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Note 13 - Right-of-use Assets - Right-of-use Assets (Details) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Operating lease right-of-use assets     $ 134,914
Initial recognition of operating lease right-of-use assets       76,557
Capitalization of operating lease right-of-use assets       125,474
Amortization of operating lease right-of use assets $ (15,734) $ (20,972) (44,695) $ (58,475) (72,416)
Operating lease right-of-use assets $ 107,318   107,318   134,914
Facility in Vancouver, Canada [Member]          
Capitalization of operating lease right-of-use assets       125,474
Operating Lease, License Agreement [Member]          
Capitalization of operating lease right-of-use assets     $ 17,099   $ 5,299