SCHEDULE 14A
(RULE 14a-101)
INFORMATION REQUIRED IN PROXY STATEMENT

SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a)
of the Securities Exchange Act of 1934

Filed by the Registrant x

Filed by a Party other than the Registrant ¨

Check the appropriate box:

¨ Preliminary Proxy Statement

¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

¨ Definitive Proxy Statement

ý Definitive Additional Materials

¨ Soliciting Material Under Rule 14a-12

LIFEPOINT HOSPITALS, INC.

(Name of Registrant as Specified in its Charter)

Payment of Filing Fee (Check the appropriate box):

x No fee required.

¨ Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

(1)	Title of each class of securities to which transaction applies: N/A
(2)	Aggregate number of securities to which transaction applies: N/A
(3)	Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the filing fee is calculated and state how it was determined): N/A
(4)	Proposed maximum aggregate value of transaction: N/A
(5)	Total fee paid: N/A

¨ Fee paid previously with preliminary materials.

¨ Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.

(1)	Amount Previously Paid: N/A
(2)	Form, Schedule or Registration Statement No.: N/A
(3)	Filing Party: N/A
(4)	Date Filed: N/A

On April 25, 2006, LifePoint Hospitals issued the following press release:

Contact:	Michael J. Culotta
	Chief Financial Officer
	(615) 372-8512

DELAWARE CHANCERY COURT RULES IN FAVOR OF LIFEPOINT HOSPITALS

Annual Meeting of Stockholders to be Held on May 8, 2006

Brentwood, Tennessee (April 25, 2006) — LifePoint Hospitals, Inc. (the “Company”) (NASDAQ: LPNT) announced today that the Delaware Chancery Court denied Accipiter Life Sciences Fund, L.P.’s motion for a preliminary injunction in connection with the Company’s 2006 Annual Meeting of Stockholders. Consequently, the Company intends to hold its 2006 Annual Meeting of Stockholders on May 8, 2006, as previously scheduled.

******

Important Legal Information

In connection with the Company’s 2006 Annual Meeting of Stockholders (the “Annual Meeting”), the Company filed a definitive proxy statement with the Securities and Exchange Commission (the “SEC”) on April 7, 2006 and may file additional proxy materials. Stockholders and other interested parties are urged to read the definitive proxy statement, carefully and in its entirety, because it contains important information about the Company and the Annual Meeting. This definitive proxy statement has been sent to the stockholders of the Company. You may obtain free copies of the definitive proxy statement, and other documents filed with, or furnished to, the SEC by the Company at the SEC’s website at www.sec.gov. The definitive proxy statement, and other documents may also be obtained for free from the Company by writing to Shareholder Services, LifePoint Hospitals, Inc., 103 Powell Court, Suite 200, Brentwood, Tennessee 37027.

All references to “LifePoint Hospitals” or the “Company” as used throughout this release refer to LifePoint Hospitals, Inc. and its affiliates.

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