10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 10-Q

xQUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended June 30, 2014

OR

oTRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from                  to                 

Commission File Number: 001-35706

LPATH, INC.

(Exact name of registrant as specified in its charter)

Delaware	16-1630142
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)

4025 Sorrento Valley Blvd., San Diego, CA 92121

(Address of principal executive offices, including zip code)

(858) 678-0800

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.  Yes x No o

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).  Yes x No o

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definitions of “large accelerated filer,” “accelerated filer,” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer o	Accelerated filer o
Non-accelerated filer o	Smaller reporting company x
(Do not check if a smaller reporting company)

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).  Yes o No x

The number of shares of issuer’s outstanding Class A common stock as of August 8, 2014 was 15,618,666.

LPATH, INC.

FORM 10-Q

June 30, 2014

TABLE OF CONTENTS

PART I	FINANCIAL INFORMATION	4
ITEM 1:	Financial Statements	4
ITEM 2:	Management’s Discussion and Analysis of Financial Condition and Results of Operations	10
ITEM 4:	Controls and Procedures	13
PART II	OTHER INFORMATION	14
ITEM 1:	Legal Proceedings	14
ITEM 1A:	Risk Factors	14
ITEM 2:	Unregistered Sales of Equity Securities and Use of Proceeds	15
ITEM 3:	Defaults upon Senior Securities	15
ITEM 4:	Mine Safety Disclosure	15
ITEM 5:	Other Information	15
ITEM 6:	Exhibits	16
SIGNATURES		19

2

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS

This report includes statements of our expectations, intentions, plans, and beliefs that constitute “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and are intended to come within the safe harbor protection provided by those sections. These forward-looking statements are principally, but not solely, contained in the section captioned “Management’s Discussion and Analysis of Financial Condition and Results of Operations.” Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate or imply future results, performance or achievements, and may contain the words “estimate,” “project,” “intend,” “forecast,” “anticipate,” “plan,” “planning,” “expect,” “believe,” “will,” “will likely,” “should,” “could,” “would,” “may” or words or expressions of similar meaning.  The matters discussed in these forward-looking statements are subject to risks, uncertainties and other factors that could cause our actual results to differ materially from those projected, anticipated or implied in the forward-looking statements. Many of these risks, uncertainties and other factors are beyond our ability to control or predict. The most significant of these risks, uncertainties and other factors are described in “Item 1A—Risk Factors” of this Quarterly Report on Form 10-Q and our Annual Report on Form 10-K for the fiscal year ended December 31, 2013 filed with the Securities and Exchange Commission on March 18, 2014. These forward-looking statements reflect our views and assumptions only as of the date such forward-looking statements are made. Except to the limited extent required by applicable law, we undertake no obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

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PART I. FINANCIAL INFORMATION

Item 1. FINANCIAL STATEMENTS

LPATH, INC.

Condensed Consolidated Balance Sheets

(Unaudited)

	June 30,			December 31,
	2014			2013
ASSETS
Current Assets:
Cash and cash equivalents	$	14,263,475		$	11,851,639
Accounts receivable	1,313,503			1,310,037
Prepaid expenses and other current assets	417,988			292,477
Total current assets	15,994,966			13,454,153
Equipment and leasehold improvements, net	260,924			211,362
Patents, net	2,074,192			1,926,868
Deposits and other assets	77,350			77,350
Total assets	$	18,407,432		$	15,669,733
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current Liabilities:
Accounts payable	$	2,544,122		$	2,025,799
Accrued compensation	416,991			693,022
Accrued expenses	270,347			291,358
Deferred contract revenue, current portion	250,000			498,000
Deferred rent, short-term portion	28,804			24,008
Total current liabilities	3,510,264			3,532,187
Deferred rent, long-term portion	54,971			69,373
Warrants	1,700,000			2,100,000
Total liabilities	5,265,235			5,701,560
Stockholders’ Equity:
Common stock - $.001 par value; 100,000,000 shares authorized; 15,591,161 and 13,387,914 issued and outstanding at June 30, 2014 and December 31, 2013, respectively	15,591			13,388
Additional paid-in capital	69,631,214			59,432,943
Accumulated deficit	(56,504,608		)	(49,478,158		)
Total stockholders’ equity	13,142,197			9,968,173
Total liabilities and stockholders’ equity	$	18,407,432		$	15,669,733

See accompanying notes to the condensed consolidated financial statements.

4

LPATH, INC.

Condensed Consolidated Statements of Operations

(Unaudited)

	Six Months Ended June 30,						Three Months Ended June 30,
	2014			2013			2014			2013
Revenues:
Grant and royalty revenue	$	316,083		$	577,295		$	199,984		$	353,075
Research and development revenue under collaborative agreements	2,735,386			2,551,111			1,132,109			1,663,521
Total revenues	3,051,469			3,128,406			1,332,093			2,016,596
Expenses:
Research and development	8,237,972			4,424,161			4,574,964			2,839,477
General and administrative	2,239,965			2,112,742			1,083,008			1,108,887
Total expenses	10,477,937			6,536,903			5,657,972			3,948,364
Loss from operations	(7,426,468		)	(3,408,497		)	(4,325,879		)	(1,931,768		)
Other income, net	18			27,022			18			—
Change in fair value of warrants	400,000			750,000			600,000			550,000
Total other income (expense), net	400,018			777,022			600,018			550,000
Net loss	$	(7,026,450	)	$	(2,631,475	)	$	(3,725,861	)	$	(1,381,768	)
Basic and diluted net loss per share	$	(0.46	)	$	(0.20	)	$	(0.23	)	$	(0.10	)
Weighted-average shares outstanding used in the calculation	15,192,395			13,410,696			15,865,634			13,419,512

See accompanying notes to the condensed consolidated financial statements.

5

LPATH, INC.

Condensed Consolidated Statements of Cash Flows

Six Months Ended June 30,

(Unaudited)

	2014			2013
Cash flows from operating activities:
Net loss	$	(7,026,450	)	$	(2,631,475	)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	704,226			402,759
Change in fair value of warrants	(400,000		)	(750,000		)
Depreciation and amortization	98,948			129,047
Changes in operating assets and liabilities:
Accounts receivable	(3,466		)	(148,490		)
Prepaid expenses and other current assets	(125,511		)	113,379
Accounts payable and accrued expenses	195,364			(1,437,809		)
Deferred contract revenue	(248,000		)	(2,491,016		)
Other	(9,606		)	(36,919		)
Net cash used in operating activities	(6,814,495		)	(6,850,524		)
Cash flows from investing activities:
Equipment and leasehold improvement expenditures	(99,007		)	(37,734		)
Patent expenditures	(196,827		)	(185,564		)
Net cash used in investing activities	(295,834		)	(223,298		)
Cash flows from financing activities:
Proceeds from sale of common stock and warrants, net	9,604,892			—
Proceeds from options and warrants exercised	250			3,289
Payment for restricted stock tax liability on net settlement	(82,977		)	(44,833		)
Net cash provided by(used in) financing activities	9,522,165			(41,544		)
Net (decrease) increase in cash and cash equivalents	2,411,836			(7,115,366		)
Cash and cash equivalents at beginning of period	11,851,639			24,621,083
Cash and cash equivalents at end of period	$	14,263,475		$	17,505,717
Supplemental disclosure of cash flow information:
Cash paid during the year for:
Income taxes	$	1,600		$	1,600
Supplemental disclosure of non-cash investing and financing activities:
Change in fair value of warrant liability	$	(400,000	)	$	(750,000	)

See accompanying notes to the condensed consolidated financial statements.

6

LPATH, INC.

Notes to Condensed Consolidated Financial Statements

June 30, 2014

Note 1 — BASIS FOR PRESENTATION

The unaudited condensed consolidated balance sheet of Lpath, Inc. (“Lpath” or “the company”) as of December 31, 2013 was derived from our audited financial statements, but does not contain all disclosures required by accounting principles generally accepted in the United States of America, and certain information and disclosures normally included have been condensed or omitted pursuant to the rules and regulations of the SEC.

In the opinion of management, all adjustments considered necessary for a fair presentation have been included. Except as otherwise disclosed, all such adjustments are of a normal recurring nature. Operating results for the three-month and six-month periods ended June 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014 or for any future financial period. For further information, refer to the consolidated financial statements and notes included in the company’s annual report on Form 10-K for the year ended December 31, 2013.

The preparation of the consolidated financial statements in conformity with U.S. generally accepted accounting principles (“GAAP”) requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

Recent Accounting Pronouncements

In May 2014, the FASB issued ASU No. 2014-09, Revenue from Contracts with Customers, a converged standard on revenue recognition. The new pronouncement requires revenue recognition to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The guidance also specifies the accounting for some costs to obtain or fulfil a contract with a customer, as well as enhanced disclosure requirements.  ASU 2014-9 is effective for annual reporting periods beginning after December 15, 2016. Early adoption is not permitted. The adoption of ASC 2014-9 is not expected to have a material effect on our consolidated financial statements.

