-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 B3wwgBU3QaxX969fTo4Ls1EL1UPIp8AYjVGqKzBdxPo+NSF7mDMb5GtecuHxBArj
 HXAyldldLc0AbYOWffwU/A==

<SEC-DOCUMENT>0001313281-05-000004.txt : 20050825
<SEC-HEADER>0001313281-05-000004.hdr.sgml : 20050825
<ACCEPTANCE-DATETIME>20050825201736
ACCESSION NUMBER:		0001313281-05-000004
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050825
FILED AS OF DATE:		20050825
DATE AS OF CHANGE:		20050825

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Macquarie Global Infrastructure Total Return Fund Inc.
		CENTRAL INDEX KEY:			0001326390
		IRS NUMBER:				342045907

	BUSINESS ADDRESS:	
		STREET 1:		C/O MACQUARIE INFRASTRUCTURE FUND ADVISE
		STREET 2:		600 FIFTH AVENUE, LEVEL 21
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10020
		BUSINESS PHONE:		212-548-6597

	MAIL ADDRESS:	
		STREET 1:		C/O MACQUARIE INFRASTRUCTURE FUND ADVISE
		STREET 2:		600 FIFTH AVENUE, LEVEL 21
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10020

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Macquarie Infrastructure Fund Adviser, LLC
		CENTRAL INDEX KEY:			0001313281

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21765
		FILM NUMBER:		051050019

	BUSINESS ADDRESS:	
		STREET 1:		600 FIFTH AVENUE, LEVEL 20
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10020
		BUSINESS PHONE:		212-548-6597

	MAIL ADDRESS:	
		STREET 1:		600 FIFTH AVENUE, LEVEL 20
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10020
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2005-08-25</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001326390</issuerCik>
        <issuerName>Macquarie Global Infrastructure Total Return Fund Inc.</issuerName>
        <issuerTradingSymbol>MGU</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001313281</rptOwnerCik>
            <rptOwnerName>Macquarie Infrastructure Fund Adviser, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>125 WEST 55TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10020</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Adviser</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4189</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>Rose E. Barry</signatureName>
        <signatureDate>2005-08-25</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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