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Stockholders' Equity (Details 2) (USD $)
1 Months Ended 12 Months Ended
Jan. 31, 2011
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Feb. 28, 2010
Stock-Based Compensation Plans          
Vesting period   4 years      
Vesting period expiration   10 years      
Number of Shares          
Balance at the beginning of the period (in shares)   1,820,784kbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIssuedAndOutstandingNumber      
Options granted (in shares)   1,298,500us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross      
Options forfeited (in shares)   (258,969)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod      
Options expired (in shares)   (126,123)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod      
Options exercised (in shares)   (56,418)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised      
Balance at the end of the period (in shares)   2,677,774kbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIssuedAndOutstandingNumber 1,820,784kbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIssuedAndOutstandingNumber    
Weighted-Average Exercise Price (Per Share)          
Balance at the beginning of the period (in dollars per share)   $ 4.46us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice      
Options granted (in dollars per share)   $ 4.24us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice      
Options forfeited (in dollars per share)   $ 5.81us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice      
Options expired (in dollars per share)   $ 5.49us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice      
Options exercised (in dollars per share)   $ 1.17us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice      
Balance at the ending of the period (in dollars per share)   $ 4.24us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 4.46us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice    
Warrants to purchase common stock   88,545us-gaap_ClassOfWarrantOrRightOutstanding      
Total common stock reserved for future issuance   3,985,244us-gaap_CommonStockCapitalSharesReservedForFutureIssuance      
Number of shares authorized to be issued under the plan 141,795us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized       153,026us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
Equity Incentive Plan period   10 years      
Awards, common stock vested 56,998us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod        
Stock-based compensation expense   $ 2,013,000us-gaap_AllocatedShareBasedCompensationExpense $ 1,440,000us-gaap_AllocatedShareBasedCompensationExpense $ 821,000us-gaap_AllocatedShareBasedCompensationExpense  
Total fair value of options vested   3,200,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1 1,600,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1 97,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1  
Total intrinsic value of stock options exercised   187,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue 787,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue 607,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue  
Weighted-average fair value of options granted during the period   $ 2.73us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 3.03us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 6.98us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue  
Two Thousand One Stock Option Plan [Member]          
Weighted-Average Exercise Price (Per Share)          
Warrants to purchase common stock   555,774us-gaap_ClassOfWarrantOrRightOutstanding
/ us-gaap_PlanNameAxis
= kbio_TwoThousandOneStockOptionPlanMember
     
Two Thousand One Stock Option Plan [Member] | Maximum [Member]          
Weighted-Average Exercise Price (Per Share)          
Number of shares authorized to be issued under the plan   3,408,247us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= kbio_TwoThousandOneStockOptionPlanMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
     
Fair market value percentage of ordinary shares   85.00%kbio_FairMarketValuePercentage
/ us-gaap_PlanNameAxis
= kbio_TwoThousandOneStockOptionPlanMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
     
Equity Incentive Plan Twenty Twelve [Member]          
Stock-Based Compensation Plans          
Vesting period   4 years      
Vesting period expiration   10 years      
Weighted-Average Exercise Price (Per Share)          
Warrants to purchase common stock   2,122,000us-gaap_ClassOfWarrantOrRightOutstanding
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Shares available for future grant   1,218,925us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Number of shares authorized to be issued under the plan, before 2001 Plan additions   1,123,131kbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorizedBaseNumber
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Carryover of shares from 2001 Plan   1,066,975kbio_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorizedCarryoverFromPreviousStockPlan
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Percentage of increase in the number of shares reserved for issuance   5.00%kbio_OutstandingCommonStockPercentage
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Increase in the number of shares reserved for issuance   842,348kbio_IncreaseInCommonStockReservedForIssuance
/ us-gaap_PlanNameAxis
= kbio_EquityIncentivePlanTwentyTwelveMember
     
Fiscal year over which number of shares reserved for issuance will increase, starting year   2013      
Fiscal year over which number of shares reserved for issuance will increase, ending year   2022      
Employee Stock Purchase Plan Twenty Twelve [Member]          
Stock-Based Compensation Plans          
Look-back period for payroll deductions to acquire ownership interest   6 months      
Weighted-Average Exercise Price (Per Share)          
Number of shares authorized to be issued under the plan   168,469us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= kbio_EmployeeStockPurchasePlanTwentyTwelveMember
     
Fair market value percentage of ordinary shares   85.00%kbio_FairMarketValuePercentage
/ us-gaap_PlanNameAxis
= kbio_EmployeeStockPurchasePlanTwentyTwelveMember
     
Stock Awards [Member]          
Weighted-Average Exercise Price (Per Share)          
Stock-based compensation expense       $ 401,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_PlanNameAxis
= kbio_StockAwardsMember