Note 2 — RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

In 2010, Lpath entered into an agreement providing Pfizer Inc. (“Pfizer”) with an exclusive option for a worldwide license to develop and commercialize iSONEP™ (“the Pfizer Agreement”), Lpath’s lead monoclonal antibody product candidate that is being evaluated for the treatment of wet age-related macular degeneration (“wet AMD”) and other ocular disorders.

Following completion of the clinical trial, Pfizer has the right to exercise its option for worldwide rights to iSONEP for an undisclosed option fee and, if Pfizer exercises its option, Lpath will be eligible to receive development, regulatory, and commercial milestone payments that could total up to $497.5 million.  In addition, Lpath will be entitled to receive tiered double-digit royalties based on sales of iSONEP. As part of the agreement, Lpath has granted to Pfizer a time-limited right of first refusal for ASONEP™, Lpath’s product candidate that is being evaluated for the treatment of cancer.

The company recognized revenue under research and development collaborative agreements as follows:

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Cost reimbursements	$	2,487,386	$	—	$	1,008,109	$	—
Amortization of license and development fees	248,000		2,491,015		124,000		1,603,425
Other	—		60,096		—		60,096
	$	2,735,386	$	2,551,111	$	1,132,109	$	1,663,521

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Note 3 — SHARE-BASED PAYMENTS

The company recognized share-based compensation expense as follows:

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Research and development	$	232,913	$	122,849	$	118,261	$	82,439
General and administrative	471,313		279,910		268,164		126,434
Total share-based compensation expense	$	704,226	$	402,759	$	386,425	$	208,873

As of June 30, 2014, there was a total of $2.4 million in unrecognized compensation expense related to unvested stock-based compensation under the Lpath, Inc. Amended and Restated 2005 Equity Incentive Plan. That expense is expected to be recognized over a weighted-average period of 2.5 years. Because of its net operating loss carryforwards, the company did not realize any tax benefits for the tax deductions from share-based payment arrangements during the three-month periods ended June 30, 2014 and 2013.

Note 4 — FAIR VALUE MEASUREMENTS

Lpath has issued warrants, of which some are classified as equity and some as liabilities.  The warrants issued in March 2012 (and expiring in March 2017) provide that in the event of a fundamental transaction, as defined by the warrant agreement, the company may, under certain circumstances, be obligated to settle the March 2012 warrants for cash equal to the value of the warrants determined in accordance with the warrant agreement.  The company’s recurring fair value measurements at June 30, 2014 were as follows:

	Fair Value as of June 30, 2014		Significant Unobservable Inputs (Level 3)
Liabilities:
Warrants expiring March 2017	$	1,700,000	$	1,700,000

The company determined the fair value of the warrant liability for certain warrants, as applicable, using a Black-Scholes model. The model considered amounts and timing of future possible equity and warrant issuances and volatility of the company’s stock price equal to 100%, as specified in the underlying warrants.

Recurring Level 3 Activity, Reconciliation, and Basis for Valuation

The table below provides a reconciliation of the beginning and ending balances for the liabilities measured at fair value using significant unobservable inputs (Level 3).

Fair value measurements using significant unobservable inputs (Level 3):

Liabilities:
Warrant liability as of January 1, 2014	$	2,100,000
Change in fair value of warrants	(400,000		)
Warrant liability as of June 30, 2014	$	1,700,000

The company determined the fair value of the warrant liability for certain warrants, as applicable, using a Black-Scholes model. The model considered amounts and timing of future possible equity and warrant issuances and historical volatility of the company’s stock price.

The terms of all outstanding warrants permit the company, upon exercise of the warrants, to settle the contract by the delivery of unregistered shares. During the three months ended June 30, 2014, 5,715 warrants expired.  As of June 30, 2014, there were 924,241 warrants outstanding with a weighted-average exercise price of $7.58 per share expiring through May 2017.

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Note 5 — COMMON STOCK

On March 18, 2014, Lpath entered into an at-the-market issuance sales agreement with MLV (the “MLV Agreement”). Pursuant to the MLV Agreement, the company may issue and sell shares of its common stock having an aggregate offering price of up to $23 million (subject to limitations set by the SEC if the aggregate market-value of the company’s common stock held by non-affiliates remains below $75 million) from time to time, at the company’s option, through MLV. Sales of common stock through MLV, if any, will be made by any method that is deemed an “at-the-market” offering as defined in Rule 415 promulgated under the Securities Act of 1933, as amended, including by means of ordinary brokers’ transactions at market prices, in block transactions or as otherwise agreed by the Lpath and MLV. Subject to the terms and conditions of the MLV Agreement, MLV will use commercially reasonable efforts to sell the common stock based upon the company’s instructions (including any price, time or size limits or other customary parameters or conditions the Company may impose). Lpath is not obligated to make any sales of its common stock under the MLV Agreement. Any shares sold will be sold pursuant to the company’s effective shelf registration statement on Form S-3. The company will pay MLV a commission of up to 3.0% of the gross proceeds. The MLV Agreement will terminate upon the earlier of the sale of all common stock subject to the MLV Agreement or termination of the MLV Agreement by the company or MLV. During the quarter ended June 30, 2014, the company sold 268,840 shares at sales prices ranging from $4.25 to $4.76 per share, resulting in $1,189,000 in net proceeds. From July 1, 2014 to August 8, 2014, the company sold 27,505 shares at sales prices ranging from $3.50 to $4.08 per share, resulting in $99,000 in net proceeds.

Note 6 — EARNINGS PER SHARE

Anti-dilutive common stock equivalents were excluded from the calculation of diluted loss per share as follows:

	Six and Three Months Ended
	June 30,
Stock options	802,829	362,469
Warrants	924,241	1,261,874
Restricted stock units	636,209	713,989
Total	2,363,279	2,338,332

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Item 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

This discussion and analysis of the financial condition and results of operations of Lpath, Inc. (“Lpath”, the “company”, “we”, “us”, or “our”) should be read in conjunction with our condensed consolidated financial statements and notes thereto included in this Quarterly Report on Form 10-Q and the audited financial statements and notes thereto included in our Annual Report on Form 10-K for the year ended December 31, 2013, as filed with the Securities and Exchange Commission (the “SEC”). In addition to historical information, this discussion and analysis contains forward-looking statements that involve risks, uncertainties, and assumptions. Our actual results may differ materially from those anticipated in these forward-looking statements as a result of certain factors including, but not limited to, those identified in “Item 1A—Risk Factors” of this Quarterly Report on Form 10-Q and our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

Overview

We are a biotechnology company focused on the discovery and development of lipidomic-based therapeutic antibodies, an emerging field of medical science that targets bioactive signaling lipids to treat a wide range of human diseases. We have two product candidates that are currently in clinical development, and one in pre-clinical evaluation.

iSONEP™ is the ocular formulation of sonepcizumab, a humanized monoclonal antibody (“mAb”) against sphingosine-1-phosphate (“S1P”). Sphingomab™ is the original mouse version of this monoclonal antibody. iSONEP is administered by intravitreal injection, and has demonstrated multiple mechanisms of action in ocular models of disease, including anti-angiogenesis, anti-inflammatory, anti-fibrotic and anti-vascular permeability. This combination of mechanisms would suggest: (i) iSONEP might have a comparative advantage over currently marketed products for “wet” age-related macular degeneration (“wet AMD”) and (ii) iSONEP might demonstrate clinical efficacy in a broad range of retinal diseases where there is currently a significant unmet medical need, including diabetic retinopathy, dry AMD, and glaucoma-related surgery.

We entered into an agreement with Pfizer Inc. in December 2010, and amended it in 2012 (collectively, the “Pfizer Agreement”), that provides Pfizer with an exclusive option for a worldwide license to develop and commercialize iSONEP.  Under the Pfizer Agreement, we are conducting a Phase 2 study in wet AMD patients (the “Nexus trial”).  We began enrolling patients in the Nexus trial in October 2011.  We anticipate to complete dosing the last Nexus trial patient during the second half of 2014. The actual time required to complete our clinical trials will depend upon a number of factors outside of our direct control, including those discussed in “Risk Factors — We may have delays in completing our clinical trials, and we may not complete them at all” in our Form 10-K for the fiscal year ended December 31, 2013.

