0001752724-23-191187.txt : 20230825 0001752724-23-191187.hdr.sgml : 20230825 20230825143758 ACCESSION NUMBER: 0001752724-23-191187 CONFORMED SUBMISSION TYPE: NPORT-P PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20230630 FILED AS OF DATE: 20230825 DATE AS OF CHANGE: 20230825 PERIOD START: 20231231 FILER: COMPANY DATA: COMPANY CONFORMED NAME: BlackRock Health Sciences Trust CENTRAL INDEX KEY: 0001314966 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: NPORT-P SEC ACT: 1940 Act SEC FILE NUMBER: 811-21702 FILM NUMBER: 231207001 BUSINESS ADDRESS: STREET 1: 100 BELLEVUE PARKWAY CITY: WILMINGTON STATE: DE ZIP: 19809 BUSINESS PHONE: (888) 825-2257 MAIL ADDRESS: STREET 1: 100 BELLEVUE PARKWAY CITY: WILMINGTON STATE: DE ZIP: 19809 NPORT-P 1 primary_doc.xml NPORT-P false 0001314966 XXXXXXXX BlackRock Health Sciences Trust 811-21702 0001314966 4UL0KI4EPYFKMUU31I34 100 BELLEVUE PARKWAY WILMINGTON 19809 800-441-7762 BlackRock Health Sciences Trust 4UL0KI4EPYFKMUU31I34 2023-12-31 2023-06-30 N 616559095.54 19305860.21 597253235.33 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 N MSCI USA IMI Health Care Call Overwrite Index N/A Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -8447.50000000 -0.00141439166 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Morphic Holding, Inc. 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HCA Healthcare, Inc. 100.00000000 285.00000000 USD 2023-07-21 XXXX -43331.41000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -54.00000000 NC USD -4050.00000000 -0.00067810432 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rhythm Pharmaceuticals, Inc. Rhythm Pharmaceuticals, Inc. 100.00000000 22.50000000 USD 2023-07-21 XXXX 520.32000000 N N N Frequency Therapeutics Inc N/A 35803L108 28060.00000000 NS USD 9708.76000000 0.001625568423 Long EC CORP US N 1 N N N Agiliti Inc N/A 00848J104 40496.00000000 NS USD 668184.00000000 0.111876162484 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -11.00000000 NC USD -3602.50000000 -0.00060317797 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Humana, Inc. Humana, Inc. 100.00000000 470.00000000 USD 2023-07-28 XXXX 3332.05000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -60.00000000 NC USD -55200.00000000 -0.00924231075 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Blueprint Medicines Corp. Blueprint Medicines Corp. 100.00000000 55.00000000 USD 2023-07-21 XXXX -32533.93000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -21.00000000 NC USD -2165.33000000 -0.00036254805 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written ResMed, Inc. ResMed, Inc. 100.00000000 234.21000000 USD 2023-07-21 XXXX 16099.71000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -126.00000000 NC USD -78120.00000000 -0.01307987891 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Danaher Corp. 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Danaher Corp. 100.00000000 240.00000000 USD 2023-08-04 XXXX -5100.91000000 N N N PMV Pharmaceuticals Inc N/A 69353Y103 17490.00000000 NS USD 109487.40000000 0.018331822001 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -43.00000000 NC USD -1505.00000000 -0.00025198691 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Sage Therapeutics, Inc. Sage Therapeutics, Inc. 100.00000000 52.50000000 USD 2023-07-21 XXXX 14223.02000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -3.00000000 NC USD -1845.00000000 -0.00030891419 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 190.00000000 USD 2023-08-04 XXXX -658.13000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -14.00000000 NC USD -27393.90000000 -0.00458664740 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Stryker Corp. Stryker Corp. 100.00000000 292.00000000 USD 2023-08-18 XXXX -19431.18000000 N N N GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 000000000 -4700.00000000 NC -10514.23000000 -0.00176043081 N/A DE US N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 Call Written Sanofi Sanofi 1.00000000 97.09270000 EUR 2023-07-18 XXXX -2986.57000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -115.00000000 NC USD -8165.00000000 -0.00136709179 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AbbVie, Inc. AbbVie, Inc. 100.00000000 140.00000000 USD 2023-07-28 XXXX 23520.34000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -21.00000000 NC USD -26145.00000000 -0.00437754012 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Inspire Medical Systems, Inc. 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Mettler-Toledo International, Inc. 100.00000000 1385.00000000 USD 2023-08-18 XXXX 2957.80000000 N N N CITIBANK NA E57ODZWZ7FF32TWEFA76 000000000 -5900.00000000 NC USD -5196.07000000 -0.00086999445 N/A DE US N 2 CITIBANK NA E57ODZWZ7FF32TWEFA76 Call Written Alkermes PLC Alkermes PLC 1.00000000 33.63000000 USD 2023-08-29 XXXX 6063.49000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -52.00000000 NC USD -1170.00000000 -0.00019589680 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written BioMarin Pharmaceutical, Inc. BioMarin Pharmaceutical, Inc. 100.00000000 100.00000000 USD 2023-07-21 XXXX 18039.47000000 N N N Nucleix Limited, SERIES AA N/A 000000000 367395.00000000 NS USD 1142598.45000000 0.191308875768 Long EP CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -33.00000000 NC USD -9900.00000000 -0.00165758834 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Repligen Corp. 