CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities
Net income (loss)	$ 14,496	$ (70,471)
Adjustments to reconcile net loss to net cash used in operating activities:
Gain from sale of PRV, net of transaction costs	(107,375)
Depreciation and amortization	336	262
Amortization of debt issuance costs	1,133	319
Stock-based compensation expense	11,091	10,867
Amortization of net contract asset/liability	(1,000)	(41)
Noncash lease expense	194	232
Noncash lease liability	252	237
Write off of fixed assets	169
Issuance of common stock for cost of license agreement	1,169
Unrealized loss on foreign currency transactions	930
Changes in operating assets and liabilities:
Refund liability	(22,163)	21,828
Net contract asset/liability	11,057	(1,018)
Prepaid expenses and other current assets, non-current assets, inventory and accounts receivable	(2,313)	(453)
Accounts payable, accrued expenses and other long term-liabilities	1,052	4,511
Net cash used in operating activities	(90,972)	(33,727)
Cash flows from investing activities
Proceeds from sale of PRV, net of transaction costs	107,375
Maturities of short-term investments		1,474
Deposit on property and equipment		(1,329)
Purchases of property and equipment	(1,682)	(839)
Net cash provided by (used in) investing activities	105,693	(694)
Cash flows from financing activities
Proceeds from exercise of stock options	1,763	902
Proceeds from notes payable, net of upfront fee	28,838	40,259
Financing costs, paid		(148)
Net cash provided by financing activities	30,601	41,013
Net increase in cash and cash equivalents	45,322	6,592
Cash and cash equivalents-beginning of period	122,927	138,509
Cash and cash equivalents-end of period	168,249	145,101
Supplemental disclosure of cash flow information
Debt issuance costs included in accrued expenses		900
Property and equipment in accrued expenses		$ 107
Property and equipment in deposits placed in service	$ 1,665