In October 2013, we announced that we had received notice from Pfizer that Pfizer would be seeking to divest certain ophthalmology research and development assets, including Pfizer’s rights and obligations under the Pfizer Agreement.  We presented offers to Pfizer to reacquire those rights. However, in December 2013, Pfizer informed us that our offers were not competitive with other offers. Acquisition of Pfizer’s rights and obligations under the terms of the Pfizer Agreement by a third party would not affect the terms of the Pfizer Agreement, as the existing rights and obligations currently held by Pfizer will be assumed by to the third party or remain with Pfizer based on the terms of the agreement between Pfizer and the third party.  Since December 2013, Pfizer has maintained its position that it is continuing a process to divest certain of its ophthalmology research and development assets, including its rights and obligations under the Pfizer Agreement.  Nevertheless, we believe that Pfizer may now be waiting until they receive the results of the Nexus trial before completing or stopping its process, given that we are closer to the completion of the Nexus trial.

Following completion of the Nexus study, Pfizer (or a third party who may acquire Pfizer’s rights) has the right to exercise its option for worldwide rights to iSONEP for an undisclosed option fee and, if Pfizer (or a third party who may acquire Pfizer’s rights) exercises its option, we will be eligible to receive development, regulatory, and commercial milestone payments that could total up to $497.5 million. In addition, we will be entitled to receive tiered double-digit royalties based on sales of iSONEP.

As of June 30, 2014, Pfizer had paid the Company $22.6 million pursuant to the terms of the Pfizer Agreement. The amendment to the Pfizer Agreement did not modify the Company’s obligation to fund $6.0 million of Nexus trial expenses, which it completed during 2013. The terms of the Pfizer Agreement specify that, since the Company has fulfilled its funding obligation, Pfizer (or any third party who acquires Pfizer’s rights) will fund the remaining expenses necessary to complete the Nexus trial. Pfizer has continued to meet its funding obligations under the Pfizer Agreement.

ASONEP™ is the systemic formulation of sonepcizumab.  We are collaborating with investigators at several medical research institutions on a Phase 2 clinical trial testing ASONEP as a treatment for renal cell carcinoma. In July 2014, we reported interim results for this study, and announced that, based on the safety profile of ASONEP and promising interim results, we plan to move the project forward and initiate dosing in a second cohort of patients.

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As part of the Pfizer Agreement, Lpath has granted to Pfizer (or a third party who may acquire Pfizer’s rights) a time-limited right of first refusal for ASONEP, which period ends on the latest date that Pfizer, or a third party who may acquire Pfizer’s rights, may exercise its option to continue development of iSONEP.

Lpathomab™, our pre-clinical product candidate, is a mAb against lysophosphatidic acid (“LPA”), a key bioactive lipid that has long been recognized as a significant promoter of cancer-cell growth and metastasis in a broad range of tumor types. Published research has also demonstrated that LPA is a significant contributor to neuropathic pain and traumatic brain injury, and plays a key role in pulmonary fibrosis. We have selected the clinical candidate mAb from among three humanized mAbs that inhibit LPA. These mAbs were tested against each other in various models of human disease to determine which mAb would be most likely to succeed in clinical trials. We are now engaged in the antibody manufacturing process development activities and expect to complete Investigational New Drug (“IND”) enabling studies in 2014. We plan to file the IND in early 2015, and begin testing Lpathomab in clinical trials thereafter.

Lpath has incurred significant net losses since its inception. As of June 30, 2014, we had an accumulated deficit of approximately $56.5 million. We expect that the cost of our ongoing research and development activities, including general and administrative expenses, will approximate $22 million from July 1, 2014 through the June 30, 2015. This estimate includes the expenses to conduct the Nexus clinical trial for iSONEP, as well as the Phase 2 clinical trial for ASONEP. In addition, this estimate includes the expenses to complete the manufacturing of the Lpathomab clinical drug product and conduct the IND-enabling studies for Lpathomab. As of June 30, 2014, we had cash and cash equivalents totaling $14.3 million. Additional near-term sources of cash include our accounts receivable of $1.3 million, as well as additional funding pursuant to the terms of the Pfizer Agreement to support our Nexus clinical trial. We also have $0.3 million of unexpended funding remaining on NIH grants awarded to the company. We believe these funds should be sufficient to fund our planned drug discovery and development activities through the second quarter of 2015. However, the continuation of our current clinical development activities beyond the second quarter of 2015 is dependent upon our ability to obtain additional funding. In the event that we are unable to obtain additional funding, certain planned research and development activities will be deferred or curtailed. Even if we reduce our research and development expenses, the continuation of our operations subsequent to the second quarter of 2015 is dependent on our ability to obtain significant additional funding.

We expect our expenditures to increase as we continue the advancement of our product development programs. The lengthy process of completing clinical trials and seeking regulatory approval for one product candidate typically requires expenditures in excess of approximately $100 million, according to industry data. Any failure by us or delay in completing clinical trials, or in obtaining regulatory approvals, would cause our research and development expenses to increase and, in turn, have a material adverse effect on our results of operations.

Results of Operations

Grant and Royalty Revenue.  Grant and royalty revenues for the quarter ended June 30, 2014 were $200,000 compared to $353,000 for the quarter ended June 30, 2013. For the first half of 2014. Grant and royalty revenues were $316,000 compared to $577,000 for the first half of 2013, a decrease of $261,000.  The decreases in 2014 were due to the completion of one of our NIH grants in August 2013.

Research and Development Revenue Under Collaborative Agreement.  As described in Note 2 to the condensed consolidated financial statements, in December 2010 we entered into an agreement with Pfizer that provides financial support for our iSONEP and ASONEP development programs. We recognized revenues under research and development collaborative agreements as follows:

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Cost reimbursements	$	2,487,386	$	—	$	1,008,109	$	—
Amortization of license and development fees	248,000		2,491,015		124,000		1,603,425
Other	—		60,096		—		60,096
	$	2,735,386	$	2,551,111	$	1,132,109	$	1,663,521

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During the fourth quarter of 2013, we reached the point in the contract where Pfizer became responsible for funding the iSONEP development costs pursuant to the terms of the Pfizer Agreement.  During the first half of 2013, Lpath was responsible for funding iSONEP development costs, resulting in increased amortization of development fees in 2013 compared to 2014.

Research and Development Expenses.  Research and development expenses increased to $8,238,000 for the first half of 2014 from $4,424,000 for the first half of 2013, an increase of $3,814,000.  For the second quarter of 2014, research and development expenses increased to $4,575,000 from $2,839,000 for the second quarter of 2013, an increase of $1,736,000.  The increases in 2014 were driven by the increased costs of our ongoing clinical trials, especially the expenses related to manufacturing process development and scale-up and IND-enabling studies for the Lpathomab program, as well as the addition of new employees in the research and development functions.

General and Administrative Expenses. General and administrative expenses were $2,240,000 for the six-month period ended June 30, 2014 compared to $2,112,000 for the same period in 2013, an increase of $128,000.  This increase is principally attributable to increased stock compensation expense incurred in connection with options issued to employees in 2014.

General and administrative expenses were $1,083,000 for the quarter ended June 30, 2014 compared to $1,109,000 for the same period in 2013, a decrease of $26,000.  This decrease is principally attributable to reduced legal fees in 2014.

Change in Fair Value of Warrants. Various factors are considered in the pricing model we use to value outstanding warrants, including the company’s current stock price, the remaining life of the warrants, and the risk-free interest rate. Future changes in these factors will have a significant impact on the computed fair value of the warrant liability. The most significant factor in the valuation model is the company’s stock price. Lpath’s stock is thinly traded and relatively small transactions can impact the company’s quoted stock price significantly.  As such, we expect future changes in the fair value of the warrants to continue to vary significantly from quarter to quarter. Management cautions that the net change in fair value of the warrants reflected in the statement of operations, and all similar changes in the future, should not be given undue importance when considering the financial condition of Lpath and the results of its operations. Management does not believe that these adjustments, which are required by current generally accepted accounting principles, reflect economic activities or financial obligations undertaken by the company.

Liquidity and Capital Resources

As of June 30, 2014, Lpath had cash and cash equivalents totaling $14.3 million. Additional near-term sources of cash include our accounts receivable of $1.3 million as well as additional funding pursuant to the terms of the Pfizer Agreement to support our Nexus clinical trial. We also have $0.3 million of unexpended funding remaining on NIH grants awarded to the company. We expect that the cost of our ongoing research and development activities, including general and administrative expenses, will approximate $22 million from July 1, 2014 through the June 30, 2015.  This estimate includes the expenses to conduct the Nexus clinical trial for iSONEP, as well as the Phase 2 clinical trial for ASONEP. In addition, this estimate includes the expenses to complete the manufacturing of the Lpathomab clinical drug product and conduct the IND-enabling studies for Lpathomab. We believe our cash on hand as of June 30, 2014, together with amounts to be received pursuant to the Pfizer Agreement and NIH grants, should be sufficient to fund our ongoing research and development activities, as currently planned, through the second quarter of 2015. However, the continuation of our current clinical development activities beyond the second quarter of 2015 is dependent upon our ability to obtain additional funding. In the event that we are unable to obtain additional funding, certain planned research and development activities will be deferred or curtailed. Even if we reduce our research and development expenses, the continuation of our operations subsequent to the second quarter of 2015 is dependent on our ability to obtain significant additional funding.

