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Warrants - Additional Information (Detail) (USD $)
1 Months Ended 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Apr. 30, 2012
Dec. 31, 2009
Dec. 31, 2005
Dec. 31, 2004
Class of Warrant or Right [Line Items]              
Number of common shares can purchased from outstanding warrants 35,778     25,000   284,378 26,946
Weighted-average exercise price of warrants 4.84     6.84   3.52 0.20
Series C-1 preferred stock issued upon warrant exercise     283,223        
Warrants expired unexercised     1,155        
Warrants to purchase of common shares with extended expiration date             10,778
Prepaid fees         $ 26,519    
Issued common shares with cashless exercise of warrants   15,446          
Prepaid fees to be expensed over two years       219,000      
Common shares issued upon net exchange of warrants $ 24,955