The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADAMS EXPRESS CO COM 006212104 3,339 219,530 SH   DFND 1 219,530 0 0
ADVENT CLAY CONV SEC INC FD COM 007639107 755 121,061 SH   DFND 1 121,061 0 0
ADVENT CLAYMORE ENH GRW & IN COM 00765E104 924 107,293 SH   DFND 1 107,293 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 10,853 77,359 SH   DFND 1 77,359 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 51,778 299,800 SH   DFND 1 299,800 0 0
ALIGN TECHNOLOGY INC COM 016255101 18,658 100,165 SH   DFND 1 100,165 0 0
ALLERGAN PLC SHS G0177J108 5,185 25,300 SH   DFND 1 25,300 0 0
ALPINE TOTAL DYNAMIC DIVID F COM SH BEN INT N 021060207 157 17,395 SH   DFND 1 17,395 0 0
ALTABA INC COM 021346101 25,522 385,300 SH   DFND 1 385,300 0 0
ALTICE USA INC COM 02156K103 4,880 178,700 SH   DFND 1 178,700 0 0
AMAZON COM INC COM 023135106 23,887 24,847 SH   DFND 1 24,847 0 0
AMC ENTMT HLDGS INC CL A COM 00165C104 212 14,400 SH   DFND 1 14,400 0 0
AMERCO COM 023586100 13,350 35,610 SH   DFND 1 35,610 0 0
APPLE INC COM 037833100 54,128 351,210 SH   DFND 1 351,210 0 0
ARBOR RLTY TR INC COM 038923108 1,413 172,300 SH   DFND 1 172,300 0 0
ARES CAP CORP COM 04010L103 46,551 2,840,200 SH   DFND 1 2,840,200 0 0
BAIDU INC SPON ADR REP A 056752108 9,889 39,924 SH   DFND 1 39,924 0 0
BANK AMER CORP COM 060505104 63,711 2,514,258 SH   DFND 1 2,514,258 0 0
BAOZUN INC SPONSORED ADR 06684L103 6,254 190,900 SH   DFND 1 190,900 0 0
BIOGEN INC COM 09062X103 16,493 52,672 SH   DFND 1 52,672 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 4,527 48,645 SH   DFND 1 48,645 0 0
BIOVERATIV INC COM 09075E100 9,753 170,900 SH   DFND 1 170,900 0 0
BLACKROCK MUNI INTER DR FD I COM 09253X102 177 12,500 SH   DFND 1 12,500 0 0
BLACKSTONE MTG TR INC COM CL A 09257W100 36,287 1,169,800 SH   DFND 1 1,169,800 0 0
BLUEBIRD BIO INC COM 09609G100 714 5,200 SH   DFND 1 5,200 0 0
BOSTON SCIENTIFIC CORP COM 101137107 7,508 257,400 SH   DFND 1 257,400 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 12,490 195,960 SH   DFND 1 195,960 0 0
BROADCOM LTD SHS Y09827109 41,768 172,212 SH   DFND 1 172,212 0 0
CABLE ONE INC COM 12685J105 5,064 7,012 SH   DFND 1 7,012 0 0
CARDIOME PHARMA CORP COM NO PAR 14159U301 6,132 2,878,985 SH   DFND 1 2,878,985 0 0
CARTER INC COM 146229109 272 2,750 SH   DFND 1 2,750 0 0
CARVANA CO CL A 146869102 11,298 769,650 SH   DFND 1 769,650 0 0
CELGENE CORP COM 151020104 10,331 70,847 SH   DFND 1 70,847 0 0
CHILDRENS PL INC COM 168905107 236 2,000 SH   DFND 1 2,000 0 0
CITIGROUP INC W EXP 01/04/201 172967226 31 271,800 SH   DFND 1 271,800 0 0
CITIGROUP INC COM NEW 172967424 63,032 866,543 SH   DFND 1 866,543 0 0
CLOVIS ONCOLOGY INC COM 189464100 6,900 83,735 SH   DFND 1 83,735 0 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 23,858 328,900 SH   DFND 1 328,900 0 0
COMMUNITY HEALTHCARE TR INC COM 20369C106 6,214 230,500 SH   DFND 1 230,500 0 0
CORNERSTONE STRATEGIC VALUE COM 21924B302 1,856 125,319 SH   DFND 1 125,319 0 0
CORNERSTONE TOTAL RTRN FD IN COM 21924U300 1,805 123,400 SH   DFND 1 123,400 0 0
