The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 37,488 962,217 SH   DFND   962,217 0 0
ACHILLION PHARMACEUTICALS IN COM 00448Q201 6,316 515,583 SH   DFND   515,583 0 0
ADECOAGRO S A COM L00849106 968 120,800 SH   DFND   120,800 0 0
AGENUS INC COM NEW 00847G705 34,103 9,259,260 SH   DFND   9,259,260 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 6,280 56,048 SH   DFND   56,048 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 8,908 85,700 SH   DFND   85,700 0 0
ALTISOURCE PORTFOLIO SOLNS S REG SHS L0175J104 15,234 450,840 SH   DFND   450,840 0 0
ALTISOURCE PORTFOLIO SOLNS S REG SHS L0175J104 13,019 385,300 SH Put DFND   385,300 0 0
ALTISOURCE RESIDENTIAL CORP CL B 02153W100 9,312 480,000 SH Put DFND   480,000 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 12,060 373,953 SH   DFND   373,953 0 0
ARM HLDGS PLC SPONSORED ADR 042068106 10,191 220,100 SH Put DFND   220,100 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102 12,780 250,000 SH Call DFND   250,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 1,711 361,722 SH   DFND   361,722 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 8,408 9,000,000 PRN   DFND   9,000,000 0 0
ARROWHEAD RESH CORP COM NEW 042797209 27,515 3,779,482 SH   DFND   3,779,482 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 3,867 535,000 SH   DFND   535,000 0 0
AVALANCHE BIOTECHNOLOGIES IN COM 05337G107 5,832 108,000 SH   DFND   108,000 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 15,155 1,246,282 SH   DFND   1,246,282 0 0
BLUEBIRD BIO INC COM 09609G100 14,932 162,800 SH   DFND   162,800 0 0
BRF SA SPONSORED ADR 10552T107 18,856 807,520 SH   DFND   807,520 0 0
CAPITAL ONE FINL CORP COM 14040H105 15,417 186,765 SH   DFND   186,765 0 0
CAPITAL ONE FINL CORP COM 14040H105 8,255 100,000 SH Call DFND   100,000 0 0
CDN IMPERIAL BK COMM TORONTO COM 136069101 6,446 75,000 SH Put DFND   75,000 0 0
CHINA ZENIX AUTO INTL LTD ADS 16951E104 6,778 6,074,805 SH   DFND   6,074,805 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 3,377 259,999 SH   DFND   259,999 0 0
COVIDIEN PLC SHS G2554F113 122,736 1,200,000 SH   DFND   1,200,000 0 0
CTRIP COM INTL LTD NOTE 1.250%10/1 22943FAD2 14,658 15,000,000 PRN   DFND   15,000,000 0 0
CUBIST PHARMACEUTICALS INC COM 229678107 120,780 1,200,000 SH   DFND   1,200,000 0 0
CUBIST PHARMACEUTICALS INC NOTE 1.125% 9/0 229678AF4 12,636 9,500,000 PRN   DFND   9,500,000 0 0
CUBIST PHARMACEUTICALS INC RIGHT 99/99/9999 229678123 18 572,366 SH   DFND   572,366 0 0
CYTRX CORP COM PAR $.001 232828509 14,093 5,143,564 SH   DFND   5,143,564 0 0
DORIAN LPG LTD SHS USD Y2106R110 4,195 302,021 SH   DFND   302,021 0 0
DYAX CORP COM 26746E103 11,440 813,666 SH   DFND   813,666 0 0
E TRADE FINANCIAL CORP NOTE 8/3 269246AZ7 61,491 26,214,000 PRN   DFND   26,214,000 0 0
E TRADE FINANCIAL CORP COM NEW 269246401 8,853 365,000 SH Call DFND   365,000 0 0
EBAY INC COM 278642103 46,510 828,752 SH   DFND   828,752 0 0
EBAY INC COM 278642103 6,308 112,400 SH Call DFND   112,400 0 0
ELONG INC SPONSORED ADR 290138205 4,989 278,036 SH   DFND   278,036 0 0
ENDO HEALTH SOLUTIONS INC NOTE 1.750% 4/1 29264FAB2 24,688 10,000,000 PRN   DFND   10,000,000 0 0
EPIZYME INC COM 29428V104 17,798 943,200 SH   DFND   943,200 0 0
EQUITY COMWLTH COM SH BEN INT 294628102 20,536 800,000 SH   DFND   800,000 0 0
ESSENT GROUP LTD COM G3198U102 3,856 150,000 SH   DFND   150,000 0 0
FEDERAL MOGUL HOLDINGS CORP COM 313549404 251 15,581 SH   DFND   15,581 0 0
FIRST SOLAR INC COM 336433107 4,460 100,000 SH Put DFND   100,000 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 13,457 498,392 SH   DFND   498,392 0 0
GREEN DOT CORP CL A 39304D102 17,621 859,997 SH   DFND   859,997 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 19,398 2,010,186 SH   DFND   2,010,186 0 0
HOME LN SERVICING SOLUTIONS ORD SHS G6648D109 2,854 146,210 SH   DFND   146,210 0 0
