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Accrued expenses and other current liabilities (Tables)
3 Months Ended
Mar. 31, 2019
Payables And Accruals [Abstract]  
Summary of Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities consist of the following (in thousands):

 

 

 

As of

 

 

As of

 

 

 

March 31, 2019

 

 

December 31, 2018

 

Employee compensation

 

$

16,404

 

 

$

28,567

 

Accrued manufacturing costs

 

 

12,125

 

 

 

21,618

 

Accrued clinical and contract research organization

   costs

 

 

14,724

 

 

 

11,891

 

Accrued license and milestone fees

 

 

323

 

 

 

7,739

 

Accrued professional fees

 

 

1,906

 

 

 

1,830

 

Financing lease obligation, current portion

 

 

 

 

 

1,424

 

Other

 

 

30,670

 

 

 

26,324

 

Total accrued expenses and other current

   liabilities

 

$

76,152

 

 

$

99,393