The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADR 90138A103 11,102 525,189 SH   DFND   525,189 0 0
ACCELERON PHARMA INC COM 00434H108 31,221 640,300 SH   DFND   640,300 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 8,027 665,566 SH   DFND   665,566 0 0
AGENUS INC COM NEW 00847G705 12,169 2,680,321 SH   DFND   2,680,321 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 3,641 263,921 SH   DFND   263,921 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 2,853 3,000,000 PRN   DFND   3,000,000 0 0
ARROWHEAD RESH CORP COM NEW 042797209 12,001 1,951,382 SH   DFND   1,951,382 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 3,617 535,000 SH   DFND   535,000 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 6,912 340,986 SH   DFND   340,986 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 14,016 1,358,097 SH   DFND   1,358,097 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 2,780 26,540 SH   DFND   26,540 0 0
BLUEBIRD BIO INC COM 09609G100 3,789 59,002 SH   DFND   59,002 0 0
BONA FILM GROUP LTD SPONSORED ADS 09777B107 8,457 639,211 SH   DFND   639,211 0 0
BRF SA SPONSORED ADR 10552T107 8,390 607,112 SH   DFND   607,112 0 0
CBRE GROUP INC CL A 12504L109 22,823 660,000 SH   DFND   660,000 0 0
CHINA ZENIX AUTO INTL LTD ADS 16951E104 3,639 6,074,805 SH   DFND   6,074,805 0 0
CITIZENS FINL GROUP INC COM 174610105 20,297 775,000 SH   DFND   775,000 0 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 22,114 25,500,000 PRN   DFND   25,500,000 0 0
CTRIP COM INTL LTD NOTE 1.250%10/1 22943FAD2 46,457 35,000,000 PRN   DFND   35,000,000 0 0
CYTRX CORP COM PAR $.001 232828509 14,480 5,850,399 SH   DFND   5,850,399 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 3,726 460,522 SH   DFND   460,522 0 0
DHT HOLDINGS INC DEBT 4.500%10/0 23335SAB2 20,220 17,000,000 PRN   DFND   17,000,000 0 0
E HOUSE CHINA HLDGS LTD ADR 26852W103 5,097 810,400 SH   DFND   810,400 0 0
EPIZYME INC COM 29428V104 9,537 595,314 SH   DFND   595,314 0 0
EQUITY COMWLTH COM SH BEN INT 294628102 35,081 1,265,079 SH   DFND   1,265,079 0 0
FIBROCELL SCIENCE INC COM NEW 315721209 8,344 1,913,662 SH   DFND   1,913,662 0 0
FIRST SOLAR INC COM 336433107 6,599 100,000 SH Put DFND   100,000 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 10,244 246,848 SH   DFND   246,848 0 0
GOLAR LNG LTD BERMUDA SHS G9456A100 4,741 300,283 SH   DFND   300,283 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 13,517 75,000 SH   DFND   75,000 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 8,427 486,276 SH   DFND   486,276 0 0
INTEL CORP COM 458140100 14,731 427,600 SH   DFND   427,600 0 0
INTEL CORP SDCV 12/1 458140AD2 52,080 40,420,000 PRN   DFND   40,420,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 635 4,251 SH   DFND   4,251 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 30,234 89,363 SH   DFND   89,363 0 0
JPMORGAN CHASE & CO COM 46625H100 8,378 126,879 SH   DFND   126,879 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 11,068 1,433,700 SH   DFND   1,433,700 0 0
LUMBER LIQUIDATORS HLDGS INC COM 55003T107 51,544 2,969,100 SH Put DFND   2,969,100 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 25,341 1,549,113 SH   DFND   1,549,113 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 20,276 2,298,882 SH   DFND   2,298,882 0 0
