0001214659-23-007174.txt : 20230515 0001214659-23-007174.hdr.sgml : 20230515 20230515160025 ACCESSION NUMBER: 0001214659-23-007174 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20230331 FILED AS OF DATE: 20230515 DATE AS OF CHANGE: 20230515 EFFECTIVENESS DATE: 20230515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: TANG CAPITAL MANAGEMENT LLC CENTRAL INDEX KEY: 0001232621 IRS NUMBER: 461592449 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-14822 FILM NUMBER: 23921689 BUSINESS ADDRESS: STREET 1: 4747 EXECUTIVE DRIVE STREET 2: SUITE 210 CITY: SAN DIEGO STATE: CA ZIP: 92121 BUSINESS PHONE: 858-200-3830 MAIL ADDRESS: STREET 1: 4747 EXECUTIVE DRIVE STREET 2: SUITE 210 CITY: SAN DIEGO STATE: CA ZIP: 92121 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001232621 XXXXXXXX 03-31-2023 03-31-2023 false TANG CAPITAL MANAGEMENT LLC
4747 Executive Drive Suite 210 San Diego CA 92121
13F HOLDINGS REPORT 028-14822 N
Kevin Tang Manager 858-200-3830 /s/ Kevin Tang San Diego CA 05-15-2023 1 103 671118737 1 0001178579 028-14818 TANG KEVIN C
INFORMATION TABLE 2 infotable.xml 2SEVENTY BIO INC COMMON STOCK 901384107 2550000 250000 SH OTR 1 0 250000 0 ACELRX PHARMACEUTICALS INC COM NEW 00444T209 128310 195000 SH OTR 1 0 195000 0 ADICET BIO INC COM 007002108 14515200 2520000 SH OTR 1 0 2520000 0 ALIGOS THERAPEUTICS INC COM 01626L105 2993275 3424800 SH OTR 1 0 3424800 0 ALLAKOS INC COM 01671P100 1993453 447967 SH OTR 1 0 447967 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 9014400 45000 SH OTR 1 0 45000 0 ALTIMMUNE INC COM NEW 02155H200 11605000 2750000 SH OTR 1 0 2750000 0 AMARIN CORP PLC SPONS ADR NEW 023111206 8100000 5400000 SH OTR 1 0 5400000 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 2934000 100000 SH OTR 1 0 100000 0 ANAPTYSBIO INC COM 032724106 44228527 2032561 SH OTR 1 0 2032561 0 ARCUS BIOSCIENCES INC COM 03969F109 2698061 147920 SH OTR 1 0 147920 0 ARS PHARMACEUTICALS INC COM 82835W108 2665604 409463 SH OTR 1 0 409463 0 ARVINAS INC COM 04335A105 2185600 80000 SH OTR 1 0 80000 0 ASLAN PHARMACEUTICALS LTD SPON ADS NEW 04522R200 3356067 1165301 SH OTR 1 0 1165301 0 ASTRAZENECA PLC SPONSORED ADR 046353108 11799700 170000 SH OTR 1 0 170000 0 ATEA PHARMACEUTICALS INC COM 04683R106 3358650 1002582 SH OTR 1 0 1002582 0 ATHIRA PHARMA INC COM 04746L104 881788 352715 SH OTR 1 0 352715 0 ATYR PHARMA INC COM NEW 002120202 259203 123430 SH OTR 1 0 123430 0 AVROBIO INC COM 05455M100 37613 37613 SH OTR 1 0 37613 0 AXSOME THERAPEUTICS INC COM 05464T104 19737600 320000 SH OTR 1 0 320000 0 BANKUNITED INC COM 06652K103 2258000 100000 SH OTR 1 0 100000 0 BEIGENE LTD SPONSORED ADR 07725L102 18320050 85000 SH OTR 1 0 85000 0 BELLEROPHON THERAPEUTICS INC COM NEW 078771300 7053455 893974 SH OTR 1 0 893974 0 BELLUS HEALTH INC NEW COM NEW 07987C204 2160000 300000 SH