The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101   82,854 885 SH   SOLE   885 0 0
908 DEVICES INC COM 65443P102   5,559,928 834,824 SH   SOLE   806,195 0 28,629
ABSCI CORPORATION COM 00091E109   1,724,802 1,306,668 SH   SOLE   1,306,668 0 0
AC IMMUNE SA SHS H00263105   3,769,017 1,322,462 SH   SOLE   1,322,462 0 0
ADOBE INC COM 00724F101   7,849,401 15,394 SH   SOLE   15,394 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   68,665,119 791,620 SH   SOLE   720,315 0 71,305
ALLAKOS INC COM 01671P100   1,441,502 635,023 SH   SOLE   635,023 0 0
ALLEGION PLC ORD SHS G0176J109   3,283,029 31,507 SH   SOLE   31,507 0 0
ALLISON TRANSMISSION HLDGS I COM 01973R101   197,201 3,339 SH   SOLE   3,339 0 0
ALPHA TEKNOVA INC COM 02080L102   2,328,336 834,529 SH   SOLE   834,529 0 0
ALPHABET INC CAP STK CL A 02079K305   12,932,501 98,827 SH   SOLE   98,827 0 0
ALPHABET INC CAP STK CL C 02079K107   58,920,996 446,879 SH   SOLE   446,879 0 0
ALTIMMUNE INC COM NEW 02155H200   247,211 95,081 SH   SOLE   95,081 0 0
AMAZON COM INC COM 023135106   2,874,565 22,613 SH   SOLE   22,613 0 0
AMEREN CORP COM 023608102   17,585 235 SH   SOLE   235 0 0
ANALOG DEVICES INC COM 032654105   1,172,753 6,698 SH   SOLE   6,698 0 0
APOGEE THERAPEUTICS INC COM 03770N101   6,042,448 283,683 SH   SOLE   283,683 0 0
APPLIED MATLS INC COM 038222105   2,056,675 14,855 SH   SOLE   14,855 0 0
APTIV PLC SHS G6095L109   155,476 1,577 SH   SOLE   1,577 0 0
ARCUS BIOSCIENCES INC COM 03969F109   3,668,944 204,398 SH   SOLE   204,398 0 0
ARDAGH METAL PACKAGING S A SHS L02235106   84,911 27,128 SH   SOLE   27,128 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   2,610,904 97,168 SH   SOLE   97,168 0 0
AT&T INC COM 00206R102   101,175 6,736 SH   SOLE   6,736 0 0
AUTOLIV INC COM 052800109   175,208 1,816 SH   SOLE   1,816 0 0
BALL CORP COM 058498106   249,000 5,002 SH   SOLE   5,002 0 0
BAXTER INTL INC COM 071813109   55,137,083 1,460,972 SH   SOLE   1,324,111 0 136,861
BEST BUY INC COM 086516101   96,355 1,387 SH   SOLE   1,387 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   5,735,273 285,479 SH   SOLE   285,479 0 0
BIO RAD LABS INC CL A 090572207   3,095,574 8,636 SH   SOLE   8,636 0 0
BIOGEN INC COM 09062X103   6,179,548 24,044 SH   SOLE   24,044 0 0
BIONTECH SE SPONSORED ADS 09075V102   7,424,240 68,338 SH   SOLE   68,338 0 0
BLOCK INC CL A 852234103   11,573,592 261,491 SH   SOLE   261,491 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   252,004 5,018 SH   SOLE   5,018 0 0
BOOKING HOLDINGS INC COM 09857L108   12,224,778 3,964 SH   SOLE   3,964 0 0
CADENCE DESIGN SYSTEM INC COM 127387108   56,466 241 SH   SOLE   241 0 0
CALIFORNIA RES CORP COM STOCK 13057Q305   96,785 1,728 SH   SOLE   1,728 0 0
CAMECO CORP COM 13321L108   122,605,316 3,089,235 SH   SOLE   2,787,533 0 301,702
