Revenue Recognition - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Revenue Recognition Milestone Method [Line Items]
Revenue recognition cash discount percentage	2.30%
Provision for chargebacks and other deductions included as reduction of accounts receivable total	$ 29,470,000	$ 22,869,000
Deferred revenue	2,823,000	2,798,000
Revenue recognized commercial milestones	2,500,000	25,000,000.0
Commercial Platform
Revenue Recognition Milestone Method [Line Items]
Provision for chargebacks and other deductions included as reduction of accounts receivable total	29,470,000	22,869,000
Chargebacks and other revenue deductions expense	179,900	129,000,000.0
Oncology Innovation Platform | Out-license Revenue
Revenue Recognition Milestone Method [Line Items]
Deferred revenue	2,800	2,700,000
Licensed IP
Revenue Recognition Milestone Method [Line Items]
Revenue recognized	0	0
Deferred revenue	2,700,000	2,700,000
TCR-T technology
Revenue Recognition Milestone Method [Line Items]
Upfront fees received		2,000,000.0
Klisyri
Revenue Recognition Milestone Method [Line Items]
Revenue recognized		700,000
Royalty revenue
Revenue Recognition Milestone Method [Line Items]
Revenue recognized royalties	2,300,000	1,000,000.0
Transferred at a Point in Time | Licensed IP
Revenue Recognition Milestone Method [Line Items]
Revenue recognized	$ 9,200	$ 500