MEDGENICS INC COM NEW 58436Q203 5,223 867,608 SH   DFND   867,608 0 0
MICROCHIP TECHNOLOGY INC SDCV 2.125%12/1 595017AB0 30,037 15,764,000 PRN   DFND   15,764,000 0 0
MICRON TECHNOLOGY INC NOTE 1.625% 2/1 595112AU7 12,924 9,000,000 PRN   DFND   9,000,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 7,936 251,137 SH   DFND   251,137 0 0
NAVIGATOR HOLDINGS LTD SHS Y62132108 24,090 1,891,962 SH   DFND   1,891,962 0 0
NEW YORK TIMES CO CL A 650111107 28,193 2,100,798 SH   DFND   2,100,798 0 0
NORTHSTAR REALTY EUROPE CORP COM 66706L101 19,477 1,649,225 SH   DFND   1,649,225 0 0
NOVELLUS SYS INC NOTE 2.625% 5/1 670008AD3 68,694 29,193,000 PRN   DFND   29,193,000 0 0
OCERA THERAPEUTICS INC COM 67552A108 2,908 932,086 SH   DFND   932,086 0 0
PALATIN TECHNOLOGIES INC COM PAR $ .01 696077403 2,316 4,982,174 SH   DFND   4,982,174 0 0
PDVWIRELESS INC COM 69290R104 21,693 864,301 SH   DFND   864,301 0 0
PRONAI THERAPEUTICS INC COM 74346L101 1,053 70,000 SH   DFND   70,000 0 0
PTC THERAPEUTICS INC COM 69366J200 3,810 117,600 SH   DFND   117,600 0 0
RADIAN GROUP INC NOTE 2.250% 3/0 750236AN1 21,263 16,405,000 PRN   DFND   16,405,000 0 0
REALOGY HLDGS CORP COM 75605Y106 27,136 740,000 SH   DFND   740,000 0 0
REGENXBIO INC COM 75901B107 5,185 351,525 SH   DFND   351,525 0 0
SANDISK CORP COM 80004C101 29,469 387,805 SH   DFND   387,805 0 0
SAREPTA THERAPEUTICS INC COM 803607100 4,778 123,850 SH   DFND   123,850 0 0
SELECT SECTOR SPDR TR SBI INT-ENERGY 81369Y506 4,524 75,000 SH   DFND   75,000 0 0
SOLARCITY CORP COM 83416T100 20,756 406,816 SH   DFND   406,816 0 0
SOLARCITY CORP COM 83416T100 20,714 406,000 SH Put DFND   406,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 81,548 400,000 SH Put DFND   400,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 392,594 5,592,500 SH Put DFND   5,592,500 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 20,475 900,000 SH Put DFND   900,000 0 0
TEEKAY TANKERS LTD CL A Y8565N102 12,531 1,821,389 SH   DFND   1,821,389 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 23,316 769,520 SH   DFND   769,520 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 3,357 363,292 SH   DFND   363,292 0 0
VERISIGN INC SDCV 3.250% 8/1 92343EAD4 102,966 40,000,000 PRN   DFND   40,000,000 0 0
VIPSHOP HLDGS LTD NOTE 1.500% 3/1 92763WAA1 18,584 17,500,000 PRN   DFND   17,500,000 0 0
WAYFAIR INC CL A 94419L101 9,524 200,000 SH   DFND   200,000 0 0
WAYFAIR INC CL A 94419L101 9,524 200,000 SH Put DFND   200,000 0 0
WELLS FARGO & CO NEW COM 949746101 21,468 394,921 SH   DFND   394,921 0 0
WESCO INTL INC DBCV 6.000% 9/1 95082PAH8 61,446 39,000,000 PRN   DFND   39,000,000 0 0
WL ROSS HLDG CORP COM SHS 92939D104 9,960 1,000,000 SH   DFND   1,000,000 0 0
XENCOR INC COM 98401F105 5,657 386,925 SH   DFND   386,925 0 0
YOUKU TUDOU INC SPONSORED ADR 98742U100 21,853 805,499 SH   DFND   805,499 0 0
YY INC NOTE 2.250% 4/0 98426TAB2 4,874 5,000,000 PRN   DFND   5,000,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 9,979 425,000 SH   DFND   425,000 0 0
ZILLOW GROUP INC CL A 98954M101 9,114 350,000 SH   DFND   350,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 1,409 60,000 SH Put DFND   60,000 0 0