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Note 2 - Significant Accounting Policies (Details Textual) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Sep. 30, 2022
Dec. 23, 2021
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Mar. 31, 2023
Dec. 29, 2022
Sep. 30, 2020
Percentage of Royalty Receivable on Sale of Product Rights   50.00%   30.00%            
Milestone Payment Receivable     $ 0 $ 200,000 $ 0 $ 200,000        
Percentage Of Interest Earned on Outstanding Contract Royalty Asset               11.00%    
Proceeds From Royalty Obligation         0 125,000 $ 0      
Repayments of Convertible Debt         99,873 (0) (0)      
Gain (Loss) on Extinguishment of Debt         4,112 0 0      
Asset Impairment Charges         0 0 0      
Advertising Expense         $ 0 0 $ 800      
Convertible Senior Notes 2023 [Member]                    
Debt Instrument, Interest Rate, Stated Percentage     6.25%   6.25%          
Convertible Senior Notes 2026 [Member]                    
Debt Instrument, Interest Rate, Stated Percentage     5.25%   5.25%         5.25%
Repayments of Convertible Debt     $ 9,100              
Gain (Loss) on Extinguishment of Debt     $ 4,100              
Minimum [Member]                    
Property, Plant and Equipment, Useful Life (Year)     3 years   3 years          
Maximum [Member]                    
Property, Plant and Equipment, Useful Life (Year)     10 years   10 years          
Discontinued Operations, Disposed of by Sale [Member] | Omidria Assets Disposal [Member]                    
Percentage of Royalty Receivable on Sale of Product Rights   50.00%   30.00%            
Milestone Payment Receivable from Sale of Royalty Under Asset Purchase Agreement       $ 200,000   $ 200,000     $ 200,000  
DRI Healthcare Acquisition LP [Member]                    
Proceeds From Royalty Obligation $ 125,000                  
Maximum Royalty Payable Percentage     9.40%   9.40%     9.40%