐ Preliminary Proxy Statement

****IMPORTANT REMINDER****

Dear Fellow AVEO Stockholder:

Our Special Meeting of Stockholders is scheduled to be held on February 13, 2020. You are receiving this reminder letter because your votes were not yet processed at the time this letter was mailed.

We urge you to submit your vote TODAY.

Each stockholder’s vote is extremely important no matter how many shares you own. Your Board of Directors strongly recommends that you vote your shares FOR the Reverse Stock Split proposal, which is being proposed to facilitate our ability to regain compliance with Nasdaq’s minimum bid price requirements so as to maintain our listing on Nasdaq. This proposal requires a majority of the outstanding shares of AVEO common stock voting in favor to pass, so every vote is important.

PLEASE VOTE TODAY

The fastest and easiest way to vote is by telephone or over the Internet. Instructions on how to vote your shares over the telephone or Internet are enclosed with this letter. Alternatively, you may sign and return the enclosed voting form in the envelope provided.

If you have questions or need help voting your shares, please call our proxy solicitation firm, Morrow Sodali LLC, at 1-800-607-0088.

Thank you for your investment in AVEO and taking the time to vote your shares.

Sincerely,

Michael P. Bailey

President and Chief Executive Officer