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Property, plant and equipment, net (Tables)
 9 Months Ended
Sep. 30, 2020
Property, Plant and Equipment [Abstract]  
Summary of Property, Plant and Equipment Net
Property, plant and equipment, net, consists of the following (in thousands):
As of September 30, 2020As of December 31, 2019
Land
$1,210 $1,210 
Building
15,745 15,664 
Computer equipment and software
6,845 6,947 
Office equipment
7,626 7,599 
Laboratory equipment
52,366 44,560 
Leasehold improvements
34,104 33,788 
Construction-in-progress
86,858 77,981 
Total property, plant and equipment
204,754 187,749 
Less accumulated depreciation and amortization
(47,073)(36,573)
Property, plant and equipment, net
$157,681 $151,176