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Share-Based Payment Awards (Tables)

12 Months Ended

Dec. 31, 2021

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

The following table provides a reconciliation of stock option activity under the Company’s equity incentive plans and for inducement awards for the year ended December 31, 2021:

	Number of options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life		Aggregate Intrinsic Value
						(in years)		(in thousands)
Outstanding at January 1, 2021		1,338,880		$	20.86
Granted		1,313,727			12.59
Exercised		(8,112	)		12.26
Forfeited		(75,448	)		16.46
Expired		(51,367	)		31.04
Outstanding at December 31, 2021		2,517,680		$	16.49		8.06	$	775
Exercisable at December 31, 2021		916,461		$	22.41		6.25	$	103

Schedule of Key Assumptions Used

In determining the grant date fair value of option awards during the years ended December 31, 2021 and 2020, the Company applied the Black-Scholes option pricing model based on the following key assumptions:

	Year Ended December 31,	Year Ended December 31,
	2021	2020
Option life (in years)	4.75 - 6.08	5.50 - 6.10
Stock volatility	72% - 83%	64% - 70%
Risk-free interest rate	0.42% - 1.44%	0.32% - 1.76%
Expected dividends	0.0%	0.0%

Summary of Information about Stock Options

The following table summarizes information about employee, consultant and director stock options under the Company’s equity incentive plans for the years ended December 31, 2021 and 2020 (in thousands except per share amounts):

	Year Ended December 31,		Year Ended December 31,
	2021		2020
Weighted-average grant date fair value per share	$	8.20	$	7.07
Total cash received from exercise of stock options		100		—
Total intrinsic value of stock options exercised		10		—

Summary of Restricted Stock Unit Activity

The following table provides a reconciliation of RSU activity under the 2016 Plan for the year ended December 31, 2021:

	Number of Restricted Stock Units			Weighted Average Grant Date Fair Value
Nonvested at January 1, 2021		149,004		$	13.85
Granted		242,399			12.96
Vested		(89,795	)		13.76
Forfeited		(10,033	)		12.15
Nonvested at December 31, 2021		291,575		$	13.19

Compensation Expense from Stock-Based Payment Awards

The Company’s statements of comprehensive loss included total compensation expense from stock-based payment awards as follows (in thousands):

	Year Ended December 31,		Year Ended December 31,
	2021		2020
Compensation expense included in:
Research and development	$	2,294	$	1,411
Sales and marketing		1,187		907
General and administrative		3,966		3,229
	$	7,447	$	5,547