We may receive additional funding to support our operations beyond the second quarter of 2015 under the terms of the Pfizer Agreement if Pfizer (or any third party who may acquire Pfizer’s rights) elects to exercise its option to continue the clinical development of iSONEP. However, we cannot assure you that we will be successful in maintaining our commercial relationship with Pfizer (or any third party who may acquire Pfizer’s rights), that Pfizer (or any third party who may acquire Pfizer’s rights) will exercise its option to commercialize iSONEP, or that iSONEP will achieve the developmental, regulatory, and commercial milestones necessary to entitle us to future payments under the Pfizer Agreement on a timely basis, or at all. Even if Pfizer exercises its option, we may be required to secure substantial additional capital to continue to fund our planned drug discovery and development projects beyond 2015.

We have also entered into an at-the-market issuance sales agreement on March 18, 2014 with MLV & Co. LLC and filed a prospectus supplement under which we may sell a total of up to $23,000,000 in shares of our common stock (subject to limitations set by the SEC if the aggregate market-value of our common stock held by non-affiliates remains below $75 million).

12

Further, our expenses may exceed our current plans and expectations.  For example, while we believe we have adequate supplies of clinical material to complete the Phase 2 clinical trial for iSONEP, and to meet the requirements of the ASONEP Phase 2 clinical trial through 2014, we will probably need to manufacture additional clinical material depending on various factors, including the stability of the drug product and the length of time that patients remain on the study.

Until we can generate significant cash from operations, we expect to continue to fund our operations with cash resources generated from a combination of NIH grants, license agreements, and the proceeds of offerings of our equity and debt securities. However, we may not be successful in obtaining funding from new or existing collaboration agreements or licenses, or in receiving milestone or royalty payments under those agreements. In addition, we cannot be sure that additional financing will be available when needed or that, if available, financing will be obtained on terms favorable to us or to our stockholders. Having insufficient funds may require us to delay, scale back, or eliminate some or all of our development programs, relinquish some or even all rights to product candidates at an earlier stage of development, or renegotiate less favorable terms than we would otherwise choose. Failure to obtain adequate financing could eventually adversely affect our ability to operate as a going concern. If we raise additional funds from the issuance of equity securities, substantial dilution to our existing stockholders would likely result. If we raise additional funds by incurring debt financing, the terms of the debt may involve significant cash payment obligations as well as covenants and specific financial ratios that may restrict our ability to operate our business.

Critical Accounting Policies, Estimates, and Judgments

Our condensed consolidated financial statements are prepared in accordance with accounting principles that are generally accepted in the United States. The preparation of these condensed consolidated financial statements requires us to make estimates and judgments that affect the reported amounts of assets and liabilities, disclosure of contingent assets and liabilities at the date of the condensed consolidated financial statements, and the reported amounts of revenues and expenses during the reporting period. We continually evaluate our estimates and judgments, the most critical of which are those related to revenue recognition, valuation of long-lived assets and warrant liability, share-based compensation, the timing of the achievement of drug development milestones, and income taxes. We base our estimates and judgments on historical experience and other factors that we believe to be reasonable under the circumstances. Materially different results can occur as circumstances change and additional information becomes known.

Besides the estimates identified above that are considered critical, we make many other accounting estimates in preparing our condensed consolidated financial statements and related disclosures. All estimates, whether or not deemed critical, affect reported amounts of assets, liabilities, revenues and expenses, as well as disclosures of contingent assets and liabilities. These estimates and judgments are also based on historical experience and other factors that are believed to be reasonable under the circumstances. Materially different results can occur as circumstances change and additional information becomes known, even for estimates and judgments that are not deemed critical.

For further information, refer to the consolidated financial statements and notes thereto included in the company’s annual report on Form 10-K for the year ended December 31, 2013.

Recent Accounting Pronouncements

In May 2014, the FASB issued ASU No. 2014-09, Revenue from Contracts with Customers, a converged standard on revenue recognition. The new pronouncement requires revenue recognition to depict the transfer of promised goods or services to customer in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The guidance also specifies the accounting for some costs to obtain or fulfill a contract with a customer, as well as enhanced disclosure requirements.  ASU 2014-9 is effective for annual reporting periods beginning after December 15, 2016. Early adoption is not permitted. The adoption of ASC 2014-9 is not expected to have a material effect on our consolidated financial statements.

Item 4. CONTROLS AND PROCEDURES

Disclosure Controls and Procedures

We maintain disclosure controls and procedures that are designed to ensure that information required to be disclosed in our reports filed pursuant to the Securities Exchange Act of 1934, as amended (the “Exchange Act”) is recorded, processed, summarized, and reported within the time periods specified in the SEC’s rules and forms, and that such information is accumulated and communicated to our management, including our principal executive officer and principal financial and accounting officer, as appropriate, to allow timely decisions regarding required disclosure.

13

Under the supervision of our Chief Executive Officer and our Chief Financial Officer, and with the participation of all members of management, we conducted an evaluation of our disclosure controls and procedures, as such term is defined under Rule 13a-15(e) promulgated under the Exchange Act. Based on this evaluation, our principal executive officer and our principal financial officer concluded that our disclosure controls and procedures were effective as of the end of the period covered by this Quarterly Report on Form 10-Q.

Our management, including our Chief Executive Officer and our Chief Financial Officer, cannot be certain that our disclosure controls and procedures or our internal controls will prevent all instances of errors and fraud. A control system, no matter how well conceived and operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met. Further, the design of a control system must reflect the fact that there are resource constraints, and the benefits of controls must be considered relative to their costs. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within the company have been detected.

Changes in Internal Controls over Financial Reporting

In connection with the evaluation required by Exchange Act Rule 13a-15(d), our management, including our Chief Executive Officer and our Chief Financial Officer, concluded that no changes in our internal control over financial reporting occurred during the period covered by this report that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II — OTHER INFORMATION

Item 1. LEGAL PROCEEDINGS

We are not currently a party in any material legal proceedings.

Item 1A. RISK FACTORS

In evaluating us and our common stock, we urge you to carefully consider the risks and other information in this Quarterly Report on Form 10-Q, as well as the risk factors disclosed in Item 1A. to Part I of our Annual Report on Form 10-K for the fiscal year ended December 31, 2013, which we filed with the SEC on March 18, 2014 (the “Form 10-K”). Except as set forth below, the risks and uncertainties described in “Item 1A — Risk Factors” of our Form 10-K have not materially changed. Any of the risks discussed in this Quarterly Report on Form 10-Q or any of the risks disclosed in Item 1A. to Part I of our Form 10-K, as well as additional risks and uncertainties not currently known to us or that we currently deem immaterial, could materially and adversely affect our results of operations, financial condition or prospects.

We will require, and may not be able to obtain, substantial additional financial resources in order to carry out our planned activities.

As they are currently planned, we estimate that our ongoing drug discovery and development efforts, including general and administrative expenses, will require Lpath to expend approximately $22 million from July 1, 2014 through June 30, 2015. As of June 30, 2014, we had cash and cash equivalents totaling $14.3 million. Additional near-term sources of cash include accounts receivable of $1.3 million, additional funding from Pfizer pursuant to the terms of the Pfizer Agreement to support our Nexus clinical trial, as well as $0.3 million of unexpended funding remaining on NIH grants awarded to the company. We believe these funds should be sufficient to fund our planned drug discovery and development activities through the second quarter of 2015.

Based on our current plans and available resources, we will be required to secure additional capital to continue to fund our planned drug discovery and development projects beyond the second quarter of 2015. In addition, our expenses may exceed our current plans and expectations.  For example, while we believe we have adequate supplies of clinical material to complete the Phase 2 clinical trial for iSONEP, and we also believe we have enough clinical material to meet the requirements of the ASONEP Phase 2 clinical trial through 2014.  However, depending on various factors, including the stability of the drug product and the length of time that patients remain on the study, we will probably need to manufacture additional clinical material to complete the ASONEP Phase 2 clinical trial.

If Pfizer (or a third party who may acquire Pfizer’s rights) elects to exercise its option to continue the clinical development of iSONEP beyond the current Nexus clinical trial, the terms of the Pfizer Agreement provide that we will receive additional funding that we may use to support our operations beyond the second quarter of 2015.  However, we cannot assure you that we will be successful in maintaining our commercial relationship with Pfizer (or a third party who may acquire Pfizer’s rights), that Pfizer (or that a third party who may acquire Pfizer’s rights) will exercise its option to commercialize iSONEP prior to the end of first quarter of 2015 or at all, or that iSONEP will achieve the developmental, regulatory, and commercial milestones necessary to entitle us to future payments under the Pfizer Agreement on a timely basis, or at all.

