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Stock-based compensation - Summary of Stock Option Activity Under Plan (Details)
3 Months Ended
Mar. 31, 2024
$ / shares
shares
Shares (in thousands)  
Outstanding at beginning of period (in shares) | shares 4,227,000
Granted (in shares) | shares 2,572,000
Exercised (in shares) | shares 0
Canceled, forfeited, or expired (in shares) | shares (229,000)
Outstanding at end of period (in shares) | shares 6,570,000
Exercisable at end of period (in shares) | shares 1,871,000
Vested and expected to vest at end of period (in shares) | shares 6,570,000
Weighted- average exercise price per share  
Outstanding at beginning of period (in dollars per share) | $ / shares $ 14.16
Granted (in dollars per share) | $ / shares 1.56
Exercised (in dollars per share) | $ / shares 0
Canceled, forfeited, or expired (in dollars per share) | $ / shares 16.55
Outstanding at end of period (in dollars per share) | $ / shares 9.16
Exercisable at end of period (in dollars per share) | $ / shares 22.75
Vested and expected to vest at end of period (in dollars per share) | $ / shares $ 9.16