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UnitedHealth Group, Inc. 100.00000000 485.00000000 USD 2023-07-07 XXXX 205241.48000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -118.00000000 NC USD -4130.00000000 -0.00069149897 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Amgen, Inc. Amgen, Inc. 100.00000000 235.00000000 USD 2023-07-21 XXXX 29583.19000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -30.00000000 NC USD -61050.00000000 -0.01022179477 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written HCA Healthcare, Inc. HCA Healthcare, Inc. 100.00000000 290.00000000 USD 2023-08-18 XXXX -32102.61000000 N N N Genmab A/S 529900MTJPDPE4MHJ122 000000000 2498.00000000 NS 946636.35000000 0.158498320980 Long EC CORP DK N 2 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -113.00000000 NC USD -6723.50000000 -0.00112573689 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Amgen, Inc. Amgen, Inc. 100.00000000 235.00000000 USD 2023-07-28 XXXX 28296.58000000 N N N Roche Holding AG 549300U41AUUVOAAOB37 000000000 11601.00000000 NS 3543756.37000000 0.593342347997 Long EC CORP CH N 2 N N N Zoetis Inc 549300HD9Q1LOC9KLJ48 98978V103 61919.00000000 NS USD 10663070.99000000 1.785351733441 Long EC CORP US N 1 N N N Boston Scientific Corp Y6ZDD9FP4P8JSSJMW954 101137107 447569.00000000 NS USD 24209007.21000000 4.053390719034 Long EC CORP US N 1 N N N Zimmer Biomet Holdings Inc 2P2YLDVPES3BXQ1FRB91 98956P102 14617.00000000 NS USD 2128235.20000000 0.356337157189 Long EC CORP US N 1 N N N ResMed Inc 529900T3QE5253CCXF22 761152107 13234.00000000 NS USD 2891629.00000000 0.484154597907 Long EC CORP US N 1 N N N Elevance Health Inc 8MYN82XMYQH89CTMTH67 036752103 12737.00000000 NS USD 5658921.73000000 0.947491180499 Long EC CORP US N 1 N N N Apellis Pharmaceuticals Inc 254900HS0ZFRXXSB9D42 03753U106 13695.00000000 NS USD 1247614.50000000 0.208892045483 Long EC CORP US N 1 N N N Biogen Inc W8J5WZB5IY3K0NDQT671 09062X103 38487.00000000 NS USD 10963021.95000000 1.835573472271 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -123.00000000 NC USD -153750.00000000 -0.02574284924 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Eli Lilly & Co. Eli Lilly & Co. 100.00000000 460.00000000 USD 2023-07-14 XXXX -60117.35000000 N N N Inspire Medical Systems Inc 549300XQQCQ7HCJKTW25 457730109 5650.00000000 NS USD 1834216.00000000 0.307108591715 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -83600.00000000 -0.01399741266 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written McKesson Corp. McKesson Corp. 100.00000000 390.00000000 USD 2023-07-07 XXXX -63889.70000000 N N N CONTRA ABIOMED INC N/A 003CVR016 14359.00000000 NS USD 40492.38000000 0.006779767375 Long CORP US N 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -38.00000000 NC USD -2185.00000000 -0.00036584146 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written REVOLUTION Medicines, Inc. REVOLUTION Medicines, Inc. 100.00000000 30.00000000 USD 2023-07-21 XXXX 1850.22000000 N N N Daiichi Sankyo Co Ltd 353800XGIU2IHQGC9504 000000000 33900.00000000 NS 1077147.37000000 0.180350194236 Long EC CORP JP N 2 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -27.00000000 NC USD -53595.00000000 -0.00897358052 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written IDEXX Laboratories, Inc. IDEXX Laboratories, Inc. 100.00000000 490.00000000 USD 2023-07-21 XXXX -32396.61000000 N N N Nuvation Bio Inc N/A 67080N119 4050.00000000 NS USD 669.87000000 0.000112158454 N/A DE US N 1 N/A N/A Call Purchased Nuvation Bio Inc Nuvation Bio Inc 1.00000000 11.50000000 USD 2027-07-07 XXXX -7386.91000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -63.00000000 NC USD -764.25000000 -0.00012796079 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written iShares MSCI India ETF iShares MSCI India ETF 100.00000000 68.00000000 USD 2023-07-21 XXXX 9931.23000000 N N N Insulet Corp 549300TZTYD2PYN92D43 45784P101 8555.00000000 NS USD 2466748.70000000 0.413015544174 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -55.00000000 NC USD -13200.00000000 -0.00221011778 N/A DE GB N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Abcam PLC Abcam PLC 100.00000000 25.00000000 USD 2023-08-18 XXXX -6447.66000000 N N N Align Technology Inc 549300N5YSE0U3LCP840 016255101 5235.00000000 NS USD 1851305.40000000 0.309969924060 Long EC CORP US N 1 N N N Viking Therapeutics Inc 529900IVC72YPFA25M37 92686J106 16970.00000000 NS USD 275083.70000000 0.046058134762 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -44.00000000 NC USD -7810.00000000 -0.00130765302 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Neurocrine Biosciences, Inc. Neurocrine Biosciences, Inc. 100.00000000 105.00000000 USD 2023-08-18 XXXX 4807.89000000 N N N Becton Dickinson & Co ICE2EP6D98PQUILVRZ91 075887109 40270.00000000 NS USD 10631682.70000000 1.780096292676 Long EC CORP US N 1 N N N Penumbra Inc 549300RGE06P3ECANU72 70975L107 17840.00000000 NS USD 6138030.40000000 1.027709861899 Long EC CORP US N 1 N N N REVOLUTION Medicines Inc 549300JU3X0LBCQ65892 76155X100 18874.00000000 NS USD 504879.50000000 0.084533573053 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -245.00000000 NC USD -126175.00000000 -0.02112587969 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Abbott Laboratories Abbott Laboratories 100.00000000 104.00000000 USD 2023-07-07 XXXX -92421.40000000 N N N IQVIA Holdings Inc 549300W3R20NM4KQPH86 46266C105 26058.00000000 NS USD 5857056.66000000 0.980665539093 Long EC CORP US N 1 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -22.00000000 NC USD -3676.05000000 -0.00061549268 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Alkermes PLC Alkermes PLC 100.00000000 30.25000000 USD 2023-07-25 XXXX -1052.12000000 N N N Moderna Inc 549300EI6OKH5K5Q2G38 60770K107 