14

In addition, we have entered into an at-the-market issuance sales agreement on March 18, 2014 with MLV & Co. LLC and filed a prospectus supplement under which we may sell a total of up to $23,000,000 in shares of our common stock (subject to limitations set by the SEC if the aggregate market-value of our common stock held by non-affiliates remains below $75 million).

We expect that we will be required to issue additional equity or debt securities or enter into other commercial arrangements, including relationships with corporate and other partners, to secure the additional financial resources to support our development efforts and future operations. We may not be successful in obtaining funding from new or existing collaboration or license agreements, or in receiving milestone or royalty payments under those agreements. In addition, we cannot be sure that additional financing will be available when needed or that, if available, financing will be obtained on terms favorable to us or to our stockholders. Having insufficient funds may require us to delay, scale back, or eliminate some or all of our development programs, relinquish some or even all rights to product candidates at an earlier stage of development, or renegotiate less favorable terms than we would otherwise choose. For example, in the future, we could determine to delay or scale back some of our planned drug discovery and development projects to extend our runway beyond the second quarter of 2015.  Failure to obtain adequate financing could eventually adversely affect our ability to operate as a going concern. If we raise additional funds from the issuance of equity securities, substantial dilution to our existing stockholders would likely result. If we raise additional funds by incurring debt financing, the terms of the debt may involve significant cash payment obligations as well as covenants and specific financial ratios that may restrict our ability to operate our business.

Item 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

None.

Item 3. DEFAULTS UPON SENIOR SECURITIES

None.

Item 4. MINE SAFETY DISCLOSURE

Not applicable

Item 5. OTHER INFORMATION

None.

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Item 6. EXHIBITS

(a)Exhibits:

The following exhibit index shows those exhibits filed with this report and those incorporated herein by reference:

2.1	Agreement and Plan of Reorganization, by and between Neighborhood Connections, Inc., Neighborhood Connections Acquisition Corporation, and Lpath Therapeutics Inc. dated July 15, 2005 (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on December 6, 2005 and incorporated herein by reference).
2.2	Acquisition Agreement and Plan of Merger, dated as of March 19, 2004, between Neighborhood Connections, Inc. and JCG, Inc. (filed as Exhibit 2.1 to the Current Report on Form 8-K filed on March 22, 2004 and incorporated herein by reference).
2.3	Plan of Conversion, dated July 17, 2014, changing the Company’s state of incorporation from the State of Nevada to the State of Delaware (filed as Exhibit 2.1 to the Current Report on Form 8-K filed on July 21, 2014 and incorporated herein by reference).
3.1	Certificate of Incorporation (filed as Exhibit 3.3 to the Current Report on Form 8-K filed on July 21, 2014 and incorporated herein by reference).
3.2	Bylaws (filed as Exhibit 3.4 to the Current Report on Form 8-K filed on July 21, 2014 and incorporated herein by reference).
4.1	Form of Common Stock Purchase Warrant for Investors in the Units. (filed as an exhibit to Form 8-K filed with the SEC on March 6, 2012 and incorporated herein by reference.)
4.2	Form of Common Stock Purchase Warrant for Placement Agents of the Units. (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 6, 2012 and incorporated herein by reference.)
4.3	Form of Warrant for Griffin Securities, Inc. (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 6, 2012 and incorporated herein by reference.)
4.1	Form of Common Stock Certificate (filed as Exhibit 4.1 to the Current Report on Form 8-K filed on July 21, 2014 and incorporated herein by reference).
10.1	Lease dated May 31, 2011 between Sorrento Science Park, LLC and Lpath, Inc. for 4025 Sorrento Valley Blvd. San Diego, California 92121 (filed as an exhibit to the Current Report on the Current Report on Form 8-K filed with the SEC on June 3, 2011 and incorporated herein by reference).
10.2	Assignment Agreement dated June 9, 2005 between Lpath Therapeutics Inc. and LPL Technologies, Inc. (filed as an exhibit to the Current Report on the Current Report on Form 8-K filed with the SEC on December 6, 2005 and incorporated herein by reference).
10.3	Research Collaboration Agreement dated August 2, 2005 between Lpath Therapeutics Inc. and AERES Biomedical Limited (filed as Exhibit 10.4 to the Current Report on Form 8-K/A filed on January 9, 2006 and incorporated herein by reference) (portions of this exhibit have been omitted pursuant to a request for confidential treatment).
10.4	Lpath, Inc. Amended and Restated 2005 Equity Incentive Plan (filed as Appendix A to the company’s Schedule 14-A Proxy Statement filed on August 28, 2007 and incorporated herein by reference).+
10.5	Assignment and Assumption Agreement dated December 1, 2005 by and between Lpath, Inc. and Lpath Therapeutics, Inc. (filed as an exhibit to the Annual Report on Form 10-KSB for the year ended December 31, 2005 filed with the SEC on March 16, 2006 and incorporated herein by reference).
10.6	Form of Employment Agreement between Lpath, Inc. and Scott R. Pancoast dated as of January 1, 2006 (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 29, 2006 and incorporated herein by reference).+

16

10.7	Form of Employment Agreement between Lpath, Inc. and Gary Atkinson dated as of February 6, 2006 (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 29, 2006 and incorporated herein by reference).+
10.8	Form of Consultant Agreement between Lpath, Inc. and Roger Sabbadini, Ph.D. dated as of June 1, 2012 (filed as Exhibit 10.1 to the Current Report on Form 8-K filed with the SEC on June 5, 2012 and incorporated herein by reference).+
10.9	Development and Manufacturing Services Agreement dated August 16, 2006 between Lpath Inc. and Laureate Pharma, Inc. (filed as Exhibit 10.13 to the Quarterly Report on Form 10-QSB for the quarter ended September 30, 2006 filed on November 13, 2006 and incorporated herein by reference) (portions of this exhibit have been omitted pursuant to a request for confidential treatment).
10.10	Securities Purchase Agreement, dated as of April 6, 2007, by and among Lpath, Inc. and each investor identified therein (filed as Exhibit 10.14 to the June 2007 SB-2 and incorporated herein by reference).
10.11	Registration Rights Agreement, dated as of April 6, 2007, by and among Lpath, Inc. and each investor identified therein (filed as Exhibit 10.15 to the June 2007 SB-2 and incorporated herein by reference).
10.12	License Agreement dated August 8, 2006 between Lonza Biologics PLC and Lpath, Inc. (filed as an exhibit to the Quarterly Report on Form 10-QSB for the quarterly period ended September 30, 2007 filed with the SEC on November 13, 2007 and incorporated herein by reference)(portions of this exhibit have been omitted pursuant to a request for confidential treatment).
10.13	Securities Purchase Agreement, dated August 12, 2008, by and among Lpath, Inc. and each of the investors identified therein (filed as Exhibit 10.17 to the registration statement on Form S-1 filed with the SEC on September 11, 2008 and incorporated herein by reference).
10.14	Registration Rights Agreement, dated August 12, 2008, by and among Lpath, Inc. and each of the investors identified therein (filed as Exhibit 10.18 to the registration statement on Form S-1 filed with the SEC on September 11, 2008 and incorporated herein by reference).
10.15	License Agreement, dated as of October 28, 2008, by and between Lpath, Inc. and Merck KgaA (filed as an exhibit to the Annual Report on Form 10-K for the year ended December 31, 2008 filed with the SEC on March 25, 2009 and incorporated herein by reference) (portions of this exhibit have been omitted pursuant to a request for confidential treatment).
10.16	Securities Purchase Agreement, dated November 16, 2010, by and between Lpath, Inc. and each purchaser identified therein (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on November 18, 2010 and incorporated herein by reference).
10.17	Registration Rights Agreement, dated November 16, 2010, by and between Lpath, Inc. and each purchaser identified therein (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on November 18, 2010 and incorporated herein by reference).
10.18	Option, License and Development Agreement, dated as of December 16, 2010, by and between Lpath, Inc. and Pfizer Inc. (filed as Exhibit 10.19 to the Annual Report on Form 10-K for the year ended December 31, 2010 filed with the SEC on March 23, 2011 and incorporated herein by reference) (portions of this exhibit have been omitted pursuant to a request for confidential treatment).
10.19	Form of Placement Agent Agreement. (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 6, 2012 and incorporated herein by reference).
10.20	Form of Subscription Agreement for U.S. investors. (filed as an exhibit to the Current Report on Form 8-K filed with the SEC on March 6, 2012 and incorporated herein by reference).

