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Loan and Security Agreements - Oxford Loan and Hercules Loan (Details)
1 Months Ended 6 Months Ended
Feb. 28, 2015
USD ($)
$ / shares
shares
Dec. 31, 2012
USD ($)
installment
$ / shares
shares
Jun. 30, 2017
USD ($)
installment
$ / shares
shares
Aug. 31, 2016
USD ($)
Warrants | Common stock warrants | Hercules Capital, Inc.        
Loan and Security Agreements        
Common stock that can be purchased with warrants (in shares) | shares 180,274      
Exercise price of warrants (in dollars per share) | $ / shares $ 5.89      
Significant assumptions used in preparing the option pricing model for valuing the Company's warrants        
Volatility (as a percent) 75.00%      
Risk free interest rate (as a percent) 1.22%      
Life of treasury bonds 4 years      
Strike price (in dollars per share) | $ / shares $ 5.89      
Fair value of common stock (in dollars per share) | $ / shares $ 9.82      
Expected life (in years) 4 years      
Additional Paid-in Capital | Hercules Capital, Inc.        
Loan and Security Agreements        
Fair value of common stock warrant issued with debt financing $ 1,200,000      
Warrants | Common stock warrants        
Loan and Security Agreements        
Common stock that can be purchased with warrants (in shares) | shares     62,505  
Exercise price of warrants (in dollars per share) | $ / shares     $ 6.00  
Warrants | Common stock warrants | Oxford Finance LLC        
Loan and Security Agreements        
Common stock that can be purchased with warrants (in shares) | shares   62,505    
Exercise price of warrants (in dollars per share) | $ / shares   $ 6.00    
Secured debt | Oxford Loan | Oxford Finance LLC        
Loan and Security Agreements        
Amount borrowed   $ 15,000,000    
Number of consecutive monthly principal installments | installment   30    
Final payment   $ 675,000    
Repayment of existing debt 15,500,000      
Secured debt | Hercules Loan | Hercules Capital, Inc.        
Loan and Security Agreements        
Maximum borrowing capacity 25,000,000      
Facility Fee       $ 165,000
Fixed interest rate (as a percent)     9.00%  
Number of consecutive monthly principal installments | installment     23  
Final payment     $ 610,500  
Prepayment premium as percentage of outstanding principal     1.00%  
Discount on debt 1,200,000      
Secured debt | Hercules Loan Tranche One | Hercules Capital, Inc.        
Loan and Security Agreements        
Amount borrowed 16,500,000      
Secured debt | Hercules Loan Tranche Two | Hercules Capital, Inc.        
Loan and Security Agreements        
Additional amount available     $ 8,500,000  
Secured debt | LIBOR | Oxford Loan | Oxford Finance LLC        
Loan and Security Agreements        
Interest rate (as a percent)   9.20%    
Variable rate basis   Three-month U.S. Libor rate    
Variable rate base (as a percent)   0.47%    
Variable interest rate margin (as a percent)   8.73%    
Secured debt | Prime | Hercules Loan | Hercules Capital, Inc.        
Loan and Security Agreements        
Variable rate basis     Prime minus 4.25%  
Variable interest rate margin (as a percent)     9.00%  
Variable rate adjustment (as a percent)     4.25%  
Equity financings | Right to participate in future equity financings | Hercules Capital, Inc. | Maximum        
Loan and Security Agreements        
Equity financings amount $ 2,000,000