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Share-Based Compensation (Details 2) (USD $) In Thousands, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Share-based compensation expense
Total share-based compensation	$ 714	$ 286	$ 1,570	$ 1,213
Share-based compensation expense related to deferred compensation arrangements for non-employee directors			74	88
Research and development expenses
Share-based compensation expense
Total share-based compensation	353	(158)	695	361
General and administrative expenses
Share-based compensation expense
Total share-based compensation	361	444	875	852
Non-employee Directors \| General and administrative expenses
Share-based compensation expense
Share-based compensation expense related to deferred compensation arrangements for non-employee directors	$ 32	$ 43	$ 74	$ 88

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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- Definition

The compensation expense recognized during the period pertaining to the deferred compensation arrangement.

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