15623.00000000 NS USD 1898194.50000000 0.317820714516 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -194.00000000 NC USD -64020.00000000 -0.01071907127 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 42.50000000 USD 2023-07-21 XXXX -51454.55000000 N N N Stryker Corp 5493002F0SC4JTBU5137 863667101 68196.00000000 NS USD 20805917.64000000 3.483600658689 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -3520.00000000 -0.00058936474 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Neurocrine Biosciences, Inc. Neurocrine Biosciences, Inc. 100.00000000 100.00000000 USD 2023-07-21 XXXX 3764.83000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -12090.00000000 -0.00202426697 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Regeneron Pharmaceuticals, Inc. Regeneron Pharmaceuticals, Inc. 100.00000000 800.00000000 USD 2023-08-18 XXXX 57678.25000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -107.00000000 NC USD -12037.50000000 -0.00201547673 N/A DE CA N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bausch & Lomb Corp. Bausch & Lomb Corp. 100.00000000 20.00000000 USD 2023-08-18 XXXX 242.88000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -79.00000000 NC USD -987.50000000 -0.00016534025 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Ionis Pharmaceuticals, Inc. Ionis Pharmaceuticals, Inc. 100.00000000 45.00000000 USD 2023-07-21 XXXX 2865.37000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -8.00000000 NC USD -2080.00000000 -0.00034826098 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written iRhythm Technologies, Inc. iRhythm Technologies, Inc. 100.00000000 120.00000000 USD 2023-08-18 XXXX 646.66000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -107.00000000 NC USD -10386.92000000 -0.00173911489 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Bausch & Lomb Corp. Bausch & Lomb Corp. 100.00000000 19.63000000 USD 2023-07-21 XXXX -2196.49000000 N N N ImmunoGen Inc 54930084U0R1OP766Y02 45253H101 18174.00000000 NS USD 342943.38000000 0.057420095817 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -31520.00000000 -0.00527749338 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written McKesson Corp. McKesson Corp. 100.00000000 425.00000000 USD 2023-07-28 XXXX -10409.85000000 N N N Cigna Group/The 549300VIWYMSIGT1U456 125523100 22809.00000000 NS USD 6400205.40000000 1.071606652153 Long EC CORP US N 1 N N N Structure Therapeutics Inc N/A 86366E106 13208.00000000 NS USD 549056.56000000 0.091930278066 Long EC CORP KY N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -2990.00000000 -0.00050062516 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 47.00000000 USD 2023-08-04 XXXX -447.99000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -149.00000000 NC USD -5960.00000000 -0.00099790166 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Avantor, Inc. Avantor, Inc. 100.00000000 22.50000000 USD 2023-08-18 XXXX 3243.79000000 N N N Illumina Inc SQ95QG8SR5Q56LSNF682 452327109 11735.00000000 NS USD 2200195.15000000 0.368385639432 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -58.00000000 NC USD -126730.00000000 -0.02121880510 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 330.00000000 USD 2023-08-18 XXXX -35502.50000000 N N N UBS AG BFM8T61CT2L1QCEMIK50 000000000 -5400.00000000 NC USD -17329.41000000 -0.00290151797 N/A DE US N 2 UBS AG BFM8T61CT2L1QCEMIK50 Call Written Legend Biotech Corp. Legend Biotech Corp. 1.00000000 75.79400000 USD 2023-09-08 XXXX 3773.79000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -29.00000000 NC USD -2682.50000000 -0.00044913946 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alnylam Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. 100.00000000 210.00000000 USD 2023-07-21 XXXX 14136.39000000 N N N Mirati Therapeutics Inc 529900GYRW59IDQV6N54 60468T105 15380.00000000 NS USD 555679.40000000 0.093039161134 Long EC CORP US N 1 N N N CITIBANK NA E57ODZWZ7FF32TWEFA76 000000000 -3300.00000000 NC USD -8100.77000000 -0.00135633756 N/A DE US N 2 CITIBANK NA E57ODZWZ7FF32TWEFA76 Call Written REVOLUTION Medicines, Inc. REVOLUTION Medicines, Inc. 1.00000000 25.25200000 USD 2023-07-31 XXXX -2733.98000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -33.00000000 NC USD -3465.00000000 -0.00058015591 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rocket Pharmaceuticals, Inc. Rocket Pharmaceuticals, Inc. 100.00000000 25.00000000 USD 2023-07-21 XXXX -768.33000000 N N N Orchestra BioMed Holdings Inc N/A 68572M106 13696.00000000 NS USD 95872.00000000 0.016052152475 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -15.00000000 NC USD -58275.00000000 -0.00975716773 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Align Technology, Inc. Align Technology, Inc. 100.00000000 315.00000000 USD 2023-07-07 XXXX -48089.78000000 N N N MoonLake Immunotherapeutics N/A 61559X104 15310.00000000 NS USD 780810.00000000 0.130733490220 Long EC CORP KY N 1 N N N Cerevel Therapeutics Holdings Inc 254900RJNIRS9COSQR41 15678U128 16785.00000000 NS USD 533595.15000000 0.089341525241 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -2.00000000 NC USD -490.00000000 -0.00008204225 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Mettler-Toledo International, Inc. Mettler-Toledo International, Inc. 100.00000000 1460.00000000 USD 2023-07-21 XXXX 5468.99000000 N N N GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 000000000 -4700.00000000 NC -7571.47000000 -0.00126771519 N/A DE US N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 Call Written Sanofi Sanofi 1.00000000 97.63140000 EUR 2023-07-13 XXXX -186.70000000 