CARLISLE COS INC COM 142339100   83,868,017 323,490 SH   SOLE   294,537 0 28,953
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   2,183,910 337,544 SH   SOLE   337,544 0 0
CENTOGENE N V COM N1976T109   2,519,779 2,377,150 SH   SOLE   2,377,150 0 0
CF INDS HLDGS INC COM 125269100   133,926 1,562 SH   SOLE   1,562 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108   141,622 322 SH   SOLE   322 0 0
CHEWY INC CL A 16679L109   1,230,395 67,382 SH   SOLE   67,382 0 0
CIENA CORP COM NEW 171779309   1,614,969 34,172 SH   SOLE   34,172 0 0
CISCO SYS INC COM 17275R102   453,466 8,435 SH   SOLE   8,435 0 0
CMS ENERGY CORP COM 125896100   18,482 348 SH   SOLE   348 0 0
COGENT BIOSCIENCES INC COM 19240Q201   4,639,411 475,837 SH   SOLE   451,004 0 24,833
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102   95,039 1,403 SH   SOLE   1,403 0 0
CORE LABORATORIES INC COM 21867A105   93,135 3,879 SH   SOLE   3,879 0 0
CROWN HLDGS INC COM 228368106   287,648 3,251 SH   SOLE   3,251 0 0
CUREVAC N V COM N2451R105   2,481,202 363,280 SH   SOLE   363,280 0 0
DINGDONG CAYMAN LTD ADS 25445D101   17,827,308 9,142,209 SH   SOLE   9,142,209 0 0
DOLBY LABORATORIES INC COM CL A 25659T107   108,665 1,371 SH   SOLE   1,371 0 0
DOORDASH INC CL A 25809K105   15,643,670 196,850 SH   SOLE   196,850 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204   20,035 227 SH   SOLE   227 0 0
ERICSSON ADR B SEK 10 294821608   1,570,631 323,175 SH   SOLE   323,175 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105   3,125,727 3,189,517 SH   SOLE   2,919,201 0 270,316
EXSCIENTIA PLC ADS 30223G102   19,865,662 4,395,058 SH   SOLE   4,358,901 0 36,157
FORTINET INC COM 34959E109   52,812 900 SH   SOLE   900 0 0
FOX CORP CL A COM 35137L105   48,079 1,541 SH   SOLE   1,541 0 0
FREEPORT-MCMORAN INC CL B 35671D857   7,401,245 198,478 SH   SOLE   198,478 0 0
GOSSAMER BIO INC COM 38341P102   4,461,958 5,357,778 SH   SOLE   5,357,778 0 0
H WORLD GROUP LTD SPONSORED ADS 44332N106   13,612,577 345,234 SH   SOLE   345,234 0 0
HANESBRANDS INC COM 410345102   86,989 21,967 SH   SOLE   21,967 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104   43,093 1,315 SH   SOLE   1,315 0 0
HELLO GROUP INC ADS 423403104   29,812 4,271 SH   SOLE   4,271 0 0
HERBALIFE LTD COM SHS G4412G101   94,726 6,771 SH   SOLE   6,771 0 0
HUTCHMED CHINA LTD SPONSORED ADS 44842L103   3,083,961 182,052 SH   SOLE   182,052 0 0
ICOSAVAX INC COM 45114M109   18,103,938 2,335,992 SH   SOLE   2,181,462 0 154,530
IDEAYA BIOSCIENCES INC COM 45166A102   20,685,080 766,682 SH   SOLE   661,747 0 104,935
IMMATICS N.V SHS N44445109   3,105,883 268,211 SH   SOLE   268,211 0 0
IMMUNOVANT INC COM 45258J102   8,673,798 225,939 SH   SOLE   225,939 0 0
INHIBRX INC COM 45720L107   4,202,811 229,036 SH   SOLE   229,036 0 0
