CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Cash flows from operating activities
Net loss	$ (141,405)	$ (19,816)
Adjustments to reconcile net loss income to net cash used in operating activities:
Gain from sale of PRV, net of transaction costs		(107,375)
Depreciation and amortization	551	418
Amortization of debt issuance costs	2,248	1,663
Accretion of revenue interest financing debt	4,806	956
Amortization of discount on short-term investments	(1,241)
Stock-based compensation expense	15,563	14,890
Amortization of net contract asset/liability	(1,353)	(1,052)
Noncash lease expense	187	251
Noncash lease liability	413	344
Write off of fixed assets	61	828
Issuance of common stock for cost of license agreement		1,169
Unrealized loss on foreign currency transactions		930
Changes in operating assets and liabilities:
Refund liability		(22,163)
Net contract asset/liability	2,613	17,894
Prepaid expenses and other current assets, non-current assets, inventory and accounts receivable	(2,552)	(5,577)
Accounts payable and accrued expenses	2,108	3,754
Net cash used in operating activities	(118,001)	(112,886)
Cash flows from investing activities
Proceeds from sale of PRV, net of transaction costs		107,375
Proceeds from sale of property and equipment	9	171
Maturities of short-term investments	23,500
Purchases of short-term investments	(51,995)
Purchases of property and equipment	(119)	(1,774)
Net cash (used in) provided by investing activities	(28,605)	105,772
Cash flows from financing activities
Proceeds from exercise of stock options	804	1,794
Proceeds from notes payable, net of fees		28,588
Proceeds from revenue interest financing agreement, net of issuance costs		29,921
Proceeds from equity offerings, net of offering costs	25,823	64,477
Other cash flows from financing activities		(42)
Net cash provided by financing activities	26,627	124,738
Net (decrease) increase in cash and cash equivalents	(119,979)	117,624
Cash and cash equivalents-beginning of period	240,551	122,927
Cash and cash equivalents-end of period	120,572	240,551
Supplemental disclosure of cash flow information
Increase in right-of-use asset and liability	66
Property and equipment in accrued expenses		22
Cash paid for interest during the year	8,697	7,892
Cash paid for income taxes during the year	$ 903
Property and equipment in deposits placed in service		$ 1,664