N N N Affinivax Inc., N/A 000000000 6331.00000000 NS USD 84898.71000000 0.014214859791 Long EC CORP US Y 3 N N N NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 000000000 -767.00000000 NC USD -116059.37000000 -0.01943218774 N/A DE US N 2 NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 Call Written Boston Scientific Corp. Boston Scientific Corp. 100.00000000 53.40000000 USD 2023-07-21 XXXX 35054.47000000 N N N Guardant Health Inc 254900M8C3E5VC8BR186 40131M109 12702.00000000 NS USD 454731.60000000 0.076137151395 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -37.00000000 NC USD -3052.50000000 -0.00051108973 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written 10X Genomics, Inc. 10X Genomics, Inc. 100.00000000 70.00000000 USD 2023-08-18 XXXX 2599.98000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -223.00000000 NC USD -104810.00000000 -0.01754867011 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merck & Co., Inc. Merck & Co., Inc. 100.00000000 112.00000000 USD 2023-07-28 XXXX -43692.83000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -65.00000000 NC USD -15145.00000000 -0.00253577529 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 87.00000000 USD 2023-07-28 XXXX -5880.45000000 N N N Sigilon Therapeutics Inc N/A 82657L206 297.00000000 NS USD 6685.47000000 0.001119369407 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -18.00000000 NC USD -8280.00000000 -0.00138634661 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Biogen, Inc. Biogen, Inc. 100.00000000 305.00000000 USD 2023-08-18 XXXX 3631.00000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -17.00000000 NC USD -5992.50000000 -0.00100334324 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Morphic Holding, Inc. Morphic Holding, Inc. 100.00000000 60.00000000 USD 2023-08-18 XXXX 1789.54000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -260.00000000 NC USD -65650.00000000 -0.01099198733 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merck & Co., Inc. Merck & Co., Inc. 100.00000000 114.00000000 USD 2023-07-14 XXXX -15843.96000000 N N N NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 000000000 -75.00000000 NC USD -5975.93000000 -0.00100056887 N/A DE US N 2 NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 Call Written Avantor, Inc. Avantor, Inc. 100.00000000 20.43000000 USD 2023-07-21 XXXX 3344.31000000 N N N CITIBANK NA E57ODZWZ7FF32TWEFA76 000000000 -1800.00000000 NC -7710.62000000 -0.00129101351 N/A DE US N 2 CITIBANK NA E57ODZWZ7FF32TWEFA76 Call Written Novo Nordisk AS Novo Nordisk AS 1.00000000 1117.35140000 DKK 2023-08-02 XXXX -70.40000000 N N N Incyte Corp 549300Z4WN6JVZ3T4680 45337C102 33358.00000000 NS USD 2076535.50000000 0.347680912745 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -18.00000000 NC USD -1449.00000000 -0.00024261065 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Moderna, Inc. Moderna, Inc. 100.00000000 135.00000000 USD 2023-07-21 XXXX 3128.34000000 N N N Reata Pharmaceuticals Inc 5299005F094GH9QDDD80 75615P103 6625.00000000 NS USD 675485.00000000 0.113098592028 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -74.00000000 NC USD -259.00000000 -0.00004336518 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bristol-Myers Squibb Co. Bristol-Myers Squibb Co. 100.00000000 68.00000000 USD 2023-07-14 XXXX 5194.50000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -72.00000000 NC USD -84600.00000000 -0.01416484583 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cigna Group Cigna Group 100.00000000 280.00000000 USD 2023-08-18 XXXX -23354.32000000 N N N Nautilus Biotechnology Inc N/A 63909J108 16560.00000000 NS USD 64087.20000000 0.010730322785 Long EC CORP US N 1 N N N BARCLAYS BANK PLC G5GSEF7VJP5I7OUK5573 000000000 -1200.00000000 NC -145.06000000 -0.00002428785 N/A DE US N 2 BARCLAYS BANK PLC G5GSEF7VJP5I7OUK5573 Call Written Roche Holding AG Roche Holding AG 1.00000000 290.77000000 CHF 2023-07-11 XXXX 4125.35000000 N N N AstraZeneca PLC PY6ZZQWO2IZFZC3IOL08 000000000 26401.00000000 NS 3784694.21000000 0.633683333319 Long EC CORP GB N 2 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -28.00000000 NC USD -7140.00000000 -0.00119547280 N/A DE NL N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merus NV Merus NV 100.00000000 30.00000000 USD 2023-08-18 XXXX -2633.91000000 N N N Intuitive Surgical Inc 54930052SRG011710797 46120E602 63429.00000000 NS USD 21688912.26000000 3.631443243336 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -48.00000000 NC USD -120000.00000000 -0.02009197990 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written West Pharmaceutical Services, Inc. West Pharmaceutical Services, Inc. 100.00000000 360.00000000 USD 2023-07-21 XXXX -65459.43000000 N N N JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 000000000 -63.00000000 NC USD -12669.11000000 -0.00212122919 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 Call Written Incyte Corp. Incyte Corp. 100.00000000 64.00000000 USD 2023-08-18 XXXX -839.64000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -63.00000000 NC USD -137970.00000000 -0.02310075389 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 320.00000000 USD 2023-07-14 XXXX -107646.42000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -77.00000000 NC USD -32725.00000000 -0.00547925035 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Quest Diagnostics, Inc. Quest Diagnostics, Inc. 100.00000000 140.00000000 USD 2023-08-18 XXXX -13374.55000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -96.00000000 NC USD -10752.00000000 -0.00180024139 