0001306923-24-000008.txt : 20240515 0001306923-24-000008.hdr.sgml : 20240515 20240515161048 ACCESSION NUMBER: 0001306923-24-000008 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240331 FILED AS OF DATE: 20240515 DATE AS OF CHANGE: 20240515 EFFECTIVENESS DATE: 20240515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Palo Alto Investors LP CENTRAL INDEX KEY: 0001306923 ORGANIZATION NAME: IRS NUMBER: 770558164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11013 FILM NUMBER: 24950728 BUSINESS ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 BUSINESS PHONE: 650-325-0772 MAIL ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 FORMER COMPANY: FORMER CONFORMED NAME: Palo Alto Investors, LLC DATE OF NAME CHANGE: 20041025 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001306923 XXXXXXXX 03-31-2024 03-31-2024 Palo Alto Investors LP

470 UNIVERSITY AVE PALO ALTO CA 94301

13F HOLDINGS REPORT 028-11013 000109171 801-58166 N Angela Nguyen-Dinh 650-325-0772 Angela Nguyen-Dinh Palo Alto CA 05-15-2024 0 38 886726077 false INFORMATION TABLE 2 13F.xml ACADIA PHARMACEUTICALS INC COM 004225108 44652296 2414943 SH SOLE 2414943 0 0 ACELYRIN INC COM 00445A100 11577465 1715180 SH SOLE 1715180 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 706592 569832 SH SOLE 569832 0 0 ALDEYRA THERAPEUTICS INC COM 01438T106 737271 225465 SH SOLE 225465 0 0 ALIGN TECHNOLOGY INC COM 016255101 16102512 49105 SH SOLE 49105 0 0 ALKERMES PLC SHS G01767105 13415675 495592 SH SOLE 495592 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 27314379 182766 SH SOLE 182766 0 0 AMICUS THERAPEUTICS INC COM 03152W109 110073522 9344102 SH SOLE 9344102 0 0 ANAPTYSBIO INC COM 032724106 18013883 799906 SH SOLE 799906 0 0 BIOGEN INC COM 09062X103 62523644 289958 SH SOLE 289958 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 99093257 1134569 SH SOLE 1134569 0 0 BLUEBIRD BIO INC COM 09609G100 5837019 4560171 SH SOLE 4560171 0 0 CYTOKINETICS INC COM NEW 23282W605 7832479 111717 SH SOLE 111717 0 0 EHEALTH INC COM 28238P109 16375556 2715681 SH SOLE 2715681 0 0 ELEVATION ONCOLOGY INC COM 28623U101 6908397 1346666 SH SOLE 1346666 0 0 GOSSAMER BIO INC COM 38341P102 7542295 6391775 SH SOLE 6391775 0 0 HUMANA INC COM 444859102 1381679 3985 SH SOLE 3985 0 0 INSMED INC COM PAR $.01 457669307 120006001 4423369 SH SOLE 4423369 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 31311859 2112811 SH SOLE 2112811 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 7704311 5102193 SH SOLE 5102193 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 1625264 64700 SH SOLE 64700 0 0 NEVRO CORP COM 64157F103 10835357 750371 SH SOLE 750371 0 0 NOVOCURE LTD ORD SHS G6674U108 8782622 561908 SH SOLE 561908 0 0 NUVATION BIO INC COM 67080N101 2812453 772652 SH SOLE 772652 0 0 PROTHENA CORP PLC SHS G72800108 41203607 1663448 SH SOLE 1663448 0 0 RELMADA THERAPEUTICS INC COM 75955J402 3405660 732400 SH SOLE 732400 0 0 REVANCE THERAPEUTICS INC COM 761330109 25820180 5248004 SH SOLE 5248004 0 0 SAGE THERAPEUTICS INC COM 78667J108 18848242 1005776 SH SOLE 1005776 0 0 SAREPTA THERAPEUTICS INC COM 803607100 26055767 201265 SH SOLE 201265 0 0 STAAR SURGICAL CO COM PAR $0.01 852312305 52810705 1379590 SH SOLE 1379590 0 0 STOKE THERAPEUTICS INC COM 86150R107 1699124 125861 SH SOLE 125861 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 9643593 405193 SH SOLE 405193 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 2328339 811268 SH SOLE 811268 0 0 TRAVERE THERAPEUTICS INC COM 89422G107 853643 110719 SH SOLE 110719 0 0 UNITED THERAPEUTICS CORP COM 91307C102 61509597 267759 SH SOLE 267759 0 0 UROGEN PHARMA LTD COM M96088105 367500 24500 SH SOLE 24500 0 0 VERVE THERAPEUTICS INC COM 92539P101 7646850 575817 SH SOLE 575817 0 0 VYNE THERAPEUTICS INC COM 92941V308 1367482 445434 SH SOLE 445434 0 0