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Goodwill and Intangible Assets - Gross Carrying Amounts and Net Book Values of Intangible Assets (Details) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 7,064,245 $ 8,210,692
Accumulated Amortization (1,493,851) (1,213,350)
Total 5,570,394 6,997,342
Intangible Assets [Line Items]    
Intangible assets, gross 7,064,245 8,365,678
Intangible assets, net 5,570,394 7,152,328
Acquired in-process research and development assets    
Intangible Assets [Line Items]    
Acquired in-process research and development assets 0 154,986
Impairment of our acquired IPR&D asset $ 133,800  
Acquired developed technologies    
Finite-Lived Intangible Assets [Line Items]    
Remaining Weighted- Average Useful Life (In years) 10 years 8 months 12 days  
Gross Carrying Amount $ 7,050,958 8,195,675
Accumulated Amortization (1,480,564) (1,198,333)
Total $ 5,570,394 6,997,342
Manufacturing contracts    
Finite-Lived Intangible Assets [Line Items]    
Remaining Weighted- Average Useful Life (In years) 0 years  
Gross Carrying Amount $ 10,435 12,124
Accumulated Amortization (10,435) (12,124)
Total $ 0 0
Trademarks    
Finite-Lived Intangible Assets [Line Items]    
Remaining Weighted- Average Useful Life (In years) 0 years  
Gross Carrying Amount $ 2,852 2,893
Accumulated Amortization (2,852) (2,893)
Total $ 0 $ 0