Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock - $ / shares		3 Months Ended
		Mar. 31, 2023	Dec. 31, 2022
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Shares of Common Stock Subject to Warrants	[1]	6,459,317	1,291,213
Warrants Exercise Price One [Member] | February 2015 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 66,000
Expiration		February 2025
Shares of Common Stock Subject to Warrants	[1]	23	23
Warrants Exercise Price Two [Member] | February 2018 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 1,625
Expiration		February 2023
Shares of Common Stock Subject to Warrants	[1]		462
Warrants Exercise Price Three [Member] | February 2018 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 1,300
Expiration		February 2023
Shares of Common Stock Subject to Warrants	[1]		3,848
Warrants Exercise Price Four [Member] | October 2019 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 40
Expiration		October 2024
Shares of Common Stock Subject to Warrants	[1]	17,700	17,700
Warrants Exercise Price Five [Member] | October 2019 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 52
Expiration		October 2024
Shares of Common Stock Subject to Warrants	[1]	11,750	11,750
Warrants Exercise Price Six [Member] | November 2020 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 50.44
Expiration		May 2026
Shares of Common Stock Subject to Warrants	[1]	12,107	12,107
Warrants Exercise Price Seven [Member] | February 2021 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 78
Expiration		August 2026
Shares of Common Stock Subject to Warrants	[1]	20,834	20,834
Warrants Exercise Price Eight [Member] | October 2022 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 7.54
Expiration		April 2028
Shares of Common Stock Subject to Warrants	[1]	1,224,489	1,224,489
Warrants Exercise Price Nine [Member] | January 2023 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 2.65
Expiration		July 2024
Shares of Common Stock Subject to Warrants		2,586,207
Warrants Exercise Price Ten [Member] | January 2023 [Member]
Stockholders' Equity (Details) - Schedule of outstanding warrants to purchase shares of common stock [Line Items]
Exercise Price (in Dollars per share)		$ 2.65
Expiration		January 2028
Shares of Common Stock Subject to Warrants		2,586,207

[1] Warrants to purchase fractional shares of common stock resulting from the reverse stock splits on August 22, 2019 and January 5, 2023 were rounded up to the next whole share of common stock on a holder by holder basis.