Exhibit 32.1

CERTIFICATION PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Each of the undersigned officers of American CareSource Holdings, Inc. (the “Company”), certifies that:

(1) the Quarterly Report on Form 10-QSB of the Company for the three month periods ended June 30, 2006 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. 78m or 78o(d)); and

(2) the information contained in the Quarterly Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date:	November 14, 2006	By:	/s/ Wayne A. Schellhammer
			Wayne A. Schellhammer Chief Executive Officer
Date:	November 14, 2006	By:	/s/ David S. Boone
			David S. Boone Chief Operating Officer and Chief Financial Officer
Date:	November 14, 2006	By:	/s/ Steven M. Phillips
			Steven M. Phillips Controller and Principal Accounting Officer

This certification is made solely for the purpose of 18 U.S.C. Section 1350, subject to the knowledge standard contained therein, and not for any other purpose.