CREDIT ACCEP CORP MICH COM 225310101 24,083 85,959 SH   DFND 1 85,959 0 0
CREDIT SUISSE NASSAU BRH VELOCITY SHS SHR 22542D357 181 16,000 SH   DFND 1 16,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 13,937 779,931 SH   DFND 1 779,931 0 0
CTRIP COM INTL LTD AMERICAN DEP SHS 22943F100 12,783 242,370 SH   DFND 1 242,370 0 0
CYPRESS SEMICONDUCTOR CORP COM 232806109 25,463 1,695,300 SH   DFND 1 1,695,300 0 0
D R HORTON INC COM 23331A109 34,559 865,495 SH   DFND 1 865,495 0 0
DERMIRA INC COM 24983L104 5,761 213,385 SH   DFND 1 213,385 0 0
DIVIDEND & INCOME FUND COM NEW 25538A204 459 35,700 SH   DFND 1 35,700 0 0
DOMINION RES INC VA NEW COM 25746U109 4,924 64,000 SH   DFND 1 64,000 0 0
EATON VANCE RISK MNGD DIV EQ COM 27829G106 110 11,700 SH   DFND 1 11,700 0 0
ELLIE MAE INC COM 28849P100 9,617 117,100 SH   DFND 1 117,100 0 0
EVERSOURCE ENERGY COM 30040W108 5,010 82,900 SH   DFND 1 82,900 0 0
EXPRESS SCRIPTS HLDG CO COM 30219G108 23,536 371,700 SH   DFND 1 371,700 0 0
FACEBOOK INC CL A 30303M102 39,608 231,800 SH   DFND 1 231,800 0 0
FIRSTHAND TECH VALUE FD INC COM 33766Y100 179 22,400 SH   DFND 1 22,400 0 0
FRANKLIN LTD DURATION INC TR COM 35472T101 121 10,100 SH   DFND 1 10,100 0 0
FRANKLIN RES INC COM 354613101 9,596 215,600 SH   DFND 1 215,600 0 0
GALAPAGOS NV SPON ADR 36315X101 7,372 72,453 SH   DFND 1 72,453 0 0
GLOBAL MED REIT INC COM NEW 37954A204 5,613 625,000 SH   DFND 1 625,000 0 0
GOLDMAN SACHS BDC INC SHS 38147U107 1,000 43,800 SH   DFND 1 43,800 0 0
GOLUB CAP BDC INC COM 38173M102 12,791 679,666 SH   DFND 1 679,666 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 8,725 85,971 SH   DFND 1 85,971 0 0
HERCULES TECH GROWTH CAP INC COM 427096508 173 13,400 SH   DFND 1 13,400 0 0
HOLOGIC INC COM 436440101 6,331 172,548 SH   DFND 1 172,548 0 0
HOME DEPOT INC COM 437076102 343 2,100 SH   DFND 1 2,100 0 0
IMAX CORP COM 45245E109 359 15,860 SH   DFND 1 15,860 0 0
INCYTE CORP COM 45337C102 432 3,700 SH   DFND 1 3,700 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 10,395 658,750 SH   DFND 1 658,750 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 514 9,900 SH   DFND 1 9,900 0 0
ISHARES TR CORE S&P500 ETF 464287200 354 1,400 SH   DFND 1 1,400 0 0
ISHARES TR MSCI INDIA ETF 46429B598 2,296 69,900 SH   DFND 1 69,900 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 790 5,400 SH   DFND 1 5,400 0 0
JD COM INC SPON ADR CL A 47215P106 17,557 459,600 SH   DFND 1 459,600 0 0
JPMORGAN CHASE & CO COM 46625H100 30,831 322,800 SH   DFND 1 322,800 0 0
KERYX BIOPHARMACEUTICALS INC COM 492515101 5,333 751,101 SH   DFND 1 751,101 0 0
KURA ONCOLOGY INC COM 50127T109 3,362 224,861 SH   DFND 1 224,861 0 0
LADDER CAP CORP CL A 505743104 10,980 796,778 SH   DFND 1 796,778 0 0
LAM RESEARCH CORP COM 512807108 53,266 287,860 SH   DFND 1 287,860 0 0
LEGG MASON BW GLB INC OPP FD COM 52469B100 173 12,907 SH   DFND 1 12,907 0 0
LENNAR CORP CL A 526057104 14,784 279,997 SH   DFND 1 279,997 0 0
LIBERTY BROADBAND CORP COM SER C 530307305 53,515 561,545 SH   DFND 1 561,545 0 0