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Johnson & Johnson Johnson & Johnson 100.00000000 170.00000000 USD 2023-08-04 XXXX 1915.90000000 N N N ICON PLC 6354008SRQGEMC4XFI67 000000000 8210.00000000 NS USD 2054142.00000000 0.343931498146 Long EC CORP IE N 1 N N N Amgen Inc 62QBXGPJ34PQ72Z12S66 031162100 61050.00000000 NS USD 13554321.00000000 2.269442875853 Long EC CORP US N 1 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -99.00000000 NC USD -57770.66000000 -0.00967272449 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Dexcom, Inc. Dexcom, Inc. 100.00000000 124.95000000 USD 2023-07-21 XXXX -21856.63000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -69.00000000 NC USD -93150.00000000 -0.01559639939 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Vertex Pharmaceuticals, Inc. Vertex Pharmaceuticals, Inc. 100.00000000 340.00000000 USD 2023-06-30 XXXX -49057.91000000 N N N Karuna Therapeutics Inc N/A 48576A100 2610.00000000 NS USD 565978.50000000 0.094763572052 Long EC CORP US N 1 N N N Immuneering Corp N/A 45254E107 14456.00000000 NS USD 146583.84000000 0.024542996392 Long EC CORP US N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -19.00000000 NC USD -4085.00000000 -0.00068396448 N/A DE KY N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written BeiGene Ltd. 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Omnicell, Inc. 100.00000000 75.00000000 USD 2023-08-18 XXXX 1135.18000000 N N N Pfizer Inc 765LHXWGK1KXCLTFYQ30 717081103 178976.00000000 NS USD 6564839.68000000 1.099171890860 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -2712.50000000 -0.00045416246 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cerevel Therapeutics Holdings, Inc. Cerevel Therapeutics Holdings, Inc. 100.00000000 35.00000000 USD 2023-08-18 XXXX 236.12000000 N N N Bio-Techne Corp 54930073RLKQ51TILZ35 09073M104 10625.00000000 NS USD 867318.75000000 0.145217924105 Long EC CORP US N 1 N N N GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 000000000 -12900.00000000 NC -11454.75000000 -0.00191790505 N/A DE US N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 Call Written Daiichi Sankyo Co. Ltd. Daiichi Sankyo Co. Ltd. 1.00000000 4670.09170000 JPY 2023-08-03 XXXX 1259.30000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -20.00000000 NC USD -19536.04000000 -0.00327098102 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Insulet Corp. 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Ultragenyx Pharmaceutical, Inc. 100.00000000 55.00000000 USD 2023-07-21 XXXX 719.88000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -20.00000000 NC USD -34100.00000000 -0.00570947095 N/A DE NL N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Argenx SE Argenx SE 100.00000000 450.00000000 USD 2023-08-18 XXXX 4000.11000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -1380.00000000 -0.00023105776 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Vaxcyte, Inc. Vaxcyte, Inc. 100.00000000 55.00000000 USD 2023-07-21 XXXX 1117.21000000 N N N UBS AG BFM8T61CT2L1QCEMIK50 000000000 -6700.00000000 NC -1530.51000000 -0.00025625813 N/A DE US N 2 UBS AG BFM8T61CT2L1QCEMIK50 Call Written AstraZeneca PLC AstraZeneca PLC 1.00000000 124.57120000 GBP 2023-07-18 XXXX 18159.86000000 N N N Legend Biotech Corp 254900EIUFZTW136H859 52490G102 31816.00000000 NS USD 2196258.48000000 0.367726510311 Long EC CORP KY N 1 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -150.00000000 NC USD -37040.10000000 -0.00620174120 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Medtronic PLC Medtronic PLC 100.00000000 89.00000000 USD 2023-09-08 XXXX 7925.17000000 N N N Money Market Series a series of SL Liquidity Series, LLC 549300I0RQO84VDWQP47 590204509 3419645.69000000 NS USD 3419987.65000000 0.572619359376 Long STIV US N N/A N N JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 000000000 -47.00000000 NC USD -44688.96000000 -0.00748241405 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 87.20000000 USD 2023-08-18 XXXX -28860.86000000 N N N AmerisourceBergen Corp AI8GXW8LG5WK7E9UD086 03073E105 59256.00000000 NS USD 11402632.08000000 1.909178788072 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -105.00000000 NC USD -107100.00000000 -0.01793209206 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Becton Dickinson & Co. Becton Dickinson & Co. 100.00000000 260.00000000 USD 2023-08-18 XXXX -57898.70000000 N N N Rapid Micro Biosystems Inc N/A 75340L104 20561.00000000 NS USD 20561.00000000 0.003442593322 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -2585.00000000 -0.00043281473 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alkermes PLC Alkermes PLC 100.00000000 32.00000000 USD 2023-08-18 XXXX 1325.92000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -1120.00000000 -0.00018752514 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Humana, Inc. Humana, Inc. 100.00000000 520.00000000 USD 2023-07-07 XXXX 17756.55000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -33.00000000 NC USD -6022.50000000 -0.00100836624 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Prothena Corp. PLC Prothena Corp. PLC 100.00000000 80.00000000 USD 2023-08-18 XXXX 6081.53000000 N N N Sanofi 549300E9PC51EN656011 000000000 24587.00000000 NS 2646932.07000000 0.443184216245 Long EC CORP FR N 2 N N N JEFFERIES LLC 58PU97L1C0WSRCWADL48 000000000 -48.00000000 NC USD -59708.06000000 -0.00999710951 N/A DE US N 2 JEFFERIES LLC 58PU97L1C0WSRCWADL48 Call Written Becton Dickinson & Co. Becton Dickinson & Co. 100.00000000 252.95000000 USD 2023-07-21 XXXX -30583.29000000 N N N Abcam PLC 213800B9N83DSNT33F79 000380204 57415.00000000 