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Condensed Consolidated Balance Sheets (Unaudited) - USD ($)
$ in Thousands
Mar. 31, 2019
Dec. 31, 2018
Current Assets:    
Cash and cash equivalents $ 221,738 $ 402,579
Marketable securities 1,100,079 982,725
Prepaid expenses 23,766 19,762
Receivables and other current assets 19,449 13,931
Total current assets 1,365,032 1,418,997
Marketable securities 408,949 506,123
Property, plant and equipment, net 114,030 246,622
Intangible assets, net 12,228 13,169
Goodwill 13,128 13,128
Operating lease right-of-use assets 184,618  
Restricted cash and other non-current assets 40,630 44,805
Total assets 2,138,615 2,242,844
Current Liabilities:    
Accounts payable 30,241 17,831
Accrued expenses and other current liabilities 76,152 99,393
Operating lease liability, current portion 17,566  
Deferred revenue, current portion 11,490 18,602
Collaboration research advancement, current portion 11,242 10,605
Total current liabilities 146,691 146,431
Deferred revenue, net of current portion 14,777 16,338
Collaboration research advancement, net of current portion 30,746 33,349
Contingent consideration 5,526 5,230
Operating lease liability, net of current portion 168,200  
Financing lease obligation, net of current portion   153,319
Other non-current liabilities 576 3,107
Total liabilities 366,516 357,774
Commitments and contingencies (Note 8)
Stockholders’ Equity:    
Preferred stock, $0.01 par value, 5,000 shares authorized; 0 shares issued and outstanding at March 31, 2019 and December 31, 2018
Common stock, $0.01 par value, 125,000 shares authorized; 55,069 and 54,738 shares issued and outstanding at March 31, 2019 and December 31, 2018, respectively 551 547
Additional paid-in capital 3,430,030 3,386,958
Accumulated other comprehensive loss (1,792) (3,627)
Accumulated deficit (1,656,690) (1,498,808)
Total stockholders’ equity 1,772,099 1,885,070
Total liabilities and stockholders’ equity $ 2,138,615 $ 2,242,844