INTEL CORP COM 458140100   275,050 7,737 SH   SOLE   7,737 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104   137,679,688 1,251,406 SH   SOLE   973,577 0 277,829
IRIS ENERGY LTD ORDINARY SHARES Q4982L109   9,672,237 2,607,072 SH   SOLE   2,241,944 0 365,128
JACKSON FINANCIAL INC COM CL A 46817M107   96,888 2,535 SH   SOLE   2,535 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   90,220 697 SH   SOLE   697 0 0
JD.COM INC SPON ADR CL A 47215P106   15,944,102 547,343 SH   SOLE   547,343 0 0
JOHNSON & JOHNSON COM 478160104   6,642,270 42,647 SH   SOLE   42,647 0 0
KOHLS CORP COM 500255104   95,787 4,570 SH   SOLE   4,570 0 0
KYNDRYL HLDGS INC COMMON STOCK 50155Q100   3,639 241 SH   SOLE   241 0 0
LAM RESEARCH CORP COM 512807108   8,216,955 13,110 SH   SOLE   13,110 0 0
LIBERTY MEDIA CORP DEL COM LBTY ONE S C 531229755   953,190 15,300 SH   SOLE   15,300 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102   19,237 18,148 SH   SOLE   18,148 0 0
MATCH GROUP INC NEW COM 57667L107   3,124,598 79,760 SH   SOLE   79,760 0 0
MERUS N V COM N5749R100   3,349,044 142,029 SH   SOLE   142,029 0 0
META PLATFORMS INC CL A 30303M102   55,314,893 184,254 SH   SOLE   184,254 0 0
METALS ACQUISITION LIMITED ORD SHS G60409110   24,395,449 2,036,348 SH   SOLE   1,520,073 0 516,275
MICROCHIP TECHNOLOGY INC. COM 595017104   231,567,091 2,966,907 SH   SOLE   2,568,313 0 398,594
MICRON TECHNOLOGY INC COM 595112103   107,949,664 1,586,795 SH   SOLE   1,314,146 0 272,649
MICROSOFT CORP COM 594918104   6,547,392 20,736 SH   SOLE   20,736 0 0
MOBILEYE GLOBAL INC COMMON CLASS A 60741F104   41,501,262 998,827 SH   SOLE   693,661 0 305,166
MODERNA INC COM 60770K107   8,401,195 81,336 SH   SOLE   81,336 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109   3,930,436 2,285,137 SH   SOLE   2,254,018 0 31,119
NETFLIX INC COM 64110L106   2,710,790 7,179 SH   SOLE   7,179 0 0
NEW YORK CMNTY BANCORP INC COM 649445103   86,785 7,653 SH   SOLE   7,653 0 0
NOAH HLDGS LTD SPON ADS CL A 65487X102   32,209,050 2,582,923 SH   SOLE   2,582,923 0 0
NOBLE CORP PLC ORD SHS A G65431127   91,373 1,804 SH   SOLE   1,804 0 0
NUTRIEN LTD COM 67077M108   128,770 2,085 SH   SOLE   2,085 0 0
NVIDIA CORPORATION COM 67066G104   262,299 603 SH   SOLE   603 0 0
NXP SEMICONDUCTORS N V COM N6596X109   62,054,168 310,395 SH   SOLE   266,667 0 43,728
OMEGA THERAPEUTICS INC COMMON STOCK 68217N105   1,907,087 887,017 SH   SOLE   860,216 0 26,801
ONEMAIN HLDGS INC COM 68268W103   96,457 2,406 SH   SOLE   2,406 0 0
ORACLE CORP COM 68389X105   2,557,227 24,143 SH   SOLE   24,143 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200   1,920,611 248,462 SH   SOLE   248,462 0 0
PAYPAL HLDGS INC COM 70450Y103   477,092 8,161 SH   SOLE   8,161 0 0
PDD HOLDINGS INC SPONSORED ADS 722304102   145,277,956 1,481,370 SH   SOLE   1,247,054 0 234,316