OTR 1 0 300000 0 BIO RAD LABS INC CL A 090572207 7664320 16000 SH OTR 1 0 16000 0 BIOATLA INC COM 09077B104 9712524 3624076 SH OTR 1 0 3624076 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 13344000 1600000 SH OTR 1 0 1600000 0 BIOHAVEN LTD COM G1110E107 1912400 140000 SH OTR 1 0 140000 0 BLUEBIRD BIO INC COM 09609G100 31427390 9882827 SH OTR 1 0 9882827 0 BOLT BIOTHERAPEUTICS INC COM 097702104 2262299 1627553 SH OTR 1 0 1627553 0 CAPITAL ONE FINL CORP COM 14040H105 9616000 100000 SH OTR 1 0 100000 0 CITIGROUP INC COM NEW 172967424 4689000 100000 SH OTR 1 0 100000 0 COHERUS BIOSCIENCES INC COM 19249H103 1368000 200000 SH OTR 1 0 200000 0 COMERICA INC COM 200340107 5797656 133525 SH OTR 1 0 133525 0 CYTOMX THERAPEUTICS INC COM 23284F105 9200478 6093032 SH OTR 1 0 6093032 0 CULLINAN ONCOLOGY INC COM 230031106 5115000 500000 SH OTR 1 0 500000 0 CVB FINL CORP COM 126600105 3336000 200000 SH OTR 1 0 200000 0 CYTEIR THERAPEUTICS INC COM 23284P103 182000 100000 SH OTR 1 0 100000 0 DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 2943000 300000 SH OTR 1 0 300000 0 EAGLE PHARMACEUTICALS INC COM 269796108 2269600 80000 SH OTR 1 0 80000 0 ELEVATION ONCOLOGY INC COM 28623U101 2660000 1400000 SH OTR 1 0 1400000 0 ENANTA PHARMACEUTICALS INC COM 29251M106 3639600 90000 SH OTR 1 0 90000 0 ENZO BIOCHEM INC COM 294100102 5589000 2300000 SH OTR 1 0 2300000 0 EQUILLIUM INC COM 29446K106 64655 88568 SH OTR 1 0 88568 0 EQUITY COMWLTH COM SH BEN INT 294628102 2071000 100000 SH OTR 1 0 100000 0 ESPERION THERAPEUTICS INC NE COM 29664W105 2941500 1850000 SH OTR 1 0 1850000 0 EVOLUS INC COM 30052C107 27049996 3197399 SH OTR 1 0 3197399 0 FATE THERAPEUTICS INC COM 31189P102 3990000 700000 SH OTR 1 0 700000 0 FIRST REP BK SAN FRANCISCO C COM 33616C100 3899838 278759 SH OTR 1 0 278759 0 GALAPAGOS NV SPON ADR 36315X101 3464076 89650 SH OTR 1 0 89650 0 GENFIT S A ADS 372279109 4971312 1212515 SH OTR 1 0 1212515 0 GRAPHITE BIO INC COM 38870X104 4969742 2028466 SH OTR 1 0 2028466 0 HARMONY BIOSCIENCES HLDGS IN COM 413197104 10487180 321200 SH OTR 1 0 321200 0 HERON THERAPEUTICS INC COM 427746102 830500 550000 SH OTR 1 0 550000 0 IMMUNITYBIO INC COM 45256X103 1994347 1095795 SH OTR 1 0 1095795 0 IMMUNOCORE HLDGS PLC ADS 45258D105 20052864 405600 SH OTR 1 0 405600 0 IMMUNOGEN INC COM 45253H101 4895436 1274853 SH OTR 1 0 1274853 0 INSMED INC COM PAR $.01 457669307 2833761 166203 SH OTR 1 0 166203 0 INSPIRATO INCORPORATED COM CL A 45791E107 364382 380000 SH OTR 1 0 380000 0 INSTIL BIO INC COM 45783C101 132160 200000 SH OTR 1 0 200000 0 INTRA-CELLULAR THERAPIES INC COM 46116X101 16245000 300000 SH OTR 1 0 300000 0 INVIVYD INC COM 00534A102 480000 400000 SH OTR 1 0 400000 0 IONIS PHARMACEUTICALS INC COM 462222100 7148000 200000 SH OTR 1 0 200000 0 ITEOS THERAPEUTICS INC COM 46565G104 2949287 216700 