The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA HEALTHCARE COMPANY IN COM 00404A109 9,974 164,320 SH   DFND 1 164,320 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 652 5,491 SH   DFND 1 5,491 0 0
ALPHABET INC CAP STK CL C 02079K107 8,574 2,963 SH   DFND 1 2,963 0 0
AMAZON COM INC COM 023135106 89,590 26,869 SH   DFND 1 26,869 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 6,229 131,749 SH   DFND 1 131,749 0 0
ARVINAS INC COM 04335A105 18,835 229,300 SH   DFND 1 229,300 0 0
BARINGS BDC INC COM 06759L103 8,815 799,916 SH   DFND 1 799,916 0 0
BILL COM HLDGS INC COM 090043100 19,670 78,950 SH   DFND 1 78,950 0 0
BLACKROCK ESG CAP ALLC TR SHS BEN INT 09262F100 873 46,800 SH   DFND 1 46,800 0 0
BLACKROCK INNOVATION AND GRW SHS BEN INT 09260Q108 2,766 190,264 SH   DFND 1 190,264 0 0
BLACKSTONE SECD LENDING FD COMMON STOCK 09261X102 3,920 115,305 SH   DFND 1 115,305 0 0
BOEING CO COM 097023105 12,512 62,150 SH   DFND 1 62,150 0 0
BOULDER GROWTH & INCOME FD I COM 101507101 1,198 84,312 SH   DFND 1 84,312 0 0
BRANDYWINEGBL GBL INCM OPP F COM 10537L104 315 26,880 SH   DFND 1 26,880 0 0
BROOKDALE SR LIVING INC COM 112463104 931 180,399 SH   DFND 1 180,399 0 0
C4 THERAPEUTICS INC COM STK 12529R107 8,233 255,681 SH   DFND 1 255,681 0 0
CARNIVAL CORP COMMON STOCK 143658300 7,385 367,070 SH   DFND 1 367,070 0 0
CARVANA CO CL A 146869102 18,536 79,969 SH   DFND 1 79,969 0 0
CENTER COAST BRKFLD MLP ENRG SHS BEN INT 151461209 1,455 107,485 SH   DFND 1 107,485 0 0
CHECKMATE PHARMACEUTICALS IN COM 162818108 3,750 1,306,626 SH   DFND 1 1,306,626 0 0
CISCO SYS INC COM 17275R102 4,037 63,700 SH   DFND 1 63,700 0 0
COHEN & STEERS REIT & PFD & COM 19247X100 487 17,000 SH   DFND 1 17,000 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 13,628 1,023,859 SH   DFND 1 1,023,859 0 0
COMMUNITY HEALTHCARE TR INC COM 20369C106 3,295 69,700 SH   DFND 1 69,700 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 6,123 80,800 SH Call DFND 1 80,800 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 8,033 106,007 SH   DFND 1 106,007 0 0
CUSHING MLP & INFRASTRUCT COM NEW 231631300 1,132 37,100 SH   DFND 1 37,100 0 0
D R HORTON INC COM 23331A109 48,510 447,300 SH   DFND 1 447,300 0 0
DBX ETF TR XTRACK HRVST CSI 233051879 5,125 131,100 SH   DFND 1 131,100 0 0
DELAWARE IVY HIGH INCOME OPP COM 246107106 518 37,200 SH   DFND 1 37,200 0 0
DOUBLELINE INCOME SOLUTIONS COM 258622109 1,033 64,100 SH   DFND 1 64,100 0 0
DOXIMITY INC CL A 26622P107 16,307 325,300 SH   DFND 1 325,300 0 0
EATON VANCE ENHANCED EQUITY COM 278277108 270 11,000 SH   DFND 1 11,000 0 0
EATON VANCE TAX ADVT DIV INC COM 27828G107 283 9,500 SH   DFND 1 9,500 0 0
EATON VANCE TX ADV GLBL DIV COM 27828S101 223 9,806 SH   DFND 1 9,806 0 0
EQUITABLE HLDGS INC COM 29452E101 40,473 1,234,300 SH   DFND 1 1,234,300 0 0
FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 57,252 1,097,200 SH   DFND 1 1,097,200 0 0
FIRST AMERN FINL CORP COM 31847R102 70,409 900,030 SH   DFND 1 900,030 0 0
FIVE9 INC COM 338307101 21,495 156,530 SH   DFND 1 156,530 0 0
FRANKLIN UNVL TR SH BEN INT 355145103 177 20,937 SH   DFND 1 20,937 0 0
GODADDY INC CL A 380237107 11,032 130,000 SH   DFND 1 130,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 3,333 3,500,000 PRN   DFND 1 3,500,000 0 0
GUGGENHEIM STRATEGIC OPPORTU COM SBI 40167F101 2,923 159,528 SH   DFND 1 159,528 0 0
HCA HEALTHCARE INC COM 40412C101 9,318 36,270 SH   DFND 1 36,270 0 0
HERTZ GLOBAL HLDGS INC COM NEW 42806J700 4,971 198,900 SH   DFND 1 198,900 0 0
HERTZ GLOBAL HLDGS INC W EXP 06/30/205 42806J148 12,655 793,400 SH   DFND 1 793,400 0 0
HERZFELD CARIBBEAN BASIN FD COM 42804T106 112 20,213 SH   DFND 1 20,213 0 0
HIGH INCOME SECS FD SHS BEN INT 42968F108 273 31,510 SH   DFND 1 31,510 0 0
HIGHLAND GLOBAL ALLOCATION F COM 43010T104 838 92,400 SH   DFND 1 92,400 0 0
HOLOGIC INC COM 436440101 17,457 228,020 SH   DFND 1 228,020 0 0
HUBSPOT INC COM 443573100 16,518 25,060 SH   DFND 1 25,060 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 11,225 95,375 SH   DFND 1 95,375 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 19,453 152,690 SH   DFND 1 152,690 0 0
JD.COM INC SPON ADR CL A 47215P106 799 11,400 SH   DFND 1 11,400 0 0
JOHNSON & JOHNSON COM 478160104 26,360 154,090 SH   DFND 1 154,090 0 0
KB HOME COM 48666K109 10,847 242,500 SH   DFND 1 242,500 0 0
KYMERA THERAPEUTICS INC COM 501575104 17,206 271,000 SH   DFND 1 271,000 0 0
LAM RESEARCH CORP COM 512807108 45,529 63,310 SH   DFND 1 63,310 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 9,091 195,052 SH   DFND 1 195,052 0 0
LENNAR CORP CL A 526057104 36,004 309,949 SH   DFND 1 309,949 0 0
LIBERTY ALL STAR EQUITY FD SH BEN INT 530158104 1,793 213,952 SH   DFND 1 213,952 0 0
LILLY ELI & CO COM 532457108 3,318 12,013 SH   DFND 1 12,013 0 0
MCKESSON CORP COM 58155Q103 18,225 73,320 SH   DFND 1 73,320 0 0
MERCK & CO INC COM 58933Y105 20,271 264,500 SH   DFND 1 264,500 0 0
MICRON TECHNOLOGY INC COM 595112103 83,025 891,300 SH   DFND 1 891,300 0 0
MICROSOFT CORP COM 594918104 77,848 231,470 SH   DFND 1 231,470 0 0
MILLER HOWARD HIGH INC EQTY COM SHS BEN IN 600379101 3,382 327,704 SH   DFND 1 327,704 0 0
MIRATI THERAPEUTICS INC COM 60468T105 14,736 100,455 SH   DFND 1 100,455 0 0
NETEASE INC SPONSORED ADS 64110W102 427 4,200 SH   DFND 1 4,200 0 0
NEUBERGER BERMAN NEXT GENERA COMMON STOCK 64133Q108 3,559 205,700 SH   DFND 1 205,700 0 0
NURIX THERAPEUTICS INC COM 67080M103 13,695 473,048 SH   DFND 1 473,048 0 0
OXFORD LANE CAP CORP COM 691543102 886 114,900 SH   DFND 1 114,900 0 0
PENNYMAC FINL SVCS INC NEW COM 70932M107 79,796 1,143,540 SH   DFND 1 1,143,540 0 0
PFIZER INC COM 717081103 6,147 104,090 SH   DFND 1 104,090 0 0
