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License and Collaboration Agreements - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 01, 2021
Jan. 01, 2020
USD ($)
Jan. 01, 2019
USD ($)
Jul. 10, 2017
USD ($)
Oct. 25, 2016
USD ($)
Dec. 31, 2017
USD ($)
Mar. 31, 2013
USD ($)
Jun. 30, 2011
USD ($)
Dec. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Dec. 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
Dec. 31, 2017
USD ($)
Country
Dec. 31, 2016
USD ($)
Jun. 30, 2017
USD ($)
Collaborative Agreements And Contracts [Line Items]                              
Collaborative research and development revenue                 $ 461,000   $ 5,702,000   $ 601,000 $ 5,736,000  
Royalty income                 472,000   269,000   717,000 $ 512,000  
Accounts receivable           $ 288,000     288,000       $ 288,000   $ 251,000
ILUVIEN [Member] | Europe [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Number of countries in which lead product received regulatory approval | Country                         17    
Prior Alimera Agreement [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Percentage of company's share of net profits                           20.00%  
Pre-profitability net losses percentage                           20.00%  
Maximum percentage offset of current period net profits against previously incurred and unapplied pre-profitability quarterly net losses                           4.00%  
Percentage of net profit share after offset of previously incurred and unapplied pre-profitability net losses                           16.00%  
Percentage of royalties received from sublicense                           20.00%  
Percentage of non-royalty consideration received from sublicense                           33.00%  
Amount received, profit share from sale of licensed products                   $ 50,000          
Amended Alimera Agreement [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Royalty percentage earned from sales of product                         2.00%    
Contingently recoverable accumulated commercialization losses       $ 25,000,000                      
Partial cancellation of contingently recoverable accumulated commercialization losses in lieu of upfront license fee       $ 10,000,000                      
Proceeds received from earned sales-based royalties                 196,000       $ 196,000    
Amended Alimera Agreement [Member] | Scenario, Forecast [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Calendar year net sales threshold for increase in royalty rate     $ 75,000,000                        
Royalty percentage offset for amounts earned above 2% to be applied against balance of accumulated commercialization losses 20.00%   50.00%                        
Additional cancellation of contingently recoverable commercialization losses   $ 5,000,000                          
Amended Alimera Agreement [Member] | Scenario, Forecast [Member] | Minimum [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Royalty percentage earned from sales of product     6.00%                        
Amended Alimera Agreement [Member] | Scenario, Forecast [Member] | Maximum [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Royalty percentage earned from sales of product     8.00%                        
Pfizer Collaboration Agreement [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Upfront cash payment received under collaboration agreement               $ 2,300,000              
Estimated selling price of the deliverables for revenue recognition               $ 6,700,000              
Collaborative research and development revenue                     5,600,000 $ 0      
Option period to acquire license         60 days                    
License option upfront payment upon exercise         $ 10,000,000                    
Bausch and Lomb [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Royalty income                 276,000   269,000   521,000 $ 512,000  
Accounts receivable           277,000     277,000       $ 277,000   246,000
OncoSil Medical UK Limited [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Percentage of non-royalty consideration received from sublicense                         20.00%    
Royalty percentage earned from sales of product                         8.00%    
Collaborative research and development revenue                 100,000   100,000   $ 100,000 100,000  
License agreement commencement date                         2012-12    
Receipt of upfront license fee             $ 100,000                
Payment of annual license maintenance fee           100,000                  
Deferred revenue           0     0       $ 0    
Feasibility Study Agreement [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Upfront cash payment received under collaboration agreement                 850,000            
Collaborative research and development revenue                 355,000   3,000   405,000 11,000  
Deferred revenue           $ 505,000     505,000       505,000   $ 50,000
Prior Alimera Agreement and/or Amended Alimera Agreement [Member]                              
Collaborative Agreements And Contracts [Line Items]                              
Total revenues earned from Alimera                 $ 200,000   $ 14,000   $ 290,000 $ 34,000