NS USD 1404945.05000000 0.235234397553 Long EC CORP GB N 1 N N N Prime Medicine Inc N/A 74168J101 22929.00000000 NS USD 335909.85000000 0.056242449622 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -70.00000000 NC USD -91700.00000000 -0.01535362130 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Vertex Pharmaceuticals, Inc. Vertex Pharmaceuticals, Inc. 100.00000000 340.00000000 USD 2023-07-14 XXXX -44379.87000000 N N N Ultragenyx Pharmaceutical Inc 529900EV44GVDN1DCX77 90400D108 6140.00000000 NS USD 283238.20000000 0.047423468513 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -12.00000000 NC USD -3150.00000000 -0.00052741447 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Omnicell, Inc. Omnicell, Inc. 100.00000000 75.00000000 USD 2023-07-21 XXXX -162.49000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -38.00000000 NC USD -1710.00000000 -0.00028631071 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Catalent, Inc. Catalent, Inc. 100.00000000 50.00000000 USD 2023-07-21 XXXX 334.43000000 N N N JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 000000000 -1300.00000000 NC -618.96000000 -0.00010363443 N/A DE US N 2 JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 Call Written Roche Holding AG Roche Holding AG 1.00000000 296.53200000 CHF 2023-07-25 XXXX 5656.56000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -20.00000000 NC USD -2850.00000000 -0.00047718452 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Regeneron Pharmaceuticals, Inc. Regeneron Pharmaceuticals, Inc. 100.00000000 785.00000000 USD 2023-07-21 XXXX 29603.16000000 N N N Design Therapeutics Inc N/A 25056L103 13967.00000000 NS USD 87992.10000000 0.014732795871 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -209.00000000 NC USD -56430.00000000 -0.00944825354 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merck & Co., Inc. Merck & Co., Inc. 100.00000000 116.00000000 USD 2023-08-04 XXXX -21999.90000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -14.00000000 NC USD -10430.00000000 -0.00174632791 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cigna Group Cigna Group 100.00000000 280.00000000 USD 2023-07-28 XXXX -2737.89000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -6955.00000000 -0.00116449766 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Apellis Pharmaceuticals, Inc. Apellis Pharmaceuticals, Inc. 100.00000000 95.00000000 USD 2023-07-21 XXXX 9365.32000000 N N N Arvinas Inc N/A 04335A105 14173.00000000 NS USD 351773.86000000 0.058898611039 Long EC CORP US N 1 N N N BeiGene Ltd 549300JFUK6FRD5MH739 07725L102 6630.00000000 NS USD 1182129.00000000 0.197927600902 Long EC CORP KY N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -10.00000000 NC USD -17250.00000000 -0.00288822211 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written West Pharmaceutical Services, Inc. West Pharmaceutical Services, Inc. 100.00000000 380.00000000 USD 2023-08-18 XXXX -7459.87000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -42.00000000 NC USD -25755.74000000 -0.00431236508 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 88.72000000 USD 2023-07-21 XXXX -12869.37000000 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -6400.00000000 NC USD -7755.71000000 -0.00129856307 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Genmab AS Genmab AS 1.00000000 39.39100000 USD 2023-08-23 XXXX 40.77000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -84.00000000 NC USD -4200.00000000 -0.00070321929 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rhythm Pharmaceuticals, Inc. Rhythm Pharmaceuticals, Inc. 100.00000000 20.00000000 USD 2023-08-18 XXXX 3256.69000000 N N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 20029.00000000 NS USD 1888734.70000000 0.316236830254 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -20.00000000 NC USD -1650.00000000 -0.00027626472 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bio-Techne Corp. Bio-Techne Corp. 100.00000000 85.00000000 USD 2023-07-21 XXXX 5706.62000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -910.00000000 -0.00015236418 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Hologic, Inc. Hologic, Inc. 100.00000000 85.00000000 USD 2023-07-21 XXXX 2724.01000000 N N N HCA Healthcare Inc 529900PH4ZGUH2MNEU89 40412C101 21285.00000000 NS USD 6459571.80000000 1.081546556450 Long EC CORP US N 1 N N N Masimo Corp 549300Q4A8JK0PIYCU29 574795100 12760.00000000 NS USD 2099658.00000000 0.351552386123 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -89.00000000 NC USD -38270.00000000 -0.00640766725 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Thermo Fisher Scientific, Inc. Thermo Fisher Scientific, Inc. 100.00000000 530.00000000 USD 2023-07-14 XXXX 39962.23000000 N N N Avantor Inc N/A 05352A100 78897.00000000 NS USD 1620544.38000000 0.271332875929 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -333.00000000 NC USD -39793.50000000 -0.00666275168 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Gilead Sciences, Inc. Gilead Sciences, Inc. 100.00000000 79.00000000 USD 2023-08-04 XXXX -5400.36000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -24.00000000 NC USD -7440.00000000 -0.00124570275 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Illumina, Inc. Illumina, Inc. 100.00000000 215.00000000 USD 2023-08-04 XXXX 7936.37000000 N N N McKesson Corp 549300WZWOM80UCFSF54 58155Q103 26075.00000000 NS USD 11142108.25000000 1.865558458439 Long EC CORP US N 1 N N N Humana Inc 529900YLDW34GJAO4J06 444859102 11855.00000000 NS USD 5300726.15000000 0.887517360549 Long EC CORP US N 1 N N N Bausch + Lomb Corp 549300NY6OZM39SO6475 071705107 75830.00000000 NS USD 1521908.10000000 0.254817891301 Long EC CORP CA N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -161.00000000 NC USD -66010.00000000 -0.01105226327 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Johnson & Johnson Johnson & Johnson 100.00000000 165.00000000 USD 2023-08-18 XXXX 646.83000000 N N N Danaher Corp S4BKK9OTCEWQ3YHPFM11 235851102 43329.00000000 NS USD 10398960.00000000 1.741130794252 Long EC CORP US N 1 N N N JEFFERIES LLC 58PU97L1C0WSRCWADL48 000000000 -80.00000000 NC USD -16213.92000000 -0.00271474795 N/A DE US N 2 JEFFERIES LLC 58PU97L1C0WSRCWADL48 Call Written Envista Holdings Corp. 