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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Revenues                      
Product revenues, net $ 74,203 $ 72,942 $ 75,040 $ 74,516 $ 73,427 $ 70,176 $ 73,061 $ 63,749 $ 296,701 $ 280,413 $ 28,476
Costs and expenses                      
Cost of product revenues 49,088 46,754 48,654 49,164 29,726 46,007 46,838 43,106 193,660 165,677 2,595
Research and development 2,398 2,491 2,459 2,992 2,249 1,907 2,237 2,268 10,340 8,661 8,572
Selling, general and administrative 25,090 30,072 28,935 32,352 30,451 33,448 31,279 31,582 116,449 126,760 92,756
Total costs and expenses 76,576 79,317 80,048 84,508 62,426 81,362 80,354 76,956 320,449 301,098 103,923
Loss from operations (2,373) (6,375) (5,008) (9,992) 11,001 (11,186) (7,293) (13,207) (23,748) (20,685) (75,447)
Interest expense (211) (228) (236) (234) (2,404) (5,868) (6,158) (5,700) (909) (20,130)  
Interest income 383 494 532 526 489 552 391 255 1,935 1,687 582
Net loss $ (2,201) $ (6,109) $ (4,712) $ (9,700) $ 9,086 $ (16,502) $ (13,060) $ (18,652) $ (22,722) $ (39,128) $ (74,865)
Loss per share - basic and diluted $ (0.07) $ (0.18) $ (0.14) $ (0.29)         $ (0.68) $ (1.19) $ (2.47)
Weighted-average shares - basic and diluted (in shares) 33,600,566 33,481,923 33,397,709 33,331,917         33,453,844 32,953,808 30,265,262