The total amount of development costs accumulated over the course of development.

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- Definition

Fair value, after the effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities not subject to a master netting arrangement and not elected to be offset.

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- Definition

Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Amount of expense (income) related to adjustment to fair value of warrant liability.

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Value of input used to measure long-term debt.

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Note 2 - Summary of Significant Accounting Policies (Details Textual)	3 Months Ended		12 Months Ended
	Mar. 31, 2018 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2018	Dec. 31, 2017 USD ($)	Jun. 16, 2017 USD ($)	Dec. 31, 2016 USD ($)
Accumulated Development Costs	$ 6,039,095	$ 5,149,769		$ 5,768,476		$ 4,935,274
Derivative Liability, Total	215,687				$ 215,687
Fair Value Adjustment of Warrants	$ 171,115
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent				34.00%
Scenario, Forecast [Member]
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent			21.00%
Promissory Note [Member] \| Valuation, Income Approach [Member] \| Measurement Input, Discount Rate [Member]
Long-term Debt, Measurement Input	15