Exhibit 107

Calculation of Filing Fee Tables

424(b)(5)

(Form Type)

bluebird bio, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security Type	Security Class Title	Fee  Calculation  or Carry Forward Rule	Amount Registered	Proposed  Maximum  Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of Registration Fee	Carry  Forward  Form Type	Carry  Forward  File Number	Carry  Forward  Initial effective date	Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Fees to Be Paid	Equity	Common Stock, $0.01 par value per share	Rule 457(r)	23,000,000(1)	$6.00	$138,000,000.00	0.00011020	$15,207.60(2)	—	—	—	—
Fees Previously Paid	—	—	—	—	—	—	—	—	—	—	—	—
Carry Forward Securities
Carry Forward Securities	—		—	—	—	—	—	—	—	—	—	—
	Total Offering Amounts					$138,000,000.00		$15,207.60
	Total Fees Previously Paid							—
	Total Fee Offsets							—
	Net Fee Due							$15,207.60

(1) The amount registered includes shares of Common Stock that may be purchased by the underwriters pursuant to their option to purchase additional shares of Common Stock.

(2) The registration fee relates to the Registration Statement on Form S-3ASR (File No. 333-236489) filed by the Registrant on February 18, 2020.