LIBERTY INTERACTIVE CORP LBT VEN COM A NE 53071M856 60,013 1,042,792 SH   DFND 1 1,042,792 0 0
LOGMEIN INC COM 54142L109 13,693 124,424 SH   DFND 1 124,424 0 0
MERCK & CO INC NEW COM 58933Y105 21,424 334,600 SH   DFND 1 334,600 0 0
MICRON TECHNOLOGY INC COM 595112103 14,167 360,200 SH   DFND 1 360,200 0 0
MICROSEMI CORP COM 595137100 5,822 113,100 SH   DFND 1 113,100 0 0
MICROSOFT CORP COM 594918104 27,613 370,700 SH   DFND 1 370,700 0 0
MORGAN STANLEY CHINA A SH FD COM 617468103 837 35,100 SH   DFND 1 35,100 0 0
NATIONAL GRID PLC SPONSORED ADR NE 636274409 2,633 41,983 SH   DFND 1 41,983 0 0
NEUBERGER BERMAN INTER MUNI COM 64124P101 277 18,047 SH   DFND 1 18,047 0 0
NEUBERGER BERMAN RE ES SEC F COM 64190A103 113 20,100 SH   DFND 1 20,100 0 0
NEXPOINT CR STRATEGIES FD COM NEW 65340G205 354 15,353 SH   DFND 1 15,353 0 0
ORBOTECH LTD ORD M75253100 2,282 54,061 SH   DFND 1 54,061 0 0
PACIRA PHARMACEUTICALS INC COM 695127100 6,902 183,800 SH   DFND 1 183,800 0 0
PENNYMAC MTG INVT TR COM 70931T103 15,899 914,272 SH   DFND 1 914,272 0 0
PFIZER INC COM 717081103 12,913 361,700 SH   DFND 1 361,700 0 0
PHYSICIANS RLTY TR COM 71943U104 2,411 136,000 SH   DFND 1 136,000 0 0
PIONEER HIGH INCOME TR COM 72369H106 694 69,300 SH   DFND 1 69,300 0 0
POOL CORPORATION COM 73278L105 292 2,700 SH   DFND 1 2,700 0 0
PRESTIGE BRANDS HLDGS INC COM 74112D101 1,599 31,930 SH   DFND 1 31,930 0 0
PULTE GROUP INC COM 745867101 23,460 858,394 SH   DFND 1 858,394 0 0
REGAL ENTMT GROUP CL A 758766109 174 10,900 SH   DFND 1 10,900 0 0
SALESFORCE COM INC COM 79466L302 20,263 216,900 SH   DFND 1 216,900 0 0
SERVICE CORP INTL COM 817565104 6,889 199,668 SH   DFND 1 199,668 0 0
SIENNA BIOPHARMACEUTICALS IN COM 82622H108 16,421 751,209 SH   DFND 1 751,209 0 0
SOLAR CAP LTD COM 83413U100 17,849 824,831 SH   DFND 1 824,831 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 377 1,500 SH   DFND 1 1,500 0 0
STARWOOD PPTY TR INC COM 85571B105 54,995 2,531,982 SH   DFND 1 2,531,982 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 1,299 34,600 SH   DFND 1 34,600 0 0
TOLL BROTHERS INC COM 889478103 336 8,100 SH   DFND 1 8,100 0 0
TPG SPECIALTY LENDING INC COM 87265K102 8,396 400,563 SH   DFND 1 400,563 0 0
TRI POINTE HOMES INC COM 87265H109 6,867 497,271 SH   DFND 1 497,271 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 9,561 62,882 SH   DFND 1 62,882 0 0
VIASAT INC COM 92552V100 31,871 495,501 SH   DFND 1 495,501 0 0
VIRTUS TOTAL RETURN FUND INC COM 92837G100 558 42,791 SH   DFND 1 42,791 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 4,539 208,703 SH   DFND 1 208,703 0 0
WAYFAIR INC CL A 94419L101 229 3,400 SH   DFND 1 3,400 0 0
WELLS FARGO ADV GLB DIV OPP COM 94987C103 94 15,025 SH   DFND 1 15,025 0 0
WELLS FARGO ADVANTAGE MULTI COM SHS 94987D101 489 36,445 SH   DFND 1 36,445 0 0
WESTERN ASSET CORPORATE LN F COM 95790J102 149 13,672 SH   DFND 1 13,672 0 0
WISDOMTREE TR INDIA ERNGS FD 97717W422 5,545 220,300 SH   DFND 1 220,300 0 0
YELP INC CL A 985817105 26,553 613,229 SH   DFND 1 613,229 0 0