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408   52,001,149 3,469,056 SH   SOLE   2,389,758 0 1,079,298
PLANET FITNESS INC CL A 72703H101   8,246,748 167,685 SH   SOLE   167,685 0 0
PROTHENA CORP PLC SHS G72800108   2,002,761 41,508 SH   SOLE   41,508 0 0
QUANTERIX CORP COM 74766Q101   17,897,962 659,468 SH   SOLE   613,495 0 45,973
RALPH LAUREN CORP CL A 751212101   99,141 854 SH   SOLE   854 0 0
RAYZEBIO INC COM 75525N107   4,933,328 222,222 SH   SOLE   222,222 0 0
RECURSION PHARMACEUTICALS IN CL A 75629V104   17,863,760 2,335,132 SH   SOLE   2,289,838 0 45,294
RH COM 74967X103   25,213,335 95,375 SH   SOLE   89,043 0 6,332
ROIVANT SCIENCES LTD SHS G76279101   6,993,190 598,732 SH   SOLE   598,732 0 0
RYANAIR HOLDINGS PLC SPONSORED ADS 783513203   972,100 10,000 SH   SOLE   10,000 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   3,378,434 383,913 SH   SOLE   383,913 0 0
SAREPTA THERAPEUTICS INC COM 803607100   1,245,536 10,275 SH   SOLE   10,275 0 0
SCHLUMBERGER LTD COM STK 806857108   112,180,510 1,924,194 SH   SOLE   1,654,895 0 269,299
SCHWAB CHARLES CORP COM 808513105   1,372,500 25,000 SH   SOLE   25,000 0 0
SCORPIO TANKERS INC SHS Y7542C130   24,455,313 451,872 SH   SOLE   451,872 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100   162,856 427,444 SH   SOLE   427,444 0 0
SKYWORKS SOLUTIONS INC COM 83088M102   98,097 995 SH   SOLE   995 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   2,645,084 52,461 SH   SOLE   52,461 0 0
SUZANO S A SPON ADS 86959K105   49,663,839 4,619,892 SH   SOLE   4,619,892 0 0
THE CIGNA GROUP COM 125523100   97,836 342 SH   SOLE   342 0 0
THOR INDS INC COM 885160101   98,079 1,031 SH   SOLE   1,031 0 0
TORM PLC SHS CL A G89479102   2,196,784 79,825 SH   SOLE   79,825 0 0
TRANSUNION COM 89400J107   115,790,665 1,612,908 SH   SOLE   1,401,112 0 211,796
TRIP COM GROUP LTD ADS 89677Q107   117,831,240 3,369,495 SH   SOLE   2,975,041 0 394,454
TWILIO INC CL A 90138F102   289,314 4,943 SH   SOLE   4,943 0 0
TYSON FOODS INC CL A 902494103   88,105 1,745 SH   SOLE   1,745 0 0
UNIVERSAL HLTH SVCS INC CL B 913903100   91,406 727 SH   SOLE   727 0 0
V F CORP COM 918204108   99,889 5,653 SH   SOLE   5,653 0 0
VALARIS LTD CL A G9460G101   74,296,857 990,889 SH   SOLE   808,610 0 182,279
VEEVA SYS INC CL A COM 922475108   714,516 3,512 SH   SOLE   3,512 0 0
VERA THERAPEUTICS INC CL A 92337R101   2,746,140 200,302 SH   SOLE   200,302 0 0
VITAL ENERGY INC COM 516806205   47,495 857 SH   SOLE   857 0 0
WARNER BROS DISCOVERY INC COM SER A 934423104   45,623 4,201 SH   SOLE   4,201 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   2,618,153 455,331 SH   SOLE   455,331 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105   345,987,483 14,314,749 SH   SOLE   12,446,037 0 1,868,712
ZYMEWORKS INC COM 98985Y108   2,598,379 409,839 SH   SOLE   409,839 0 0