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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 caVbZY0NNgLVTfCuQ78tHg==

<SEC-DOCUMENT>0001193805-05-002538.txt : 20060906
<SEC-HEADER>0001193805-05-002538.hdr.sgml : 20060906
<ACCEPTANCE-DATETIME>20051214164056
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0001193805-05-002538
CONFORMED SUBMISSION TYPE:	CORRESP
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20051214

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			American Caresource Holdings, Inc.
		CENTRAL INDEX KEY:			0001316645
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
		IRS NUMBER:				200428568
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		CORRESP

	BUSINESS ADDRESS:	
		STREET 1:		8080 TRISTAR DRIVE
		STREET 2:		SUITE 100
		CITY:			IRVING
		STATE:			TX
		ZIP:			75063
		BUSINESS PHONE:		972-871-7912

	MAIL ADDRESS:	
		STREET 1:		8080 TRISTAR DRIVE
		STREET 2:		SUITE 100
		CITY:			IRVING
		STATE:			TX
		ZIP:			75063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	American Caresouce Holdings, Inc.
		DATE OF NAME CHANGE:	20050204
</SEC-HEADER>
<DOCUMENT>
<TYPE>CORRESP
<SEQUENCE>1
<FILENAME>filename1.txt
<TEXT>

                       AMERICAN CARESOURCE HOLDINGS, INC.
                               8080 Tristar Drive
                               Irving, Texas 75063

                                                               December 14, 2005

Re: American Caresource Holdings, Inc.
    Registration Statement on Form SB-2 (File No. 333-122820)

U.S. Securities and Exchange Commission
Division of Corporate Finance
450 Fifth Street, N.W.
Washington, D.C. 20549
Attn:  David Roberts

Dear Mr. Roberts:

      Pursuant to Rule 461 under the Securities Act of 1933, as amended,
American Caresource Holdings, Inc. hereby requests that the effective date of
the above-referenced Registration Statement be accelerated so that the
Registration Statement may become effective at 4:00 PM Eastern time on Thursday,
December 15, 2005 or as soon as practicable thereafter.

                                              AMERICAN CARESOURCE HOLDINGS, INC.


                                              By: /s/ David S. Boone
                                                  ------------------------------
                                              Name:  David S. Boone
                                              Title: Chief Financial Officer
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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