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Note 13 - Right-of-use Assets - Right-of-use Assets (Details) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2019
Operating lease right-of-use assets     $ 134,914
Initial recognition of operating lease right-of-use assets       76,557
Capitalization of operating lease right-of-use assets       125,474
Amortization of operating lease right-of use assets $ (13,589) $ (24,943) (28,961) $ (37,503) (72,416)
Operating lease right-of-use assets $ 114,621   114,621   134,914
Facility in Vancouver, Canada [Member]          
Capitalization of operating lease right-of-use assets       125,474
Operating Lease, License Agreement [Member]          
Capitalization of operating lease right-of-use assets     $ 8,668   $ 5,299