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INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Genmab AS Genmab AS 1.00000000 2806.75000000 DKK 2023-07-13 XXXX 7727.70000000 N N N BlackRock Liquidity Funds 5493007YVNX55LTRQ706 09248U718 25514114.32000000 NS USD 25514114.32000000 4.271908934223 Long STIV RF US N 1 N N N CureVac NV 724500BUT8GAG9LMYN56 000000000 20488.00000000 NS USD 213484.96000000 0.035744462712 Long EC CORP NL N 1 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -900.00000000 NC USD -3587.20000000 -0.00060061625 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Glaukos Corp. Glaukos Corp. 1.00000000 69.82500000 USD 2023-07-31 XXXX -1143.97000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -87.00000000 NC USD -10657.50000000 -0.00178441896 N/A DE CH N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alcon, Inc. Alcon, Inc. 100.00000000 82.50000000 USD 2023-07-21 XXXX -2151.50000000 N N N Glaukos Corp 5299004JA1LHE21M6T14 377322102 4880.00000000 NS USD 347504.80000000 0.058183828808 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -16.00000000 NC USD -2200.00000000 -0.00036835296 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Masimo Corp. Masimo Corp. 100.00000000 175.00000000 USD 2023-07-21 XXXX 2923.86000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -53.00000000 NC USD -26765.00000000 -0.00448134868 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 90.00000000 USD 2023-07-21 XXXX -20799.94000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -52.00000000 NC USD -19760.00000000 -0.00330847935 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 195.00000000 USD 2023-08-04 XXXX -5761.53000000 N N N Decibel Therapeutics Inc N/A 24343R106 46884.00000000 NS USD 180503.40000000 0.030222255707 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -98.00000000 NC USD -47040.00000000 -0.00787605612 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Agilent Technologies, Inc. Agilent Technologies, Inc. 100.00000000 120.00000000 USD 2023-08-18 XXXX -15128.21000000 N N N Rocket Pharmaceuticals Inc 549300R7VV82YUIN4Y93 77313F106 17213.00000000 NS USD 342022.31000000 0.057265878151 Long EC CORP US N 1 N N N Mettler-Toledo International Inc 5493000BD5GJNUDIUG10 592688105 1055.00000000 NS USD 1383780.20000000 0.231690699713 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -118.00000000 NC USD -9381.00000000 -0.00157069052 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AbbVie, Inc. AbbVie, Inc. 100.00000000 145.00000000 USD 2023-08-18 XXXX 10878.77000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -14300.00000000 -0.00239429427 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Apellis Pharmaceuticals, Inc. Apellis Pharmaceuticals, Inc. 100.00000000 95.00000000 USD 2023-08-18 XXXX -2439.86000000 N N N Afferent Pharmaceuticals, Inc. N/A 000000000 190160.00000000 NS USD 152128.00000000 0.025471272653 Long EP CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -69.00000000 NC USD -43470.00000000 -0.00727831971 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written IQVIA Holdings, Inc. IQVIA Holdings, Inc. 100.00000000 230.00000000 USD 2023-08-18 XXXX -11353.32000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -260.00000000 NC USD -81900.00000000 -0.01371277628 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written GE HealthCare Technologies, Inc. GE HealthCare Technologies, Inc. 100.00000000 80.00000000 USD 2023-07-28 XXXX -24015.02000000 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -2200.00000000 NC USD -2188.47000000 -0.00036642246 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Vaxcyte, Inc. Vaxcyte, Inc. 1.00000000 54.78200000 USD 2023-07-31 XXXX 2230.67000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -162.00000000 NC USD -121500.00000000 -0.02034312964 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written UnitedHealth Group, Inc. UnitedHealth Group, Inc. 100.00000000 490.00000000 USD 2023-07-28 XXXX -16434.46000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -48.00000000 NC USD -104160.00000000 -0.01743983855 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 325.00000000 USD 2023-07-21 XXXX -53850.64000000 N N N Alkermes PLC N/A 000000000 32331.00000000 NS USD 1011960.30000000 0.169435716734 Long EC CORP IE N 1 N N N Elanco Animal Health Inc 549300SHPNDCE059M934 28414H103 51800.00000000 NS USD 521108.00000000 0.087250762185 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -25.00000000 NC USD -8687.50000000 -0.00145457562 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Reata Pharmaceuticals, Inc. Reata Pharmaceuticals, Inc. 100.00000000 101.00000000 USD 2023-07-07 XXXX 796.27000000 N N N Merck & Co Inc 4YV9Y5M8S0BRK1RP0397 58933Y105 243775.00000000 NS USD 28129197.25000000 4.709760548129 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -27.00000000 NC USD -9045.00000000 -0.00151443298 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 