The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABIVAX SA | SPONSORED ADS | 00370M103 | 35,585,307 | 2,488,483 | SH | DFND | 1,2 | 0 | 2,488,483 | 0 | ||
AEROVATE THERAPEUTICS INC | COM | 008064107 | 26,248,993 | 887,690 | SH | DFND | 1,2 | 0 | 887,690 | 0 | ||
ALPINE IMMUNE SCIENCES INC | COM | 02083G100 | 44,733,700 | 1,128,499 | SH | DFND | 1,2 | 0 | 1,128,499 | 0 | ||
AMICUS THERAPEUTICS INC | COM | 03152W109 | 17,616,990 | 1,495,500 | SH | DFND | 1,2 | 0 | 1,495,500 | 0 | ||
ANAPTYSBIO INC | COM | 032724106 | 22,001,612 | 976,981 | SH | DFND | 1,2 | 0 | 976,981 | 0 | ||
APOGEE THERAPEUTICS INC | COM | 03770N101 | 26,580,000 | 400,000 | SH | DFND | 1,2 | 0 | 400,000 | 0 | ||
ARCELLX INC | COMMON STOCK | 03940C100 | 20,865,000 | 300,000 | SH | DFND | 1,2 | 0 | 300,000 | 0 | ||
ARVINAS INC | COM | 04335A105 | 2,935,545 | 71,113 | SH | DFND | 1,2 | 0 | 71,113 | 0 | ||
AUTOLUS THERAPEUTICS PLC | SPON ADS | 05280R100 | 7,443,335 | 1,166,667 | SH | DFND | 1,2 | 0 | 1,166,667 | 0 | ||
CYTOKINETICS INC | COM NEW | 23282W605 | 14,176,382 | 202,202 | SH | DFND | 1,2 | 0 | 202,202 | 0 | ||
DIANTHUS THERAPEUTICS INC | COM | 252828108 | 18,750,000 | 625,000 | SH | DFND | 1,2 | 0 | 625,000 | 0 | ||
DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 15,697,657 | 1,264,920 | SH | DFND | 1,2 | 0 | 1,264,920 | 0 | ||
ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 21,440,000 | 8,000,000 | SH | DFND | 1,2 | 0 | 8,000,000 | 0 | ||
EVOLUS INC | COM | 30052C107 | 34,300,000 | 2,450,000 | SH | DFND | 1,2 | 0 | 2,450,000 | 0 | ||
HELIX ACQUISITION CORP II | CL A ORD SHS | G4444H101 | 5,200,000 | 500,000 | SH | DFND | 1,2 | 0 | 500,000 | 0 | ||
IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 7,475,000 | 115,000 | SH | DFND | 1,2 | 0 | 115,000 | 0 | ||
INSMED INC | COM PAR $.01 | 457669307 | 21,041,621 | 775,585 | SH | DFND | 1,2 | 0 | 775,585 | 0 | ||
INTRA-CELLULAR THERAPIES INC | COM | 46116X101 | 10,380,000 | 150,000 | SH | DFND | 1,2 | 0 | 150,000 | 0 | ||
JASPER THERAPEUTICS INC | COM NEW | 471871202 | 11,965,668 | 407,550 | SH | DFND | 1,2 | 0 | 407,550 | 0 | ||
KYVERNA THERAPEUTICS INC | COM | 501976104 | 3,726,000 | 150,000 | SH | DFND | 1,2 | 0 | 150,000 | 0 | ||
MERUS N V | COM | N5749R100 | 10,054,659 | 223,288 | SH | DFND | 1,2 | 0 | 223,288 | 0 | ||
MIND MEDICINE MINDMED INC | COM NEW | 60255C885 | 18,800,000 | 2,000,000 | SH | DFND | 1,2 | 0 | 2,000,000 | 0 | ||
NEUROGENE INC | COM | 64135M105 | 51,118,412 | 1,004,291 | SH | DFND | 1,2 | 0 | 1,004,291 | 0 | ||
OCULAR THERAPEUTIX INC | COM | 67576A100 | 15,731,379 | 1,728,723 | SH | DFND | 1,2 | 0 | 1,728,723 | 0 | ||
OPTINOSE INC | COM | 68404V100 | 12,828,024 | 8,786,318 | SH | DFND | 1,2 | 0 | 8,786,318 | 0 | ||
OUTLOOK THERAPEUTICS INC | COM | 69012T305 | 17,671,200 | 1,480,000 | SH | DFND | 1,2 | 0 | 1,480,000 | 0 | ||
PLIANT THERAPEUTICS INC | COM | 729139105 | 27,592,774 | 1,851,864 | SH | DFND | 1,2 | 0 | 1,851,864 | 0 | ||
PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 7,121,228 | 1,343,628 | SH | DFND | 1,2 | 0 | 1,343,628 | 0 | ||
SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 4,741,250 | 125,000 | SH | DFND | 1,2 | 0 | 125,000 | 0 | ||
TERNS PHARMACEUTICALS INC | COM | 880881107 | 8,593,436 | 1,309,975 | SH | DFND | 1,2 | 0 | 1,309,975 | 0 | ||
UROGEN PHARMA LTD | COM | M96088105 | 39,308,175 | 2,620,545 | SH | DFND | 1,2 | 0 | 2,620,545 | 0 | ||
VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 23,375,850 | 1,335,000 | SH | DFND | 1,2 | 0 | 1,335,000 | 0 | ||
VISTAGEN THERAPEUTICS INC | COM | 92840H400 | 9,814,121 | 1,858,735 | SH | DFND | 1,2 | 0 | 1,858,735 | 0 | ||
XENON PHARMACEUTICALS INC | COM | 98420N105 | 19,637,171 | 456,148 | SH | DFND | 1,2 | 0 | 456,148 | 0 | ||
ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | 7,087,392 | 2,757,740 | SH | DFND | 1,2 | 0 | 2,757,740 | 0 |