SH OTR 1 0 216700 0 JOUNCE THERAPEUTICS INC COM 481116101 9805161 5300087 SH OTR 1 0 5300087 0 KALVISTA PHARMACEUTICALS INC COM 483497103 20839949 2651393 SH OTR 1 0 2651393 0 KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 6456000 600000 SH OTR 1 0 600000 0 KRONOS BIO INC COM 50107A104 292000 200000 SH OTR 1 0 200000 0 LIANBIO SPONSORED ADS 53000N108 410816 209600 SH OTR 1 0 209600 0 LILLY ELI & CO COM 532457108 10302600 30000 SH OTR 1 0 30000 0 MAGENTA THERAPEUTICS INC COM 55910K108 4807935 6050000 SH OTR 1 0 6050000 0 MEI PHARMA INC COM NEW 55279B202 1181915 5163456 SH OTR 1 0 5163456 0 MIRUM PHARMACEUTICALS INC COM 604749101 28103400 1170000 SH OTR 1 0 1170000 0 MODERNA INC COM 60770K107 20994386 136700 SH OTR 1 0 136700 0 MOLECULAR PARTNERS AG ADS 60853G106 230968 38253 SH OTR 1 0 38253 0 NEKTAR THERAPEUTICS COM 640268108 98125 139600 SH OTR 1 0 139600 0 NEXTCURE INC COM 65343E108 592000 400000 SH OTR 1 0 400000 0 NEW YORK CMNTY BANCORP INC COM 649445103 14523664 1606600 SH OTR 1 0 1606600 0 NKARTA INC COM 65487U108 6339693 1785829 SH OTR 1 0 1785829 0 NOVO-NORDISK A S ADR 670100205 21483900 135000 SH OTR 1 0 135000 0 ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200 268500 50000 SH OTR 1 0 50000 0 PARDES BIOSCIENCES INC COM 69945Q105 396000 300000 SH OTR 1 0 300000 0 PASSAGE BIO INC COM 702712100 287310 300000 SH OTR 1 0 300000 0 PROMETHEUS BIOSCIENCES INC COM 74349U108 2253720 21000 SH OTR 1 0 21000 0 PYXIS ONCOLOGY INC COMMON STOCK 747324101 9951465 2481662 SH OTR 1 0 2481662 0 QUINCE THERAPEUTICS INC COM 22053A107 5647200 3620000 SH OTR 1 0 3620000 0 REVIVA PHARMACEUTCLS HLDGS I COM 76152G100 222908 53200 SH OTR 1 0 53200 0 SCYNEXIS INC COM NEW 811292200 1149537 383179 SH OTR 1 0 383179 0 SERVISFIRST BANCSHARES INC COM 81768T108 1638900 30000 SH OTR 1 0 30000 0 STELLAR BANCORP INC COM 858927106 246100 10000 SH OTR 1 0 10000 0 SURFACE ONCOLOGY INC COM 86877M209 908440 1300000 SH OTR 1 0 1300000 0 TANGO THERAPEUTICS INC COM 87583X109 790000 200000 SH OTR 1 0 200000 0 TARSUS PHARMACEUTICALS INC COM 87650L103 25569366 2034158 SH OTR 1 0 2034158 0 TCR2 THERAPEUTICS INC COM 87808K106 5099618 3399745 SH OTR 1 0 3399745 0 THIRD HARMONIC BIO INC COM 88427A107 7416000 1800000 SH OTR 1 0 1800000 0 TONIX PHARMACEUTICALS HLDG C COM NEW 890260862 650458 1100419 SH OTR 1 0 1100419 0 UMB FINL CORP COM 902788108 1154400 20000 SH OTR 1 0 20000 0 VANDA PHARMACEUTICALS INC COM 921659108 679000 100000 SH OTR 1 0 100000 0 VAXCYTE INC COM 92243G108 11244000 300000 SH OTR 1 0 300000 0 VERITEX HLDGS INC COM 923451108 2008600 110000 SH OTR 1 0 110000 0 VINCERX PHARMA INC COM NEW 92731L106 105832 101762 SH OTR 1 0 101762 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 17628012 692925 SH OTR 1 0 692925 0 ZYMEWORKS DEL INC COM 98985Y108 9944000 1100000 SH OTR 1 0 1100000 0