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Property, plant and equipment, net - Summary of Property, Plant and Equipment Net (Detail) - USD ($)
$ in Thousands
Sep. 30, 2022
Dec. 31, 2021
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment $ 35,107 $ 30,112
Less accumulated depreciation and amortization (23,572) (20,406)
Property, plant and equipment, net 11,535 9,706
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 28,866 29,061
Computer equipment and software    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 1,752 421
Office equipment    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 4,351 117
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 0 12
Construction-in-progress    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment $ 138 $ 501