PHYSICIANS RLTY TR COM 71943U104 1,770 94,000 SH   DFND 1 94,000 0 0
PIMCO GLOBAL STOCKSPLS INCM COM 722011103 825 76,200 SH   DFND 1 76,200 0 0
PINDUODUO INC SPONSORED ADS 722304102 251 4,300 SH   DFND 1 4,300 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 21,584 250,800 SH   DFND 1 250,800 0 0
REDWOOD TR INC COM 758075402 19,136 1,450,800 SH   DFND 1 1,450,800 0 0
REDWOOD TRUST INC NOTE 4.750% 8/1 758075AC9 2,018 1,978,000 PRN   DFND 1 1,978,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 16,445 26,040 SH   DFND 1 26,040 0 0
RIVERNORTH FLEXIBLE MUNI INC COM 76883Y107 385 19,395 SH   DFND 1 19,395 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 8,793 114,347 SH   DFND 1 114,347 0 0
SABA CAPITAL INCOME & OPRNT SHARES 78518H103 2,523 558,188 SH   DFND 1 558,188 0 0
SALIENT MIDSTREAM & MLP FD SH BEN INT 79471V105 641 95,038 SH   DFND 1 95,038 0 0
SERVICENOW INC COM 81762P102 10,850 16,715 SH   DFND 1 16,715 0 0
SHOPIFY INC CL A 82509L107 17,011 12,350 SH   DFND 1 12,350 0 0
STARWOOD PPTY TR INC COM 85571B105 20,611 848,200 SH   DFND 1 848,200 0 0
STARWOOD PPTY TR INC NOTE 4.375% 4/0 85571BAH8 11,306 10,815,000 PRN   DFND 1 10,815,000 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 38,331 318,600 SH   DFND 1 318,600 0 0
TELADOC HEALTH INC COM 87918A105 8,636 94,050 SH   DFND 1 94,050 0 0
TELADOC HEALTH INC NOTE 1.250% 6/0 87918AAF2 643 700,000 PRN   DFND 1 700,000 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 9,345 114,400 SH   DFND 1 114,400 0 0
TESLA INC COM 88160R101 72,832 68,919 SH   DFND 1 68,919 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 10,420 15,617 SH   DFND 1 15,617 0 0
THORNBURG INCM BUILDER OPP T COM 885213108 881 47,200 SH   DFND 1 47,200 0 0
T-MOBILE US INC COM 872590104 11,370 98,030 SH   DFND 1 98,030 0 0
TORTOISE MIDSTRM ENERGY FD I COM 89148B200 769 25,219 SH   DFND 1 25,219 0 0
TRANSDIGM GROUP INC COM 893641100 18,156 28,534 SH   DFND 1 28,534 0 0
TWO HARBORS INVENTMENT CORPO NOTE 6.250% 1/1 90187BAA9 1,799 1,799,000 PRN   DFND 1 1,799,000 0 0
VANECK ETF TRUST PHARMACEUTCL ETF 92189F692 5,372 69,800 SH   DFND 1 69,800 0 0
VERACYTE INC COM 92337F107 7,567 183,660 SH   DFND 1 183,660 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 23,521 107,110 SH   DFND 1 107,110 0 0
VIACOMCBS INC CL B 92556H206 14,103 467,300 SH   DFND 1 467,300 0 0
VIRTUS ALLIANZGI EQUITY & CO COM 92841M101 901 29,900 SH   DFND 1 29,900 0 0
VISA INC COM CL A 92826C839 5,843 26,960 SH   DFND 1 26,960 0 0
WALKER & DUNLOP INC COM 93148P102 13,689 90,730 SH   DFND 1 90,730 0 0
WESTERN ASSET DIVERSIFIED IN COM SHS BEN INT 95790K109 875 47,800 SH   DFND 1 47,800 0 0
WESTERN AST INFL LKD OPP & I COM 95766R104 866 63,800 SH   DFND 1 63,800 0 0
YUM CHINA HLDGS INC COM 98850P109 368 7,500 SH   DFND 1 7,500 0 0
ZOETIS INC CL A 98978V103 9,195 37,681 SH   DFND 1 37,681 0 0