Stock-based compensation - Summary of Stock Option Activity Under Plan (Detail) $ / shares in Units, shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($) $ / shares shares
Shares (in thousands)
Outstanding at beginning of period (in shares) | shares	2,668
Granted (in shares) | shares	2,077
Exercised (in shares) | shares	(3)
Canceled or forfeited (in shares) | shares	(515)
Outstanding at end of period (in shares) | shares	4,227
Exercisable at end of period (in shares) | shares	1,469
Vested and expected to vest at end of period (in shares) | shares	4,227
Weighted- average exercise price per share
Outstanding at beginning of period (in dollars per share) | $ / shares	$ 24.38
Granted (in dollars per share) | $ / shares	4.89
Exercised (in dollars per share) | $ / shares	2.74
Canceled or forfeited (in dollars per share) | $ / shares	29.55
Outstanding at end of period (in dollars per share) | $ / shares	14.16
Exercisable at end of period (in dollars per share) | $ / shares	28.80
Vested and expected to vest at end of period (in dollars per share) | $ / shares	$ 14.16
Weighted- average contractual life (in years)
Outstanding at end of period	8 years 21 days
Exercisable at end of period	6 years 6 months 14 days
Vested and expected to vest at end of period	8 years 21 days
Aggregate intrinsic value (in thousands)
Outstanding at end of period | $	$ 0
Exercisable at end of period | $	0
Vested and expected to vest at end of period | $	$ 0