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Note 15 - Right-of-use Assets - Right-of-use Assets (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Opening balance for the year $ 134,914
Initial recognition of operating lease right-of-use assets 76,557
Capitalization of operating lease right-of-use assets 125,474
Amortization of operating lease right-of use assets (54,071) (72,416)
Closing balance for the year 106,315 134,914
Facility in Vancouver, Canada [Member]    
Capitalization of operating lease right-of-use assets 125,474
Operating Lease, License Agreement [Member]    
Capitalization of operating lease right-of-use assets $ 25,472 $ 5,299