17

10.21	Financial Advisor Agreement, dated as of December 30, 2011 by and between Lpath, Inc. and Griffin Securities, Inc. (filed as an exhibit to the registration statement on Form S-1/A filed with the SEC on February 10, 2012 and incorporated herein by reference).
10.22	Form of Indemnification Agreement for directors and officers under Nevada law (filed as an exhibit to Form 8-K filed with the SEC on October 26, 2012 and incorporated herein by reference).+
10.23	Amendment to Option, License and Development Agreement, dated December 5, 2012, by and between Lpath, Inc. and Pfizer Inc (filed as Exhibit 10.24 to the Annual Report on Form 10-K for the year ended December 31, 2012 filed with the SEC on March 15, 2013 and incorporated herein by reference).
10.24	At-The-Market Issuance Sales Agreement, dated as of August 15, 2013 by and between MLV & Co. LLC, JMP Securities LLC and Lpath, Inc. (filed as an exhibit to the Registration Statement on Form S-3 filed with the SEC on August 15, 2013 and incorporated herein by reference).
10.25	At-The-Market Issuance Sales Agreement, dated as of March 18, 2014 by and between MLV & Co. LLC and Lpath, Inc. (filed as Exhibit 10.25 to the Annual Report on Form 10-K for the year ended December 31, 2013 filed with the SEC on March 18, 2014 and incorporated herein by reference).
10.26	First Amendment to Employment Agreement, between Lpath, Inc. and Gary Atkinson, entered into as of March 17, 2014 (filed as Exhibit 10.26 to the Annual Report on Form 10-K for the year ended December 31, 2013 filed with the SEC on March 18, 2014 and incorporated herein by reference). +
10.27	Form of Option Agreement, between the Lpath, Inc. and its officers and directors (filed as Exhibit 10.27 to the Annual Report on Form 10-K for the year ended December 31, 2013 filed with the SEC on March 18, 2014 and incorporated herein by reference). +
10.28	Employment Agreement, dated as of April 15, 2013 by and between Lpath, Inc. and Dario A. Paggiarino, M.D. (filed as Exhibit 10.28 to the Annual Report on Form 10-K for the year ended December 31, 2013 filed with the SEC on March 18, 2014 and incorporated herein by reference).+
10.29	Form of Indemnification Agreement for directors and officers under Delaware law (filed as Exhibit 10.1 to the Current Report on Form 8-K filed on July 21, 2014 and incorporated herein by reference).+
31.1	Section 302 Certification by Chief Executive Officer of Lpath, Inc.*
31.2	Section 302 Certification by Chief Financial Officer of Lpath, Inc.*
32.1	Section 906 Certification by Chief Executive Officer and Chief Financial Officer of Lpath, Inc.*
101.INS# XBRL	Instance Document
101.SCH# XBRL	Taxonomy Extension Schema Document
101.CAL# XBRL	Taxonomy Extension Calculation Linkbase Document
101.DEF# XBRL	Taxonomy Extension Definition Linkbase Document
101.LAB# XBRL	Taxonomy Extension Label Linkbase Document
101.PRE# XBRL	Taxonomy Extension Presentation Linkbase Document

+Management contract or compensation plan or arrangement

*Provided herewith.

18

(c)Financial Statement Schedules

All financial statement schedules are omitted because they are not applicable or the required information is shown in the consolidated financial statements or other notes hereto.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated.

	Lpath, Inc.
Date: August 8, 2014	/S/ SCOTT R. PANCOAST
	Scott R. Pancoast
	President and Chief Executive Officer
	(Principal Executive Officer)
	/S/ GARY J. G. ATKINSON
	Gary J. G. Atkinson,
	Senior Vice President and Chief Financial Officer
	(Principal Financial and Accounting Officer)

19

EX-31.1

Exhibit 31.1

CERTIFICATION

I, Scott R. Pancoast, Chief Executive Officer of Lpath, Inc. (the “Registrant”), certify that:

1.I have reviewed this quarterly report on Form 10-Q of the Registrant;

2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Registrant as of, and for, the periods presented in this report.

4.The Registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Registrant and have:

a)Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b)Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c)Evaluated the effectiveness of the Registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

d)Disclosed in this report any change in the Registrant’s internal control over financial reporting that occurred during the Registrant’s most recent fiscal quarter (the Registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the Registrant’s internal control over financial reporting.

5.The Registrant’s other certifying officers and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Registrant’s auditors and the audit committee of the Registrant’s board of directors (or persons performing the equivalent functions):

(a)All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Registrant’s ability to record, process, summarize and report financial information; and

(b)Any fraud, whether or not material, that involves management or other employees who have a significant role in the Registrant’s internal control over financial reporting.

Date: August 8, 2014	By:	/S/ SCOTT R. PANCOAST
		Scott R. Pancoast
		President and Chief Executive Officer
		(Principal Executive Officer)

EX-31.2

Exhibit 31.2

CERTIFICATION

I, Gary J. G. Atkinson, Chief Financial Officer of Lpath, Inc. (the “Registrant”), certify that:

1.I have reviewed this quarterly report on Form 10-Q of the Registrant;

2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Registrant as of, and for, the periods presented in this report.

4.The Registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Registrant and have:

a)Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b)Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c)Evaluated the effectiveness of the Registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

d)Disclosed in this report any change in the Registrant’s internal control over financial reporting that occurred during the Registrant’s most recent fiscal quarter (the Registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the Registrant’s internal control over financial reporting.

5.The Registrant’s other certifying officers and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Registrant’s auditors and the audit committee of the Registrant’s board of directors (or persons performing the equivalent functions):

(a)All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Registrant’s ability to record, process, summarize and report financial information; and

(b)Any fraud, whether or not material, that involves management or other employees who have a significant role in the Registrant’s internal control over financial reporting.

Date: August 8, 2014	By:	/S/ GARY J. G. ATKINSON
		Gary J. G. Atkinson
		Senior Vice President and Chief Financial Officer
		(Principal Financial and Accounting Officer)

EX-32.1

Exhibit 32.1

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350

In connection with the Quarterly Report of Lpath, Inc. (the “Corporation”) on Form 10-Q for the period ended June 30, 2014 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Scott R. Pancoast, President and Chief Executive Officer and I, Gary J. G. Atkinson, Vice President and Chief Financial Officer, of the Corporation, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to our knowledge:

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Corporation.

Date: August 8, 2014
	/S/ SCOTT R. PANCOAST
	Scott R. Pancoast
	President and Chief Executive Officer
	/S/ GARY J. G. ATKINSON
	Gary J. G. Atkinson
	Senior Vice President and Chief Financial Officer

A signed original of this written statement required by Section 906 has been provided to Lpath, Inc. and will be retained by Lpath, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

This certification accompanies the Form 10-Q to which it relates, is not deemed filed with the Securities and Exchange Commission and is not to be incorporated by reference into any filing of Lpath, Inc. under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before or after the date of the Form 10-Q), irrespective of any general incorporation language contained in such filing.

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FAIR VALUE MEASUREMENTS

6 Months Ended

Jun. 30, 2014

FAIR VALUE MEASUREMENTS

FAIR VALUE MEASUREMENTS

Note 4 — FAIR VALUE MEASUREMENTS

Lpath has issued warrants, of which some are classified as equity and some as liabilities.  The warrants issued in March 2012 (and expiring in March 2017) provide that in the event of a fundamental transaction, as defined by the warrant agreement, the company may, under certain circumstances, be obligated to settle the March 2012 warrants for cash equal to the value of the warrants determined in accordance with the warrant agreement.  The company’s recurring fair value measurements at June 30, 2014 were as follows:

	Fair Value as of June 30, 2014		Significant Unobservable Inputs (Level 3)
Liabilities:
Warrants expiring March 2017	$	1,700,000	$	1,700,000

The company determined the fair value of the warrant liability for certain warrants, as applicable, using a Black-Scholes model. The model considered amounts and timing of future possible equity and warrant issuances and volatility of the company’s stock price equal to 100%, as specified in the underlying warrants.

Recurring Level 3 Activity, Reconciliation, and Basis for Valuation

The table below provides a reconciliation of the beginning and ending balances for the liabilities measured at fair value using significant unobservable inputs (Level 3).

Fair value measurements using significant unobservable inputs (Level 3):

Liabilities:
Warrant liability as of January 1, 2014	$	2,100,000
Change in fair value of warrants	(400,000		)
Warrant liability as of June 30, 2014	$	1,700,000

The company determined the fair value of the warrant liability for certain warrants, as applicable, using a Black-Scholes model. The model considered amounts and timing of future possible equity and warrant issuances and historical volatility of the company’s stock price.

