8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported)  October 22, 2008

AMERICAN CARESOURCE HOLDINGS, INC.

(Exact name of Registrant as specified in its charter)

Delaware (State or Other Jurisdiction
of Incorporation) 001-33094 (Commission File Number) 20-0428568 (IRS Employer Identification No.)

5429 Lyndon B. Johnson Freeway, Suite 700, Dallas, Texas	75240
(Address of Principal Executive Offices)	(Zip Code)

Registrant’s telephone number, including area code (972) 308-6830

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the Registrant under any of the following provisions (see General Instruction A.2.):

o           Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o           Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o           Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 ITEM 2.02 Results of Operations and Financial Condition.

On October 22, 2008, American CareSource Holdings, Inc. (the “Registrant”) issued a press release announcing its revenues for the quarter ended September 30, 2008.  A copy of the press release is attached hereto as Exhibit 99.1.

In accordance with General Instruction B.2 of Form 8-K, the information in this Current Report on Form 8-K, including the exhibit attached hereto, is furnished under Item 2.02 - “Results of Operations and Financial Condition.”  The information presented herein, including the exhibit attached hereto, shall not be deemed to be “filed” for any purpose, including for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section.  The information in this Current Report on Form 8-K shall not be deemed incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

ITEM 9.01    Financial Statements and Exhibits.

 (d)           Exhibits

This exhibit is furnished pursuant to Item 2.02 and shall not be deemed “filed.”

99.1 Press release of Registrant, dated October 22, 2008

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	AMERICAN CARESOURCE HOLDINGS, INC.
Date: October 24, 2008	By:	/s/ Matthew D. Thompson
		Matthew D. Thompson
		Principal Accounting Officer and Controller

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EX-99.1

Exhibit 99.1

Contact:

Steven J. Armond

Chief Financial Officer

American CareSource Holdings, Inc.

Tel: 972-308-6847

FOR IMMEDIATE RELEASE

AMERICAN CARESOURCE HOLDINGS REPORTS 127% INCREASE IN REVENUES

FOR THIRD QUARTER 2008

– Company Reports Six Consecutive Quarters of Revenue Growth –

DALLAS, TX – October 22, 2008 - -- American CareSource Holdings, Inc. (Nasdaq: ANCI) today reported a 127% increase in revenues to approximately $16.1 million for the third quarter ended September 30, 2008 compared to approximately $7.1 million in the same period last year.  The Company’s third quarter revenues also represent a 24% improvement over second quarter 2008 reported revenues of $13.0 million.  For the nine months ended September 30, 2008, the Company reported a 204% improvement in revenues to approximately $40.6 million compared to the same period in 2007.

“The 2008 third quarter results represent our sixth consecutive quarter of record revenue expansion,” stated David S. Boone, Chief Executive Officer of American CareSource.  “This reflects the enormous opportunity in the market for us to pursue and confirms our organization’s ability to execute against that growth potential.  New technology and continued medical cost containment pressure are helping drive more ancillary care services to be performed in alternate settings.  We believe that our network of high quality, cost effective ancillary care service providers will play an important role in containing overall healthcare costs.”

American CareSource will host a conference call to discuss the third quarter financial results on Thursday, November 13, 2008 at 10:00 a.m. central time.  The Company will issue a press release reporting full financial results the same morning.

About Ancillary Healthcare Services

American CareSource provides ancillary healthcare services through its network that offers cost effective alternatives to physician and hospital-based services. This market is estimated at $574 billion, and has grown to 30% of total national health expenditures. These providers offer services in over 30 categories, including laboratories, dialysis centers, free-standing diagnostic imaging centers, non-hospital surgery centers, as well as durable medical equipment such as orthotics and prosthetics, and others.

About American CareSource Holdings, Inc.

American CareSource Holdings, the first national, publicly traded ancillary care network services company, offers a comprehensive national network of approximately 2,500 ancillary service providers at over 25,000 sites. The Company's ancillary network and management provides a complete outsourced solution for a wide variety of healthcare payors and plan sponsors including self-insured employers, indemnity insurers, PPOs, HMOs, third party administrators and both federal and local governments. For additional information, please visit www.anci-care.com.

Safe Harbor Statement Under the Private Securities Litigation Reform Act of 1995:

Any statements that are not historical facts contained in this release are forward-looking statements. It is possible that the assumptions made by American CareSource Holdings, Inc. for purposes of such statements may not materialize. Actual results may differ materially from those projected or implied in any forward-looking statements. Such statements may involve further risks and uncertainties, including but not limited to those relating to demand for our services, pricing, market acceptance, timing, issues relating to client implementation and  the effect of economic conditions, competition and other risks identified in this release, and the Securities and Exchange Commission filings of American CareSource Holdings, Inc.

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