EXHIBIT 32.1

REYNOLDS AMERICAN INC.

Certification Pursuant to 18 U.S.C. §1350

               Pursuant to 18 U.S.C. §1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, each of the undersigned, Susan M. Ivey, President and Chief Executive Officer, and Dianne M. Neal, Executive Vice President and Chief Financial Officer, of Reynolds American Inc., hereby certifies, to her knowledge, that:

1)	RAI’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2005, fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and
2)	the information contained in RAI’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2005, fairly presents, in all material respects, the financial condition and results of operations of RAI.
	EXECUTED this 3rd day of November, 2005.

/s/ Susan M. Ivey  

Susan M. Ivey, President and Chief Executive Officer of Reynolds 

American Inc. 

/s/ Dianne M. Neal  

Dianne M. Neal, Executive Vice President and Chief
Financial Officer of Reynolds American Inc.