The terms of all outstanding warrants permit the company, upon exercise of the warrants, to settle the contract by the delivery of unregistered shares. During the three months ended June 30, 2014, 5,715 warrants expired.  As of June 30, 2014, there were 924,241 warrants outstanding with a weighted-average exercise price of $7.58 per share expiring through May 2017.

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SHARE-BASED PAYMENTS

6 Months Ended

Jun. 30, 2014

SHARE-BASED PAYMENTS

SHARE-BASED PAYMENTS

Note 3 — SHARE-BASED PAYMENTS

The company recognized share-based compensation expense as follows:

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Research and development	$	232,913	$	122,849	$	118,261	$	82,439
General and administrative	471,313		279,910		268,164		126,434
Total share-based compensation expense	$	704,226	$	402,759	$	386,425	$	208,873

As of June 30, 2014, there was a total of $2.4 million in unrecognized compensation expense related to unvested stock-based compensation under the Lpath, Inc. Amended and Restated 2005 Equity Incentive Plan. That expense is expected to be recognized over a weighted-average period of 2.5 years. Because of its net operating loss carryforwards, the company did not realize any tax benefits for the tax deductions from share-based payment arrangements during the three-month periods ended June 30, 2014 and 2013.

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Condensed Consolidated Balance Sheets (USD $)	Jun. 30, 2014	Dec. 31, 2013
Current Assets:
Cash and cash equivalents	$ 14,263,475	$ 11,851,639
Accounts receivable	1,313,503	1,310,037
Prepaid expenses and other current assets	417,988	292,477
Total current assets	15,994,966	13,454,153
Equipment and leasehold improvements, net	260,924	211,362
Patents, net	2,074,192	1,926,868
Deposits and other assets	77,350	77,350
Total assets	18,407,432	15,669,733
Current Liabilities:
Accounts payable	2,544,122	2,025,799
Accrued compensation	416,991	693,022
Accrued expenses	270,347	291,358
Deferred contract revenue, current portion	250,000	498,000
Deferred rent, short-term portion	28,804	24,008
Total current liabilities	3,510,264	3,532,187
Deferred rent, long-term portion	54,971	69,373
Warrants	1,700,000	2,100,000
Total liabilities	5,265,235	5,701,560
Stockholders' Equity:
Common stock - $.001 par value; 100,000,000 shares authorized; 15,591,161 and 13,387,914 issued and outstanding at June 30, 2014 and December 31, 2013, respectively	15,591	13,388
Additional paid-in capital	69,631,214	59,432,943
Accumulated deficit	(56,504,608)	(49,478,158)
Total stockholders' equity	13,142,197	9,968,173
Total liabilities and stockholders' equity	$ 18,407,432	$ 15,669,733

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BASIS FOR PRESENTATION

6 Months Ended

Jun. 30, 2014

BASIS FOR PRESENTATION

BASIS FOR PRESENTATION

Note 1 — BASIS FOR PRESENTATION

The unaudited condensed consolidated balance sheet of Lpath, Inc. (“Lpath” or “the company”) as of December 31, 2013 was derived from our audited financial statements, but does not contain all disclosures required by accounting principles generally accepted in the United States of America, and certain information and disclosures normally included have been condensed or omitted pursuant to the rules and regulations of the SEC.

In the opinion of management, all adjustments considered necessary for a fair presentation have been included. Except as otherwise disclosed, all such adjustments are of a normal recurring nature. Operating results for the three-month and six-month periods ended June 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014 or for any future financial period. For further information, refer to the consolidated financial statements and notes included in the company’s annual report on Form 10-K for the year ended December 31, 2013.

The preparation of the consolidated financial statements in conformity with U.S. generally accepted accounting principles (“GAAP”) requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

Recent Accounting Pronouncements

In May 2014, the FASB issued ASU No. 2014-09, Revenue from Contracts with Customers, a converged standard on revenue recognition. The new pronouncement requires revenue recognition to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The guidance also specifies the accounting for some costs to obtain or fulfil a contract with a customer, as well as enhanced disclosure requirements.  ASU 2014-9 is effective for annual reporting periods beginning after December 15, 2016. Early adoption is not permitted. The adoption of ASC 2014-9 is not expected to have a material effect on our consolidated financial statements.

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RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

6 Months Ended

Jun. 30, 2014

RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

Note 2 — RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

In 2010, Lpath entered into an agreement providing Pfizer Inc. (“Pfizer”) with an exclusive option for a worldwide license to develop and commercialize iSONEP™ (“the Pfizer Agreement”), Lpath’s lead monoclonal antibody product candidate that is being evaluated for the treatment of wet age-related macular degeneration (“wet AMD”) and other ocular disorders.

Following completion of the clinical trial, Pfizer has the right to exercise its option for worldwide rights to iSONEP for an undisclosed option fee and, if Pfizer exercises its option, Lpath will be eligible to receive development, regulatory, and commercial milestone payments that could total up to $497.5 million.  In addition, Lpath will be entitled to receive tiered double-digit royalties based on sales of iSONEP. As part of the agreement, Lpath has granted to Pfizer a time-limited right of first refusal for ASONEP™, Lpath’s product candidate that is being evaluated for the treatment of cancer.

The company recognized revenue under research and development collaborative agreements as follows:

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Cost reimbursements	$	2,487,386	$	—	$	1,008,109	$	—
Amortization of license and development fees	248,000		2,491,015		124,000		1,603,425
Other	—		60,096		—		60,096
	$	2,735,386	$	2,551,111	$	1,132,109	$	1,663,521

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Condensed Consolidated Balance Sheets (Parenthetical) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Condensed Consolidated Balance Sheets
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized	100,000,000	100,000,000
Common stock, shares issued	15,591,161	13,387,914
Common stock, shares outstanding	15,591,161	13,387,914

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SHARE-BASED PAYMENTS (Details) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Share-based compensation expense
Total share-based compensation expense	$ 386,425	$ 208,873	$ 704,226	$ 402,759
Unrecognized compensation expense related to unvested stock-based compensation	2,400,000		2,400,000
Weighted average period to recognize unrecognized stock-based compensation expense			2 years 6 months
Research and Development Expense [Member]
Share-based compensation expense
Total share-based compensation expense	118,261	82,439	232,913	122,849
General and Administrative Expense [Member]
Share-based compensation expense
Total share-based compensation expense	$ 268,164	$ 126,434	$ 471,313	$ 279,910

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Document and Entity Information	3 Months Ended
	Jun. 30, 2014	Aug. 08, 2014
Document and Entity Information
Entity Registrant Name	LPATH, INC
Entity Central Index Key	0001251769
Document Type	10-Q
Document Period End Date	Jun. 30, 2014
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Entity Current Reporting Status	Yes
Entity Filer Category	Smaller Reporting Company
Entity Common Stock, Shares Outstanding		15,618,666
Document Fiscal Year Focus	2014
Document Fiscal Period Focus	Q2

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FAIR VALUE MEASUREMENTS (Details) (USD $)	6 Months Ended
	Jun. 30, 2014
Liabilities:
Volatility of stock price as specified in the underlying warrants (as a percent)	100.00%
Fair Value, Measurements, Recurring [Member] | Estimate of Fair Value Measurement [Member] | Warrant [Member] | March 2017 [Member]
Liabilities:
Fair value of liabilities	$ 1,700,000
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member] | Warrant [Member] | March 2017 [Member]
Liabilities:
Fair value of liabilities	$ 1,700,000

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Condensed Consolidated Statements of Operations (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Revenues:
Grant and royalty revenue	$ 199,984	$ 353,075	$ 316,083	$ 577,295
Research and development revenue under collaborative agreements	1,132,109	1,663,521	2,735,386	2,551,111
Total revenues	1,332,093	2,016,596	3,051,469	3,128,406
Expenses:
Research and development	4,574,964	2,839,477	8,237,972	4,424,161
General and administrative	1,083,008	1,108,887	2,239,965	2,112,742
Total expenses	5,657,972	3,948,364	10,477,937	6,536,903
Loss from operations	(4,325,879)	(1,931,768)	(7,426,468)	(3,408,497)
Other income (expense), net	18		18	27,022
Change in fair value of warrants	600,000	550,000	400,000	750,000
Total other income (expense), net	600,018	550,000	400,018	777,022
Net loss	$ (3,725,861)	$ (1,381,768)	$ (7,026,450)	$ (2,631,475)
Basic and diluted net loss per share (in dollars per share)	$ (0.23)	$ (0.10)	$ (0.46)	$ (0.20)
Weighted-average shares outstanding used in the calculation (in shares)	15,865,634	13,419,512	15,192,395	13,410,696

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RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS (Tables)

6 Months Ended

Jun. 30, 2014

RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS

Schedule of recognized revenue under research and development collaborative agreements