HOME LN SERVICING SOLUTIONS ORD SHS G6648D109 9,916 508,000 SH Put DFND   508,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 663 4,251 SH   DFND   4,251 0 0
ISHARES US HOME CONS ETF 464288752 2,588 100,000 SH   DFND   100,000 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 210 693 SH   DFND   693 0 0
JPMORGAN CHASE & CO COM 46625H100 6,258 100,000 SH Call DFND   100,000 0 0
JUNO THERAPEUTICS INC COM 48205A109 1,567 30,000 SH   DFND   30,000 0 0
LIBERTY INTERACTIVE CORP INT COM SER A 53071M104 15,731 534,700 SH   DFND   534,700 0 0
LIBERTY INTERACTIVE CORP LBT VENT COM A 53071M880 5,652 149,842 SH   DFND   149,842 0 0
LOWES COS INC COM 548661107 7,145 103,850 SH   DFND   103,850 0 0
LUMBER LIQUIDATORS HLDGS INC COM 55003T107 49,172 741,548 SH   DFND   741,548 0 0
LUMBER LIQUIDATORS HLDGS INC COM 55003T107 194,951 2,940,000 SH Put DFND   2,940,000 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 41,972 1,614,913 SH   DFND   1,614,913 0 0
MEDIVATION INC COM 58501N101 7,513 75,428 SH   DFND   75,428 0 0
MGIC INVT CORP WIS COM 552848103 2,982 320,000 SH   DFND   320,000 0 0
MGIC INVT CORP WIS COM 552848103 23,415 2,512,300 SH Call DFND   2,512,300 0 0
MICROCHIP TECHNOLOGY INC SDCV 2.125%12/1 595017AB0 69,698 38,944,000 PRN   DFND   38,944,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 8,579 507,184 SH   DFND   507,184 0 0
MOL GLOBAL INC SPONSORED ADR 60845Q105 5,152 1,689,290 SH   DFND   1,689,290 0 0
NATIONSTAR MTG HLDGS INC COM 63861C109 8,457 300,000 SH Put DFND   300,000 0 0
NAVIGATOR HOLDINGS LTD SHS Y62132108 21,774 1,033,900 SH   DFND   1,033,900 0 0
NORTHSTAR ASSET MGMT GROUP I COM 66705Y104 6,074 269,100 SH   DFND   269,100 0 0
NORTHSTAR RLTY FIN CORP COM NEW 66704R704 27,688 1,574,967 SH   DFND   1,574,967 0 0
OCERA THERAPEUTICS INC COM 67552A108 3,815 611,627 SH   DFND   611,627 0 0
OCWEN FINL CORP COM NEW 675746309 3,700 245,000 SH   DFND   245,000 0 0
OCWEN FINL CORP COM NEW 675746309 29,578 1,958,800 SH Put DFND   1,958,800 0 0
ONCOTHYREON INC COM 682324108 9,476 5,044,484 SH   DFND   5,044,484 0 0
PALATIN TECHNOLOGIES INC COM PAR $ .01 696077403 2,259 3,495,336 SH   DFND   3,495,336 0 0
REALOGY HLDGS CORP COM 75605Y106 20,999 472,000 SH   DFND   472,000 0 0
RESTORATION HARDWARE HLDGS I COM 761283100 723 7,531 SH   DFND   7,531 0 0
RETROPHIN INC COM 761299106 15,166 1,267,710 SH   DFND   1,267,710 0 0
SALESFORCE COM INC NOTE 0.750% 1/1 79466LAB0 145,201 52,500,000 PRN   DFND   52,500,000 0 0
SELECT SECTOR SPDR TR SBI INT-ENERGY 81369Y506 7,916 100,000 SH Call DFND   100,000 0 0
SELECT SECTOR SPDR TR SBI INT-FINL 81369Y605 24,730 1,000,000 SH Call DFND   1,000,000 0 0
SOLARCITY CORP NOTE 2.750%11/0 83416TAA8 20,142 18,500,000 PRN   DFND   18,500,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 61,765 300,500 SH Call DFND   300,500 0 0
SUNPOWER CORP DBCV 4.500% 3/1 867652AE9 20,867 17,500,000 PRN   DFND   17,500,000 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 15,919 711,300 SH Put DFND   711,300 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 58,544 1,155,390 SH   DFND   1,155,390 0 0
TREEHOUSE FOODS INC COM 89469A104 11,328 132,450 SH   DFND   132,450 0 0
TRULIA INC NOTE 2.750%12/1 897888AB9 7,260 5,000,000 PRN   DFND   5,000,000 0 0
UNITED THERAPEUTICS CORP DEL NOTE 1.000% 9/1 91307CAF9 61,033 22,500,000 PRN   DFND   22,500,000 0 0
VIPSHOP HLDGS LTD NOTE 1.500% 3/1 92763WAA1 8,396 7,000,000 PRN   DFND   7,000,000 0 0
WALTER ENERGY INC COM 93317Q105 68 49,300 SH   DFND   49,300 0 0
WESCO INTL INC DBCV 6.000% 9/1 95082PAH8 51,520 19,000,000 PRN   DFND   19,000,000 0 0
WL ROSS HLDG CORP COM SHS 92939D104 10,260 1,000,000 SH   DFND   1,000,000 0 0
XENCOR INC COM 98401F105 9,843 651,444 SH   DFND   651,444 0 0
YPF SOCIEDAD ANONIMA SPON ADR CL D 984245100 26,294 993,342 SH   DFND   993,342 0 0