43.00000000 USD 2023-07-28 XXXX -5730.21000000 N N N Cooper Cos Inc/The QJKMVPIGLH7530PCUE20 216648402 12951.00000000 NS USD 4965801.93000000 0.831439938078 Long EC CORP US N 1 N N N Quest Diagnostics Inc 8MCWUBXQ0WE04KMXBX50 74834L100 40564.00000000 NS USD 5701675.84000000 0.954649636489 Long EC CORP US N 1 N N N STERIS PLC N/A 000000000 9590.00000000 NS USD 2157558.20000000 0.361246799911 Long EC CORP IE N 1 N N N Neurogene, Inc. Series B N/A 000000000 106790.00000000 NS USD 259499.70000000 0.043448856305 Long STIV CORP US Y 3 N N N West Pharmaceutical Services Inc 5493007NKRGM1RJQ1P16 955306105 15420.00000000 NS USD 5897687.40000000 0.987468472521 Long EC CORP US N 1 N N N PTC Therapeutics Inc 549300UJLWOIWFDGB318 69366J200 19555.00000000 NS USD 795301.85000000 0.133159906544 Long EC CORP US N 1 N N N Eli Lilly & Co FRDRIPF3EKNDJ2CQJL29 532457108 79376.00000000 NS USD 37225756.48000000 6.232826258267 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -48.00000000 NC USD -10680.00000000 -0.00178818621 N/A DE KY N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Legend Biotech Corp. Legend Biotech Corp. 100.00000000 75.00000000 USD 2023-08-18 XXXX 9795.72000000 N N N CARBON HEALTH TECHNOLOGIES INC N/A 000000000 89892.00000000 NS USD 1013981.76000000 0.169774176181 Long EC CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -120.00000000 NC USD -129300.00000000 -0.02164910834 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Eli Lilly & Co. Eli Lilly & Co. 100.00000000 470.00000000 USD 2023-07-28 XXXX -43538.42000000 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -5000.00000000 NC -3483.16000000 -0.00058319650 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Novo Nordisk AS Novo Nordisk AS 1.00000000 1149.69000000 DKK 2023-07-13 XXXX 15342.75000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -235.00000000 NC USD -102225.00000000 -0.01711585537 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Zoetis, Inc. Zoetis, Inc. 100.00000000 170.00000000 USD 2023-07-21 XXXX -45272.24000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -32.00000000 NC USD -24558.30000000 -0.00411187391 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Masimo Corp. Masimo Corp. 100.00000000 165.50000000 USD 2023-08-18 XXXX -7949.77000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -400.00000000 -0.00006697326 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rocket Pharmaceuticals, Inc. Rocket Pharmaceuticals, Inc. 100.00000000 22.50000000 USD 2023-07-21 XXXX 6088.61000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -340.00000000 NC USD -510.00000000 -0.00008539091 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Pfizer, Inc. Pfizer, Inc. 100.00000000 39.00000000 USD 2023-07-07 XXXX 19080.45000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -44.00000000 NC USD -880.00000000 -0.00014734118 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rhythm Pharmaceuticals, Inc. Rhythm Pharmaceuticals, Inc. 100.00000000 20.00000000 USD 2023-07-21 XXXX 1705.89000000 N N N Catalent Inc N/A 148806102 20045.00000000 NS USD 869151.20000000 0.145524737010 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -66.00000000 NC USD -495.00000000 -0.00008287941 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Biomea Fusion, Inc. Biomea Fusion, Inc. 100.00000000 40.00000000 USD 2023-07-21 XXXX 12553.34000000 N N N IDEXX Laboratories Inc OGMTXK0LUU1HKV2P0J84 45168D104 7185.00000000 NS USD 3608522.55000000 0.604186354554 Long EC CORP US N 1 N N N Hologic Inc 549300DYP6F5ZJL0LB74 436440101 10990.00000000 NS USD 889860.30000000 0.148992127185 Long EC CORP US N 1 N N N Baxter International Inc J5OIVXX3P24RJRW5CK77 071813109 111827.00000000 NS USD 5094838.12000000 0.853044875878 Long EC CORP US N 1 N N N Bristol-Myers Squibb Co HLYYNH7UQUORYSJQCN42 110122108 39106.00000000 NS USD 2500828.70000000 0.418721666466 Long EC CORP US N 1 N N N Insitro, Series C N/A 000000000 30616.00000000 NS USD 353002.48000000 0.059104322776 Long EC CORP US Y 3 N N N GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 000000000 -3400.00000000 NC -9467.08000000 -0.00158510317 N/A DE GB N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 Call Written AstraZeneca PLC AstraZeneca PLC 1.00000000 117.36200000 GBP 2023-08-16 XXXX 5246.34000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -30.00000000 NC USD -48600.00000000 -0.00813725185 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written IQVIA Holdings, Inc. IQVIA Holdings, Inc. 100.00000000 210.00000000 USD 2023-07-21 XXXX -34367.73000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -24.00000000 NC USD -11520.00000000 -0.00192883007 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written PTC Therapeutics, Inc. PTC Therapeutics, Inc. 100.00000000 65.00000000 USD 2023-07-21 XXXX -2240.72000000 N N N Gilead Sciences Inc 549300WTZWR07K8MNV44 375558103 184370.00000000 NS USD 14209395.90000000 2.379124140223 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -58.00000000 NC USD -60465.00000000 -0.01012384637 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Eli Lilly & Co. Eli Lilly & Co. 100.00000000 475.00000000 USD 2023-08-04 XXXX -3495.59000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 000000000 -35.00000000 NC USD -23425.85000000 -0.00392226422 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300E8QX0ZMRDC2M81 Call Written Exact Sciences Corp. Exact Sciences Corp. 100.00000000 91.00000000 USD 2023-08-18 XXXX 2816.61000000 N N N 2023-07-31 BlackRock Health Sciences Trust Chuck Pulsfort Chuck Pulsfort Assistant Treasurer