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Cost reimbursements	$	2,487,386	$	—	$	1,008,109	$	—
Amortization of license and development fees	248,000		2,491,015		124,000		1,603,425
Other	—		60,096		—		60,096
	$	2,735,386	$	2,551,111	$	1,132,109	$	1,663,521

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EARNINGS PER SHARE

6 Months Ended

Jun. 30, 2014

EARNINGS PER SHARE

EARNINGS PER SHARE

Note 6 — EARNINGS PER SHARE

Anti-dilutive common stock equivalents were excluded from the calculation of diluted loss per share as follows:

	Six and Three Months Ended
	June 30,
Stock options	802,829	362,469
Warrants	924,241	1,261,874
Restricted stock units	636,209	713,989
Total	2,363,279	2,338,332

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FAIR VALUE MEASUREMENTS (Details 2) (Warrant [Member], USD $)	3 Months Ended	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2014
Warrant [Member]
Liabilities:
Balance at the beginning of the period		$ 2,100,000
Change in fair value of warrants		(400,000)
Balance at the end of the period	$ 1,700,000	$ 1,700,000
Number of warrants expired (in shares)	5,715
Number of warrants outstanding (in shares)	924,241	924,241
Weighted-average exercise price of warrant outstanding (in dollars per share)	7.58	7.58

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EARNINGS PER SHARE (Tables)

6 Months Ended

Jun. 30, 2014

EARNINGS PER SHARE

Schedule of anti-dilutive common stock equivalents that were excluded from the calculation of diluted loss per share

	Six and Three Months Ended
	June 30,
Stock options	802,829	362,469
Warrants	924,241	1,261,874
Restricted stock units	636,209	713,989
Total	2,363,279	2,338,332

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SHARE-BASED PAYMENTS (Tables)

6 Months Ended

Jun. 30, 2014

SHARE-BASED PAYMENTS

Schedule of recognized share-based compensation expense

	Six Months Ended				Three Months Ended
	June 30,				June 30,
	2014		2013		2014		2013
Research and development	$	232,913	$	122,849	$	118,261	$	82,439
General and administrative	471,313		279,910		268,164		126,434
Total share-based compensation expense	$	704,226	$	402,759	$	386,425	$	208,873

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FAIR VALUE MEASUREMENTS (Tables)

6 Months Ended

Jun. 30, 2014

FAIR VALUE MEASUREMENTS

Schedule of recurring fair value measurements

	Fair Value as of June 30, 2014		Significant Unobservable Inputs (Level 3)
Liabilities:
Warrants expiring March 2017	$	1,700,000	$	1,700,000

Schedule of fair value measurements using significant unobservable inputs (Level 3)

Liabilities:
Warrant liability as of January 1, 2014	$	2,100,000
Change in fair value of warrants	(400,000		)
Warrant liability as of June 30, 2014	$	1,700,000

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RESEARCH AND DEVELOPMENT COLLABORATIVE AGREEMENTS (Details) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Research and development collaborative agreements
Total recognized revenue	$ 1,132,109	$ 1,663,521	$ 2,735,386	$ 2,551,111
Collaborative Arrangement [Member] | Pfizer Inc [Member]
Research and development collaborative agreements
Cost reimbursements	1,008,109		2,487,386
Amortization of license and development fees	124,000	1,603,425	248,000	2,491,015
Other		60,096		60,096
Collaborative Arrangement [Member] | Pfizer Inc [Member] | Maximum [Member]
Research and development collaborative agreements
Eligible milestone payment to be received, on exercise of option for worldwide rights to iSONEP by counterparty	$ 497,500,000		$ 497,500,000

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EARNINGS PER SHARE (Details)	3 Months Ended	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2014
Anti-dilutive securities excluded from the calculation of diluted income (loss) per share
Anti-dilutive common stock equivalents (in shares)	2,338,332	2,363,279
Employee and Directors and Outside Consultants Stock Options [Member]
Anti-dilutive securities excluded from the calculation of diluted income (loss) per share
Anti-dilutive common stock equivalents (in shares)	362,469	802,829
Warrant [Member]
Anti-dilutive securities excluded from the calculation of diluted income (loss) per share
Anti-dilutive common stock equivalents (in shares)	1,261,874	924,241
Restricted Stock [Member]
Anti-dilutive securities excluded from the calculation of diluted income (loss) per share
Anti-dilutive common stock equivalents (in shares)	713,989	636,209

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Condensed Consolidated Statements of Cash Flows (USD $)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Cash flows from operating activities:
Net loss	$ (7,026,450)	$ (2,631,475)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	704,226	402,759
Change in fair value of warrants	(400,000)	(750,000)
Depreciation and amortization	98,948	129,047
Changes in operating assets and liabilities:
Accounts receivable	(3,466)	(148,490)
Prepaid expenses and other current assets	(125,511)	113,379
Accounts payable and accrued expenses	195,364	(1,437,809)
Deferred contract revenue	(248,000)	(2,491,016)
Other	(9,606)	(36,919)
Net cash used in operating activities	(6,814,495)	(6,850,524)
Cash flows from investing activities:
Equipment and leasehold improvement expenditures	(99,007)	(37,734)
Patent expenditures	(196,827)	(185,564)
Net cash used in investing activities	(295,834)	(223,298)
Cash flows from financing activities:
Proceeds from sale of common stock and warrants, net	9,604,892
Proceeds from options and warrants exercised	250	3,289
Payment for restricted stock tax liability on net settlement	(82,977)	(44,833)
Net cash provided by financing activities	9,522,165	(41,544)
Net (decrease) increase in cash and cash equivalents	2,411,836	(7,115,366)
Cash and cash equivalents at beginning of period	11,851,639	24,621,083
Cash and cash equivalents at end of period	14,263,475	17,505,717
Cash paid during the year for:
Income taxes	1,600	1,600
Supplemental disclosure of non-cash investing and financing activities:
Change in fair value of warrant liability	$ (400,000)	$ (750,000)

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COMMON STOCK

6 Months Ended

Jun. 30, 2014

COMMON STOCK

COMMON STOCK

Note 5 — COMMON STOCK

On March 18, 2014, Lpath entered into an at-the-market issuance sales agreement with MLV (the “MLV Agreement”). Pursuant to the MLV Agreement, the company may issue and sell shares of its common stock having an aggregate offering price of up to $23 million (subject to limitations set by the SEC if the aggregate market-value of the company’s common stock held by non-affiliates remains below $75 million) from time to time, at the company’s option, through MLV. Sales of common stock through MLV, if any, will be made by any method that is deemed an “at-the-market” offering as defined in Rule 415 promulgated under the Securities Act of 1933, as amended, including by means of ordinary brokers’ transactions at market prices, in block transactions or as otherwise agreed by the Lpath and MLV. Subject to the terms and conditions of the MLV Agreement, MLV will use commercially reasonable efforts to sell the common stock based upon the company’s instructions (including any price, time or size limits or other customary parameters or conditions the Company may impose). Lpath is not obligated to make any sales of its common stock under the MLV Agreement. Any shares sold will be sold pursuant to the company’s effective shelf registration statement on Form S-3. The company will pay MLV a commission of up to 3.0% of the gross proceeds. The MLV Agreement will terminate upon the earlier of the sale of all common stock subject to the MLV Agreement or termination of the MLV Agreement by the company or MLV. During the quarter ended June 30, 2014, the company sold 268,840 shares at sales prices ranging from $4.25 to $4.76 per share, resulting in $1,189,000 in net proceeds. From July 1, 2014 to August 8, 2014, the company sold 27,505 shares at sales prices ranging from $3.50 to $4.08 per share, resulting in $99,000 in net proceeds.

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COMMON STOCK (Details) (USD $)	2 Months Ended			3 Months Ended		0 Months Ended	6 Months Ended		0 Months Ended
	Aug. 31, 2014 Subsequent Event [Member]	Aug. 08, 2014 Minimum [Member] Subsequent Event [Member]	Aug. 08, 2014 Maximum [Member] Subsequent Event [Member]	Jun. 30, 2014 MLV and CO LLC [Member]	Jun. 30, 2014 MLV and CO LLC [Member] Minimum [Member]	Mar. 18, 2014 MLV and CO LLC [Member] Maximum [Member]	Jun. 30, 2013 MLV and CO LLC [Member] Maximum [Member]	Jun. 30, 2014 MLV and CO LLC [Member] Maximum [Member]	Mar. 18, 2014 Non Affiliates [Member] Maximum [Member]
Aggregate offering price						$ 23,000,000
Common stock held by non-affiliates									75,000,000
Commission payable as a percentage of gross proceeds							3.00%
Common stock, shares issued	27,505			268,840
Sales price (in dollars per share)		$ 3.50	$ 4.08		$ 4.25			$ 4.76
Gross proceeds	$ 99,000			$ 1,189,000