March 21, 2013

VIA EDGAR

Securities and Exchange Commission

Division of Investment Management

100 F Street, N.E.

Washington, D.C. 20549

Re: Nuveen Municipal High Income Opportunity Fund

Registration Statement on Form N-14 8C

(File No. 333-186450)

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, the undersigned hereby request that the effective date for Pre-Effective Amendment No. 1 to the Registration Statement on Form N-14 8C referenced above be accelerated so that it will become effective as of Monday, March 25, 2013 or as soon thereafter as practicable.

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Sincerely,

NUVEEN MUNICIPAL HIGH INCOME OPPORTUNITY FUND	NUVEEN SECURITIES, LLC
By:        /s/Kevin J. McCarthy                             Name:  Kevin J. McCarthy Title:    Vice President and Secretary	By:        /s/Kevin J. McCarthy                             Name:  Kevin J. McCarthy Title:    Managing Director